Spironolactone for Acne Treatment in Men: Safety and Side Effects - Dermatology

Share to:

Questions about acne medications?


I am male, and I visited a dermatologist for acne issues on my chin.
However, the doctor prescribed me spironolactone and doxylamine capsules.
I heard that spironolactone, a diuretic, is usually prescribed only for females.
The doctor prescribed half a tablet to be taken once a day for a total of seven days.
Is it really safe for me to take this? Will the side effects resolve after stopping the medication?

Hsuān, 30~39 year old female. Ask Date: 2021/02/25

Dr. Wu Yuxin reply Dermatology


You should consult your attending physician about this issue, as they are most familiar with your condition and can help you choose the appropriate medication.

Reply Date: 2021/02/25

More Info


Spironolactone is a medication primarily known as a potassium-sparing diuretic, but it has also been used off-label for the treatment of acne, particularly in women. Its mechanism of action involves antagonizing the effects of androgens, which are hormones that can contribute to acne development by increasing oil production in the skin. While it is more commonly prescribed to women, particularly those with hormonal acne, it can also be prescribed to men under certain circumstances.

In your case, the dermatologist has prescribed spironolactone for your chin acne, which may indicate that they believe your acne could be influenced by hormonal factors. The dosage of half a tablet once daily for seven days is relatively low, and while spironolactone is generally considered safe, it does come with potential side effects. Common side effects include dizziness, gastrointestinal disturbances, and changes in menstrual cycles for women. In men, it can lead to breast tenderness or gynecomastia (enlargement of breast tissue), although these side effects are less common.

Regarding your concern about safety, it is essential to follow your dermatologist's guidance. They are familiar with your medical history and the specifics of your condition. If you experience any unusual symptoms or side effects, it is crucial to communicate these to your healthcare provider promptly.
As for the question of whether side effects will resolve after stopping the medication, in most cases, any side effects experienced from spironolactone should diminish after discontinuation. The body typically metabolizes and clears the medication, and any hormonal effects it may have had will also subside. However, the timeline for this can vary depending on individual factors such as metabolism and overall health.

It's also worth noting that while spironolactone can be effective for acne treatment, it may not be the first-line treatment for men. Other options, such as topical retinoids, benzoyl peroxide, or oral antibiotics like doxycycline, are often preferred. If you have concerns about the appropriateness of spironolactone for your acne, discussing these with your dermatologist could provide clarity and potentially lead to alternative treatment options.

In conclusion, while spironolactone can be used in men for acne treatment, it is essential to monitor for any side effects and maintain open communication with your healthcare provider. If you have any lingering concerns or experience adverse effects, do not hesitate to reach out to your dermatologist for further evaluation and guidance.

Similar Q&A

Understanding Androcur for Acne: Side Effects and Alternatives Explained

To treat acne, I underwent blood tests that showed elevated testosterone levels and have been taking Androcur for several months. However, my libido has significantly decreased. Previously, I would wake up with an erection every morning, but now that doesn't happen. I am cur...


Dr. Xiao Yongxun reply Internal Medicine
Dear Mr. Cong: 1. Androcur® (50mg, generic name: Cyproterone) is indicated for the treatment of prostate tumors, severe hypersexuality, significant masculinization symptoms, hirsutism, acne, and more. Potential side effects may include nausea, vomiting, abdominal pain, slight we...

[Read More] Understanding Androcur for Acne: Side Effects and Alternatives Explained


Can Spironolactone Help Men with Male Pattern Baldness?

Hello Doctor, I have "central serous chorioretinopathy" and I am currently taking Spironolactone. Unfortunately, I was recently diagnosed with male pattern baldness. Typically, treatments for male pattern baldness involve Finasteride, but I found that Spironolactone als...


Dr. Wu Yuxin reply Dermatology
It does not cause feminization and does not have the effect of treating male pattern baldness. Only finasteride has the ability to inhibit DHT, which leads to hair miniaturization.

[Read More] Can Spironolactone Help Men with Male Pattern Baldness?


Concerns About Spironolactone Use and Breast Cancer Risk

Hello Dr. Chen, I have been experiencing acne for a long time. The medication prescribed to me has "diuretic" written on the bag, and I am wondering if it refers to Spironolactone. Recently, I read in a magazine that it should not be taken if there is a family history o...


Dr. Chen Yiying reply Dermatology
The diuretic you mentioned for treating acne is likely spironolactone. In fact, there is no evidence to support that the use of spironolactone increases the risk of breast cancer; however, it is suggested that patients with a family history of breast cancer should avoid its use. ...

[Read More] Concerns About Spironolactone Use and Breast Cancer Risk


Long-Term Acne Treatment: Risks and Effects on Liver and Kidneys

Dear Dr. Jiang: I have been experiencing acne for nearly six months and started seeing a dermatologist during that time. Since then, I have been taking medication daily (one packet per day). I have been on this regimen for six months, and I am concerned about potential adverse ...


Dr. Jiang Zheen reply Dermatology
The listed medications can be safely taken under the assessment of a qualified physician. However, it is advisable to return for follow-up appointments as scheduled.

[Read More] Long-Term Acne Treatment: Risks and Effects on Liver and Kidneys


Related FAQ

Medication Side Effects

(Dermatology)

Oral Isotretinoin

(Dermatology)

Acne

(Internal Medicine)

Acne Scars

(Dermatology)

Acne

(Traditional Chinese Medicine)

Azelaic Acid

(Dermatology)

Sebaceous Glands

(Urology)

Seborrheic Dermatitis

(Dermatology)

Frequent Facial Redness

(Dermatology)

Sebum Production

(Dermatology)