Exploring the Connection Between Viagra Use and Chronic Fatigue - Urology

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The relationship between Viagra and frequent fatigue or sleepiness?


My boyfriend says that being single was less exhausting, but being in a relationship is tiring and he often needs to catch up on sleep.
Doctors have been unable to find a cause and even suggested he see a psychologist.
He is currently in Australia and is unsure about the quality of healthcare here.
Today, he wondered if it could be related to Viagra (sildenafil).
Are there alternative medications? Or how can he stop using Viagra? Thank you.

Lurén, 30~39 year old female. Ask Date: 2021/05/03

Dr. Du Shixi reply Urology


Hello: You may refer to the document titled "Post-Marketing Data of Pharmaceuticals," which can be found at the provided link.
It states that there should be no such symptoms.
Wishing you good health.

Reply Date: 2021/05/03

More Info


The connection between the use of Viagra (sildenafil) and chronic fatigue is an interesting topic that warrants careful consideration. Sildenafil is primarily known as a phosphodiesterase type 5 (PDE5) inhibitor, which is used to treat erectile dysfunction (ED) by increasing blood flow to the penis. While it is effective for its intended purpose, there are several factors to consider regarding its potential impact on energy levels and fatigue.

Firstly, it is essential to understand that sildenafil itself is not directly linked to causing chronic fatigue. However, the context in which it is used may contribute to feelings of tiredness. For instance, if your boyfriend is experiencing relationship-related stress or anxiety, this could lead to fatigue. Stress can significantly impact energy levels, and the pressure to perform sexually can exacerbate this. If he feels more relaxed and confident in a relationship, it could lead to a different psychological state compared to being single, which might explain his feelings of fatigue.

Moreover, sildenafil can have side effects that may indirectly contribute to feelings of tiredness. Common side effects include headaches, flushing, and gastrointestinal discomfort. While these side effects are generally mild, they can be bothersome enough to affect overall well-being and energy levels. If your boyfriend is experiencing these side effects, it might be worth discussing with a healthcare provider to see if an alternative medication could be more suitable.

In terms of alternatives to sildenafil, there are several options available. Other PDE5 inhibitors, such as tadalafil (Cialis) and vardenafil (Levitra), may have different side effect profiles and durations of action. Tadalafil, for instance, has a longer half-life, allowing for more spontaneity in sexual activity, which might reduce performance anxiety and associated fatigue.

Additionally, non-pharmacological approaches can be beneficial. Lifestyle changes, such as regular exercise, a balanced diet, and adequate sleep, can improve energy levels and overall health. Psychological support, such as counseling or therapy, can also help address any underlying anxiety or stress that may be contributing to feelings of fatigue.

If your boyfriend is considering discontinuing sildenafil, it is crucial to do so under the guidance of a healthcare professional. They can help assess his specific situation, explore the reasons for his fatigue, and suggest appropriate alternatives or lifestyle modifications. It is also essential to rule out any underlying medical conditions that could be contributing to his fatigue, such as sleep apnea, thyroid issues, or other hormonal imbalances.

In conclusion, while sildenafil itself is not directly linked to chronic fatigue, the context of its use and the psychological factors surrounding relationships can play a significant role in how one feels. Exploring alternatives and addressing lifestyle factors can be beneficial in managing fatigue. It is always advisable to consult with a healthcare provider to tailor a treatment plan that best suits individual needs and circumstances.

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