Can individuals with cholinergic urticaria receive the AZ COVID-19 vaccine?
Hello Dr.
Li, my child had Henoch-Schönlein purpura in the first grade of elementary school and has not had a recurrence since then, now at 20 years old.
However, after the second year of middle school, they developed cholinergic urticaria, which has not improved since.
They have been taking antihistamines continuously.
Is it suitable for my child to receive the AZ COVID-19 vaccine?
Xiao Ru, 40~49 year old female. Ask Date: 2021/09/15
Dr. Li Yufen reply Dermatology
Hello: Current research indicates that allergic reactions to COVID-19 vaccines are primarily due to hypersensitivity to specific adjuvants in the vaccine, which is different from the causes of cholinergic urticaria.
After vaccination, individuals should be monitored for 15 to 30 minutes, just like the general public, for any adverse reactions or allergic symptoms.
Antihistamines can still be taken before and after vaccination.
Thank you!
Reply Date: 2021/09/15
More Info
When considering whether children with cholinergic urticaria can safely receive the AZ COVID vaccine, it is essential to understand both the condition itself and the vaccine's safety profile. Cholinergic urticaria is a type of hives triggered by an increase in body temperature, often due to exercise, hot showers, or emotional stress. It is characterized by itchy welts that can appear on the skin, typically in response to these triggers.
In general, the AZ (AstraZeneca) COVID vaccine has been shown to be safe and effective for the majority of the population, including individuals with various underlying conditions. However, specific considerations must be taken into account for children with cholinergic urticaria.
1. Safety of Vaccination: The AZ vaccine has been administered to millions of people worldwide, and while some individuals may experience allergic reactions, these are typically rare. The most common side effects include mild to moderate symptoms such as pain at the injection site, fatigue, headache, and mild fever. For children with cholinergic urticaria, it is crucial to monitor for any allergic reactions post-vaccination, especially if they have a history of severe allergic responses.
2. Antihistamine Use: Since your child has been taking antihistamines to manage cholinergic urticaria, it is advisable to continue this medication as directed by your healthcare provider. Antihistamines can help mitigate any potential allergic reactions that may arise from the vaccine. It is also worth discussing with the healthcare provider whether the timing of the antihistamine dosage should be adjusted around the time of vaccination.
3. Consultation with Healthcare Providers: Before proceeding with the vaccination, it is essential to consult with your child's healthcare provider or an allergist. They can provide personalized advice based on your child's medical history, current health status, and the severity of their cholinergic urticaria. They may also recommend monitoring your child for a specific period after vaccination to ensure there are no adverse reactions.
4. Timing and Environment: Given that cholinergic urticaria can be triggered by heat and stress, it is advisable to schedule the vaccination at a time when your child is feeling well and in a calm environment. Avoiding strenuous activities before and after the vaccination can help minimize the risk of triggering urticaria.
5. General Recommendations: The Centers for Disease Control and Prevention (CDC) and other health organizations recommend that individuals with chronic conditions, including those with allergic conditions, receive the COVID vaccine unless there are specific contraindications. The benefits of vaccination, particularly in the context of the ongoing COVID-19 pandemic, generally outweigh the risks for most individuals.
In conclusion, children with cholinergic urticaria can typically receive the AZ COVID vaccine, but it is crucial to consult with a healthcare provider for tailored advice. Monitoring for any adverse reactions post-vaccination and managing the condition with antihistamines can help ensure a safe vaccination experience. Vaccination is an important step in protecting your child from COVID-19, and with proper precautions, it can be done safely.
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