Blood Test Results After Organic Solvent Poisoning - Internal Medicine

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Blood tests after organic solvent poisoning?


Recently, I experienced poisoning due to organic solvents and felt unwell the next day, so I went to the hospital for an examination.
Blood and urine samples were taken, and the report showed several abnormal values highlighted in red: S-GOT 45 U/L, S-GPT 61 U/L, fasting blood glucose 116 mg/dL, neutrophils 89.6% (normal range 40-75%), and lymphocytes 7.4% (normal range 18-45%).
I would like to ask the physician what I should pay attention to and how to improve my condition.

Mr. Zeng, 30~39 year old female. Ask Date: 2021/01/22

Dr. Su Zhehong reply Internal Medicine


Excessive exposure to organic solvents may lead to liver damage, but this blood test report shows that the levels of AST and ALT have not increased more than twofold.
It is recommended to first consult a gastroenterologist for further evaluation to rule out other causes of liver function abnormalities.
If it is related to the work environment, a visit to an occupational medicine specialist for examination and consultation may also be beneficial.
Regarding blood glucose levels, it is important to check whether the fasting period before the blood draw was at least 8 hours, as the standards may vary.
It is advisable to follow up in one month; if fasting blood glucose remains above 100 mg/dL, a referral to an endocrinologist for further monitoring is recommended.

Reply Date: 2021/01/22

More Info


Based on the blood test results you provided after exposure to organic solvents, there are several key points to consider regarding your health and the implications of these results.

Firstly, the elevated levels of S-GOT (AST) and S-GPT (ALT) indicate some degree of liver stress or damage. Normal ranges for AST and ALT are typically around 10-40 U/L, so your results of 45 U/L for AST and 61 U/L for ALT suggest mild liver enzyme elevation. While these levels are not alarmingly high, they do warrant attention, especially in the context of organic solvent exposure, which is known to potentially cause liver injury. It is advisable to consult a gastroenterologist for further evaluation to rule out other causes of liver dysfunction and to monitor your liver health over time.

Regarding your blood glucose level of 116 mg/dL, this is slightly above the normal fasting range (typically less than 100 mg/dL). If this reading was taken after fasting for at least 8 hours, it may indicate a state of prediabetes or impaired glucose tolerance. It would be prudent to follow up with an endocrinologist for further assessment, especially if you have risk factors for diabetes or a family history of the disease. Regular monitoring of your blood sugar levels and lifestyle modifications, such as a balanced diet and regular exercise, can help manage and potentially improve your glucose levels.

The differential white blood cell count shows a significant increase in neutrophils (89.6%), which is above the normal range of 40-75%. This could indicate an acute inflammatory response, possibly due to the exposure to organic solvents or another underlying infection or stressor. The lymphocyte count is low at 7.4% (normal range is 18-45%), which can sometimes occur in acute stress situations or infections. It is essential to monitor these counts and discuss them with your healthcare provider, as they can provide insights into your immune response and overall health.

In terms of improving your health following organic solvent exposure, here are some recommendations:
1. Avoid Further Exposure: Ensure that you are not exposed to organic solvents in your work or home environment. Proper ventilation and personal protective equipment (PPE) are crucial when working with such substances.

2. Regular Monitoring: Schedule follow-up blood tests to monitor liver function and glucose levels. This will help track any changes and ensure that any potential issues are addressed promptly.

3. Healthy Lifestyle: Adopt a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Regular physical activity can help improve liver health and regulate blood sugar levels.

4. Hydration: Stay well-hydrated, as this can aid in the detoxification process and support liver function.

5. Consult Specialists: As mentioned earlier, seeing a gastroenterologist for liver function evaluation and an endocrinologist for blood sugar management is advisable. They can provide tailored advice and treatment options based on your specific situation.

6. Mental Health: Exposure to toxic substances can also have psychological effects. If you are experiencing anxiety or stress related to your health, consider speaking with a mental health professional.

In conclusion, while your blood test results indicate some areas of concern, they are not necessarily indicative of severe damage. However, proactive monitoring and lifestyle adjustments are essential to ensure your health remains stable and to prevent any potential complications. Always consult with your healthcare provider for personalized advice and treatment options.

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