Zinc Deficiency: Symptoms, Treatment, and Safety Concerns - Family Medicine

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Hello, doctor.
I would like to ask two questions.
First, is there any toxicity associated with heating glucosamine zinc tablets? I usually dissolve them in hot water before taking them.
Second, I have an anal fissure, chronic acne on my skin, oily and itchy skin around my eyes, and I have been experiencing chronic glossitis, specifically with fungiform papillae and geographic tongue.
These issues, including the anal fissure, appeared simultaneously, with glossitis being the most bothersome.
I have even noticed some areas of atrophy.
I have tried taking B vitamins, but they were ineffective.
Later, I personally tried taking zinc tablets, and all the aforementioned symptoms improved.
After taking zinc tablets for a week, I still experience some warmth, but the atrophic areas have significantly regrown.
Could this indicate a zinc deficiency?

Niming, 30~39 year old female. Ask Date: 2021/07/10

Dr. Wu Zongying reply Family Medicine


Hello: Soaking in regular warm water may damage zinc.
Zinc is found in many types of food, such as seafood (especially oysters), whole grains, cereals, nuts, meats (red meat and poultry), legumes, and dairy products.
If you typically do not lack these foods in your diet, you should not experience these symptoms due to zinc deficiency.
Your symptoms may require adjustments in your lifestyle and dietary habits for improvement.
It is recommended to reduce the intake of fried foods, butter cakes, sweets, and sugary beverages; increase the consumption of vegetables and fruits; exercise more; and maintain an early bedtime, among other suggestions.

Reply Date: 2021/07/10

More Info


Zinc deficiency is a significant health concern that can lead to a variety of symptoms and complications. Zinc is an essential trace mineral that plays a crucial role in numerous biological functions, including immune response, protein synthesis, wound healing, DNA synthesis, and cell division. Understanding the symptoms, treatment options, and safety concerns related to zinc deficiency is vital for maintaining overall health.


Symptoms of Zinc Deficiency
Zinc deficiency can manifest in several ways, including:
1. Immune Dysfunction: Increased susceptibility to infections due to impaired immune function.

2. Skin Issues: Conditions such as acne, eczema, and dermatitis can worsen with zinc deficiency. Symptoms may include rashes, lesions, and delayed wound healing.

3. Gastrointestinal Problems: Diarrhea and gastrointestinal disturbances can occur.

4. Neurological Symptoms: Changes in taste and smell, as well as cognitive impairments, can be linked to low zinc levels.

5. Oral Health Issues: Chronic conditions like glossitis (inflammation of the tongue) and angular cheilitis (cracks at the corners of the mouth) may arise.

6. Hair Loss: Thinning hair or alopecia can be a sign of inadequate zinc levels.

In your case, the presence of chronic tongue inflammation (glossitis), skin issues, and the improvement of symptoms after taking zinc supplements suggest that you may indeed be experiencing zinc deficiency.


Treatment for Zinc Deficiency
The treatment for zinc deficiency typically involves dietary changes and supplementation. Foods rich in zinc include:
- Meat (especially red meat)
- Shellfish (like oysters, which are particularly high in zinc)
- Legumes (beans, lentils)
- Seeds and nuts
- Dairy products
- Whole grains
If dietary changes are insufficient, zinc supplements can be beneficial. However, it is essential to consult with a healthcare provider before starting any supplementation, as excessive zinc intake can lead to toxicity and adverse effects.


Safety Concerns Regarding Zinc Supplementation
1. Toxicity: While zinc is essential, excessive intake can lead to toxicity. Symptoms of zinc toxicity include nausea, vomiting, loss of appetite, stomach cramps, diarrhea, and headaches. Chronic high doses can interfere with the absorption of other essential minerals, such as copper.


2. Heat and Zinc Supplements: Regarding your question about heating glucosamine zinc tablets, it is generally not recommended to heat supplements unless specified by the manufacturer. High temperatures can potentially alter the chemical composition of the supplement, leading to reduced efficacy or the formation of harmful compounds. It's best to take supplements as directed, typically with water at room temperature.

3. Interactions with Other Medications: Zinc can interact with certain medications, including antibiotics and diuretics. Always inform your healthcare provider about any supplements you are taking to avoid potential interactions.


Conclusion
Based on your symptoms and the improvement you have experienced with zinc supplementation, it is plausible that you were experiencing zinc deficiency. However, it is crucial to have a healthcare professional evaluate your condition and confirm the diagnosis through appropriate testing. They can also guide you on the correct dosage of zinc supplements and monitor for any potential side effects or interactions with other medications you may be taking.

In summary, zinc plays a vital role in maintaining health, and its deficiency can lead to various symptoms. Proper treatment and monitoring are essential to ensure safety and effectiveness in addressing zinc deficiency.

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