Is Strocaine Safe for Kidney Health After Long-Term Use?

Regarding stomach medication, Strocaine (Oxethazaine/Polymigel) is a medication used to relieve symptoms associated with gastric irritation?

Hello Dr.
Wu: Two weeks ago, I experienced some mild abdominal pain.
It usually doesn't happen during the day, but occurs around six or seven in the evening before dinner.
After eating, the pain significantly improves.
My mother had some gastrointestinal issues and visited the hospital a few times, so she had some leftover medication.
She mentioned that Acetaminophen (Tylenol) is very effective.
Initially, I still felt pain when I started taking it, but I took one tablet after each meal for nine consecutive days, and I haven't had any episodes for the past five days.
I would like to ask the doctor if taking Acetaminophen for nine days could have any impact or damage to my kidneys.
Thank you for your guidance.

Azheng, 30~39 year old female. Ask Date: 2021/04/19

Dr. Wu Jiyu reply Internal Medicine

Strocaine is a local anesthetic combined with an antacid.
According to the approved indications in the package insert, it is used for stomach pain and heartburn caused by excessive gastric acid.
It generally has no impact on the kidneys.
If stomach pain recurs, it is recommended to arrange for an endoscopy or abdominal ultrasound to clarify the condition.
Thank you for your inquiry.
The Nephrology Department of Changhua Hospital is concerned about your health.

Reply Date: 2021/04/19

More Info

Strocaine, which is a brand name for a combination medication that typically includes acetaminophen (paracetamol) and other ingredients, can indeed raise concerns regarding kidney health, especially with long-term use. Acetaminophen is generally considered safe for most people when taken at recommended doses; however, excessive or prolonged use can lead to potential risks, particularly for individuals with pre-existing kidney conditions.

Understanding the Risks
1. Kidney Function and Acetaminophen: Acetaminophen is metabolized primarily in the liver, but its metabolites can affect kidney function if taken in high doses or over extended periods. Chronic use can lead to nephrotoxicity, especially in individuals with compromised kidney function or those who consume alcohol regularly.

2. Dosage Considerations: The recommended maximum daily dose for acetaminophen is typically 4,000 mg for adults, but lower limits are advised for those with liver or kidney issues. If you have been taking Strocaine (or any acetaminophen-containing medication) consistently for nine days, it is essential to ensure that your total daily intake does not exceed safe limits.

3. Signs of Kidney Damage: Symptoms of potential kidney damage can include decreased urine output, swelling in the legs or ankles, fatigue, and confusion. If you experience any of these symptoms, it is crucial to seek medical attention promptly.

4. Consulting Healthcare Professionals: Given your concerns about kidney health, it is advisable to consult with a healthcare professional who can evaluate your kidney function through blood tests (such as serum creatinine and blood urea nitrogen) and provide personalized advice based on your health history.

Recommendations for Safe Use
- Limit Duration and Dosage: If you need to use Strocaine or any acetaminophen-containing medication, limit its use to the shortest duration necessary and adhere strictly to the recommended dosage.

- Monitor Symptoms: Keep track of any symptoms that may arise during or after the use of the medication. If you notice any adverse effects, discontinue use and consult a healthcare provider.

- Hydration: Staying well-hydrated can help support kidney function, especially when taking medications that may stress the kidneys.

- Regular Check-Ups: If you have a history of kidney issues or are concerned about your kidney health, regular check-ups with your healthcare provider are essential. They can monitor your kidney function and adjust any medications as needed.

Conclusion
In summary, while Strocaine can be effective for managing pain, its long-term use, particularly in individuals with kidney concerns, should be approached with caution. Always consult with a healthcare professional before starting or continuing any medication, especially if you have underlying health conditions. They can provide guidance tailored to your specific health needs and help ensure that your kidney health remains a priority.

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