Managing Dry Mouth Symptoms While Taking Tofisopam: What to Do? - Neurology

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Experiencing severe dry mouth while taking Tofacitinib (20mg)?


Hello Doctor: I have been taking Tofacitinib for almost three months and was supposed to return for a follow-up appointment! However, due to the outbreak of the pandemic, I am hesitant to go to the hospital! Recently, my dry mouth symptoms have been getting worse, even affecting my sleep! May I ask: 1.
How should I manage my dry mouth symptoms? 2.
Should I continue taking Tofacitinib? Thank you!

Gao Xiaojie, 50~59 year old female. Ask Date: 2021/06/07

Dr. Jiang Junyi reply Neurology


Dear Ms.
Gao,
Atorvastatin is indicated for: reducing the risk of myocardial infarction, lowering the risk of stroke, and decreasing the incidence of cardiovascular events in high-risk groups for coronary heart disease.
Since you are 50 years old, I would like to know which risk factors you aim to lower.
It is recommended to start with a half dose, which still provides about 70% efficacy, and then check your blood levels to see if you reach the target.
Common side effects of atorvastatin include headache, diarrhea, vomiting, bloating, and constipation; these symptoms typically diminish over time.
More serious side effects may include unusual muscle pain, cramps, or an unusual feeling of weakness, jaundice around the eyes or skin, lower back pain, and skin allergies.
The dry mouth you mentioned may require consideration of other medications or the influence of female hormones.
Additionally, sleep apnea can also cause dry mouth.
I suggest starting with vitamin supplementation and hydration, sleeping on your left side, ensuring adequate rest, and enhancing your body's self-healing ability.
If symptoms progress, it is advisable to follow up with your primary care physician for further evaluation.
Thank you for your inquiry, and feel free to discuss any related questions!
Wishing you good health and peace,
Dr.
Jiang Junyi, Taoyuan Medical Center

Reply Date: 2021/06/07

More Info


Managing dry mouth, especially when it is a side effect of medication like Tofisopam (also known as 妥寧), can be quite challenging. Dry mouth, or xerostomia, can lead to discomfort, difficulty swallowing, and even dental issues if not addressed properly. Here are some strategies to manage your symptoms effectively:
1. Stay Hydrated: One of the simplest ways to alleviate dry mouth is to increase your fluid intake. Drink plenty of water throughout the day. Consider keeping a water bottle with you to remind yourself to sip regularly. Additionally, drinking water before bed can help reduce nighttime dryness.

2. Use Saliva Substitutes: Over-the-counter saliva substitutes can provide temporary relief. These products are designed to mimic natural saliva and can help keep your mouth moist. Look for products that are sugar-free to avoid any potential dental issues.

3. Chew Sugar-Free Gum or Suck on Sugar-Free Candies: Chewing gum or sucking on candies can stimulate saliva production. Opt for sugar-free varieties to protect your teeth. Look for gum or candies that contain xylitol, which can also help reduce the risk of cavities.

4. Avoid Certain Foods and Beverages: Some foods and drinks can exacerbate dry mouth symptoms. Avoid caffeine, alcohol, and spicy or acidic foods, as they can irritate the mouth and worsen dryness. Instead, focus on soft, moist foods that are easier to swallow.

5. Use a Humidifier: If dry mouth is affecting your sleep, consider using a humidifier in your bedroom. This can add moisture to the air and help alleviate dryness during the night.

6. Practice Good Oral Hygiene: Maintaining good oral hygiene is crucial, especially when experiencing dry mouth. Brush your teeth at least twice a day and floss daily. Consider using a fluoride toothpaste and mouthwash designed for dry mouth. Regular dental check-ups are also important to monitor any potential issues.

7. Consult Your Doctor: Since you mentioned that you have been taking Tofisopam for nearly three months and are experiencing worsening dry mouth symptoms, it is essential to discuss this with your healthcare provider. They can evaluate whether the benefits of continuing the medication outweigh the side effects. In some cases, your doctor may suggest adjusting the dosage or switching to a different medication that has a lower risk of causing dry mouth.

8. Consider Other Treatments: If your dry mouth persists despite these measures, your doctor may prescribe medications that stimulate saliva production, such as pilocarpine or cevimeline. These medications can help improve saliva flow and alleviate symptoms.

In summary, managing dry mouth while taking Tofisopam involves a combination of lifestyle changes, over-the-counter products, and possibly adjustments to your medication regimen. It’s crucial to communicate openly with your healthcare provider about your symptoms and concerns, especially since they are affecting your sleep and overall quality of life. They can provide personalized recommendations and ensure that you receive the best care possible.

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