The issue of egg freezing?
Hello Dr.
Tsao: I read an article stating that breast cancer patients undergoing assisted reproduction should control the dosage of ovulation induction medications and keep estrogen levels relatively low to prevent recurrence of breast cancer.
My mother and aunt have had breast cancer, and there is a breast cancer gene in my family.
I underwent a normal egg freezing procedure without controlling for lower estrogen levels.
Am I at risk of inducing breast cancer? I am very concerned.
Thank you for your response.
c, 30~39 year old female. Ask Date: 2021/04/22
Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, it generally does not have a significant impact.
Wishing you good health.
Reply Date: 2021/04/22
More Info
When considering the relationship between egg freezing and breast cancer risk, particularly for women with a family history of breast cancer or known genetic predispositions, it's essential to understand the underlying factors involved in both fertility treatments and cancer risk.
Firstly, it is important to note that the use of hormonal medications during egg freezing procedures, such as gonadotropins, is a standard practice. These medications stimulate the ovaries to produce multiple eggs, which can then be retrieved for freezing. Concerns have been raised about the potential impact of these hormones on breast cancer risk, especially in women with a family history of the disease. However, current research indicates that the use of fertility medications does not significantly increase the risk of developing breast cancer. Studies have shown that women who undergo ovarian stimulation for in vitro fertilization (IVF) do not have a higher incidence of breast cancer compared to the general population.
In your case, since you have a family history of breast cancer, it is understandable to be concerned about the implications of hormone therapy. The key factor to consider is the type and dosage of hormones used during the egg freezing process. While some articles suggest that lower doses of estrogen may be advisable for women at high risk for breast cancer, the consensus among medical professionals is that the benefits of egg freezing, particularly for women who wish to preserve their fertility, generally outweigh the potential risks associated with hormonal stimulation.
Moreover, the relationship between estrogen and breast cancer is complex. Estrogen can promote the growth of certain types of breast cancer cells, but the levels of estrogen used in fertility treatments are typically not sufficient to trigger cancer development in women who are otherwise healthy. For those with a known genetic predisposition, such as BRCA mutations, discussions with a healthcare provider specializing in reproductive endocrinology and oncology can help tailor a treatment plan that minimizes risks while maximizing the chances of successful egg retrieval.
In addition to hormonal considerations, regular monitoring and screening for breast cancer are crucial for women with a family history of the disease. This includes routine mammograms and clinical breast exams, as well as discussions about genetic testing if you have not already pursued this avenue. Understanding your specific risk factors can help guide decisions about fertility treatments and overall health management.
If you have already undergone the egg freezing process without the use of lower estrogen levels, it is essential to remember that the procedure is generally considered safe, and the likelihood of inducing breast cancer is low. However, maintaining open communication with your healthcare providers about your concerns and any symptoms you may experience is vital. They can provide personalized advice and reassurance based on your medical history and family background.
In conclusion, while it is natural to have concerns about the implications of egg freezing on breast cancer risk, current evidence suggests that the procedure is safe for women, even those with a family history of breast cancer. Regular screenings and consultations with healthcare professionals can further ensure that you are taking the necessary steps to protect your health while pursuing your reproductive goals.
Similar Q&A
Concerns About Egg Freezing and Breast Cancer Risk in Women
Hello Dr. Tsao: I read an article stating that breast cancer patients undergoing assisted reproductive technology should control the dosage of ovulation induction medications and keep estrogen levels relatively low to prevent recurrence of breast cancer. My mother and aunt have h...
Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, it's generally not a concern, so don't worry. Wishing you good health.[Read More] Concerns About Egg Freezing and Breast Cancer Risk in Women
Does Birth Control Affect Egg Quality for Oocyte Freezing?
Hello, doctor. I previously visited the obstetrics and gynecology department for menstrual regulation due to a business trip, and the doctor prescribed Norlina 5 mg, which I took from April 24 to April 29. I am considering egg freezing and plan to undergo the procedure in mid-Aug...
Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, it generally does not have an impact. Wishing you good health.[Read More] Does Birth Control Affect Egg Quality for Oocyte Freezing?
Freezing Eggs: Do Antipsychotic Medications Affect the Process?
Do individuals with schizophrenia need to stop egg freezing?
Dr. Liang Sunyuan reply Psychiatry
Hello Ms. Yang: Generally speaking, antipsychotic medications do not affect egg health, and it is usually not necessary to discontinue them. It is recommended to confirm this with a gynecologist.[Read More] Freezing Eggs: Do Antipsychotic Medications Affect the Process?
Does Radiation Exposure Affect Egg Quality for IVF?
I underwent abdominal, chest, and lumbar X-rays once each in August this year during a health check-up. From September to December, I had full mouth X-rays three times and single tooth X-rays four times at the dental clinic. Due to suspected myocardial ischemia, I underwent a car...
Dr. Wang Yifen reply Radiology
Hello, in most cases, the reasons affecting ovarian reserve are unclear, with aging being the primary factor related to reproductive age. Other factors that may influence ovarian reserve include smoking, lifestyle habits, medical history, previous ovarian surgeries, systemic chem...[Read More] Does Radiation Exposure Affect Egg Quality for IVF?
Related FAQ
(Obstetrics and Gynecology)
Breast Cancer(Obstetrics and Gynecology)
Menopause(Obstetrics and Gynecology)
Ovulation(Obstetrics and Gynecology)
Hormonal Imbalance(Obstetrics and Gynecology)
Pcos(Obstetrics and Gynecology)
Menstrual Abnormalities(Obstetrics and Gynecology)
Pms(Obstetrics and Gynecology)
Menstrual Regulation(Obstetrics and Gynecology)
Human Papillomavirus(Obstetrics and Gynecology)