Can You Contract Syphilis Even with Negative HIV Tests? - Urology

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HIV negative, syphilis?


If both self-testing and anonymous testing at a hospital for HIV are negative, is it still possible to contract syphilis?

Danxin, 10~19 year old female. Ask Date: 2021/08/26

Dr. Du Shixi reply Urology


Hello: An HIV test checks for HIV infection, while to determine if there is a syphilis infection, a syphilis test should be performed.
Wishing you good health.

Reply Date: 2021/08/26

More Info


Yes, it is possible to contract syphilis even if your HIV tests are negative. HIV (Human Immunodeficiency Virus) and syphilis are two distinct sexually transmitted infections (STIs) caused by different pathogens. HIV is a virus that attacks the immune system, while syphilis is caused by the bacterium Treponema pallidum.
Having a negative HIV test does not provide immunity against syphilis or any other STIs. The transmission of syphilis occurs through direct contact with syphilis sores, which can be found on the genitals, anus, or mouth during sexual activity. This means that if you engage in sexual activities with an infected partner, you can contract syphilis regardless of your HIV status.

It's important to understand that STIs can coexist. For instance, individuals who are infected with one STI, such as syphilis, may also be at higher risk for contracting HIV due to the presence of sores or inflammation that can facilitate the entry of the virus into the bloodstream. Conversely, having a negative HIV test does not mean that you are free from other STIs, including syphilis.

Regular screening for STIs is crucial, especially if you have multiple sexual partners or engage in unprotected sex. Many healthcare providers recommend routine testing for STIs, including syphilis, even if you are asymptomatic. This is because many STIs can be asymptomatic in their early stages, meaning you may not show any symptoms but could still be infected and capable of transmitting the infection to others.

If you are concerned about your risk for syphilis or any other STIs, it is advisable to consult with a healthcare professional. They can provide guidance on appropriate testing and preventive measures, such as the use of condoms, which can significantly reduce the risk of transmission of STIs, including syphilis and HIV.

In summary, while a negative HIV test is a positive outcome, it does not eliminate the risk of contracting syphilis or other STIs. Regular testing and safe sexual practices are essential components of maintaining sexual health. If you have any symptoms or concerns, do not hesitate to seek medical advice and get tested.

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