Can Ginkgo Biloba Supplements Be Safe for Patients with Favism? - Family Medicine

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Hello Doctor, I have favism and I am considering purchasing SANDOZ's 40mg Ginkgo biloba extract coated tablets for health purposes.
I have heard that patients with favism should avoid products containing ginkgo.
Is this true? Thank you for your assistance.

Guo, 20~29 year old female. Ask Date: 2021/01/27

Dr. Cai Dongqi reply Family Medicine


Hello: There is indeed an impact; for detailed information, please consult a pediatrician or a pharmacist.

Reply Date: 2021/01/27

More Info


When considering the safety of Ginkgo Biloba supplements for patients with Favism (G6PD deficiency), it is essential to understand both the nature of the condition and the properties of Ginkgo Biloba. Favism is a genetic disorder characterized by the deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD), which plays a crucial role in protecting red blood cells from oxidative stress. Individuals with this condition can experience hemolytic anemia when exposed to certain triggers, including specific foods, medications, and environmental factors.

Ginkgo Biloba is a popular herbal supplement often used for its potential cognitive benefits, including improved memory and concentration. However, it also has properties that can affect blood circulation and may interact with certain medications, particularly anticoagulants and antiplatelet drugs. The concern for patients with G6PD deficiency arises from the potential for Ginkgo Biloba to induce oxidative stress, which could exacerbate the hemolytic episodes characteristic of Favism.

While there is no definitive evidence directly linking Ginkgo Biloba to adverse effects in G6PD-deficient individuals, caution is warranted. The literature does not provide conclusive data on the safety of Ginkgo Biloba for those with Favism, and some anecdotal reports suggest that certain herbal supplements can trigger hemolytic reactions. Therefore, it is prudent for patients with G6PD deficiency to avoid Ginkgo Biloba until more is known about its safety profile in this population.

If you are considering taking Ginkgo Biloba or any other supplement, it is crucial to consult with your healthcare provider first. They can assess your specific health situation, including your G6PD status, any other medications you may be taking, and your overall health. Your doctor may also recommend alternative supplements or therapies that are safer for individuals with G6PD deficiency.

In summary, while Ginkgo Biloba is generally considered safe for the general population, its use in patients with Favism should be approached with caution due to the potential risk of oxidative stress and hemolytic reactions. Always consult with a healthcare professional before starting any new supplement, especially if you have a known medical condition like G6PD deficiency.

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