Anxiety and Panic Disorders: Concerns About Abilify Use - Psychiatry

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Medication Issue - I was prescribed Abilify by my doctor for panic and anxiety disorders, but it has made my anxiety worse?


Hello, Doctor.
I have a severe panic disorder and health anxiety, which seems to be hereditary as some of my cousins have obsessive-compulsive disorder and depression.
During severe episodes, I experience feelings of derealization and unreality.
After acute panic attacks, I often suffer from health anxiety for several months.
I have been seeing a psychiatrist at a major hospital and have been taking Zoloft (sertraline) for ten years.
There were long periods of stability, but recently I have experienced another wave of panic and anxiety.
I find myself constantly searching online for information, unable to stop, and I am very afraid that I might have a serious mental illness beyond just panic disorder.
I often look up symptoms and causes related to derealization, which only increases my fear and makes me question whether I truly have a severe mental illness.
When I returned for a follow-up with my psychiatrist, after listening to my concerns, the doctor prescribed Abilify (aripiprazole) in addition to Zoloft.
Upon researching it online, I discovered that it is an antipsychotic medication, which heightened my panic and anxiety.
I keep asking my parents if I have exhibited any unusual behaviors throughout my life, and they say that aside from my constant worry about being ill and dying, they have not noticed anything particularly concerning.
My father mentioned that our family has a significant tendency toward anxiety.
However, the prescription of Abilify has been troubling me.
I am very worried that I might actually have schizophrenia or bipolar disorder.
When I asked the doctor about it, he simply told me, "You shouldn't research on your own; you should trust your doctor.
Many drug mechanisms are beyond your understanding," which only increased my anxiety.
I know I should trust my doctor, but I cannot stop my anxiety, and it seems the doctor is unwilling to spend more time explaining things to me, just prescribing medication and telling me to take it.
This vague and unknown situation makes me very uneasy.

Is it common for general neuroses to require antipsychotic medications like this? Does being prescribed such medication imply that I truly have a certain degree of schizophrenia that necessitates treatment with this type of drug? Currently, I am still only taking my original dose of Zoloft, two pills daily, and I am really afraid to take Abilify.
I feel helpless, and even my primary physician is not willing to explain much to me.
I hope to receive some answers.
Thank you very much!

A-Heng, 20~29 year old female. Ask Date: 2021/05/24

Dr. Lin Mianzhang reply Psychiatry


Hello Ah-Heng: I can sense that your anxiety level is quite high, and I empathize with you! Abilify can be used to treat schizophrenia (previously referred to as psychosis), bipolar disorder, and other major mental illnesses.
Additionally, it can serve as an adjunct treatment for depression.
However, it is generally not prescribed until the dosage of antidepressants has reached the maximum level.
You mentioned that you are only taking two pills of Zoloft, which has not yet reached the maximum dosage, so I don’t quite understand the rationale behind your doctor’s prescription.
You may need to consult your primary physician about this! Of course, if you are concerned, it is also acceptable to refrain from taking this medication, but you should consider the reasons behind the recent worsening of your panic and anxiety symptoms.
Have there been any recent events or stressors? Identifying the cause can help you understand how to improve your anxiety symptoms.
Additionally, practicing diaphragmatic breathing can help stabilize your mood and autonomic nervous system, which may also alleviate anxiety and panic symptoms.
Wishing you a speedy recovery.

Reply Date: 2021/05/24

More Info


It's understandable to feel anxious and confused about the use of medications like Abilify, especially when you have a history of anxiety and panic disorders. Your concerns are valid, and it's important to address them with accurate information.

First, it's essential to clarify that Abilify (aripiprazole) is an atypical antipsychotic medication that is often used to treat conditions such as schizophrenia, bipolar disorder, and as an adjunct treatment for major depressive disorder. However, it is also used in some cases to help manage anxiety and panic disorders, particularly when other treatments have not been effective. The decision to prescribe Abilify alongside Zoloft (sertraline) may be based on your doctor's assessment of your symptoms and their severity.

Your experience of feeling detached from reality and experiencing panic attacks can be distressing. These symptoms are often associated with anxiety disorders, including panic disorder and generalized anxiety disorder. It's common for individuals with anxiety disorders to worry excessively about their mental health, leading to a cycle of fear and anxiety about potential diagnoses. This is sometimes referred to as "health anxiety" or "hypochondria."
Regarding your concern about whether taking Abilify indicates that you have a severe mental illness like schizophrenia, it's crucial to understand that the use of this medication does not automatically mean you have such a condition. Many doctors prescribe antipsychotic medications for a variety of reasons, including to stabilize mood and reduce anxiety symptoms. Your doctor likely believes that Abilify could help manage your anxiety and panic symptoms more effectively than Zoloft alone.

It's also important to note that the stigma surrounding psychiatric medications can contribute to feelings of fear and confusion. Many people worry about the implications of taking certain medications, especially those associated with more severe mental illnesses. However, mental health treatment is highly individualized, and what works for one person may not work for another. Your treatment plan should be tailored to your specific needs and symptoms.

If you're feeling uncomfortable with the idea of taking Abilify, it's essential to communicate this with your doctor. You have the right to ask questions and seek clarification about your treatment plan. A good psychiatrist should be willing to explain the rationale behind their recommendations and address any concerns you may have. If you feel that your current doctor is not providing the support you need, it may be worth seeking a second opinion from another mental health professional.

In the meantime, consider exploring additional coping strategies to manage your anxiety. Cognitive-behavioral therapy (CBT) is an effective treatment for anxiety disorders and can help you develop skills to challenge negative thoughts and reduce anxiety. Mindfulness practices, such as meditation and deep breathing exercises, can also be beneficial in managing anxiety symptoms.

Lastly, remember that you are not alone in this journey. Many individuals experience similar feelings of anxiety and uncertainty regarding their mental health treatment. Seeking support from friends, family, or support groups can also provide comfort and understanding as you navigate your treatment options.

In summary, while Abilify is typically associated with more severe mental health conditions, its use in treating anxiety and panic disorders is not uncommon. It's essential to have open communication with your healthcare provider about your concerns and to explore additional therapeutic options that may complement your medication. Your mental health is a priority, and finding the right treatment plan is a collaborative process between you and your healthcare team.

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