Adverse Reactions to the AZ Vaccine: Chest Pain and Symptoms - Family Medicine

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Adverse reactions to the AZ vaccine?


I received the AZ vaccine on the evening of September 9th, and it has been almost a week since then.
I occasionally experience a dull pain in the upper part of my right breast, and my body temperature has been fluctuating between 36.5 and 37.5 degrees Celsius, indicating a mild fever.
Visually, the right breast appears to be swollen compared to the left breast.
Could this be a vaccine adverse reaction?

Xiao Yuan, 30~39 year old female. Ask Date: 2021/09/15

Dr. Ye Qianyu reply Family Medicine


Hello! If you experience a fever lasting more than 48 hours after receiving the vaccine, or if you develop any concerning symptoms, it is recommended that you seek medical attention at a healthcare facility.

Reply Date: 2021/09/15

More Info


After receiving the AZ vaccine, it's not uncommon for individuals to experience a range of side effects, including localized pain or discomfort in the chest area. In your case, the symptoms you describe—occasional dull pain in the upper right chest and slight swelling compared to the left breast—could potentially be related to the vaccine, but it's essential to consider other factors as well.

The AZ vaccine, like other vaccines, can trigger an immune response in the body. This response can lead to inflammation, which may manifest as pain or discomfort in various areas, including the chest. However, localized swelling and persistent pain should be evaluated further, especially if they are not resolving over time. It's important to differentiate between vaccine-related side effects and other possible conditions that could cause similar symptoms, such as musculoskeletal issues, costochondritis (inflammation of the cartilage connecting the ribs to the sternum), or even more serious conditions like myocarditis or pericarditis, which have been reported in rare cases following mRNA vaccines but are less commonly associated with the AZ vaccine.

Regarding your persistent low-grade fever (ranging from 36.5 to 37.5 degrees Celsius), this could also be a part of the body's immune response to the vaccine. Mild fever is a common side effect following vaccination, indicating that your immune system is actively responding. However, if the fever persists or worsens, it would be prudent to consult a healthcare professional.

In terms of the swelling you mentioned, it’s essential to monitor the area closely. If the swelling increases, becomes painful, or is accompanied by other symptoms such as redness, warmth, or discharge, you should seek medical attention promptly. Additionally, if you experience any symptoms such as shortness of breath, chest tightness, or palpitations, these could indicate a more serious condition that requires immediate evaluation.

As for the timing of your symptoms, it's worth noting that vaccine-related side effects typically occur within a few days to a week after vaccination. Since you received the vaccine on September 9 and are experiencing symptoms now, it is within the expected timeframe for potential side effects. However, the persistence of your symptoms beyond a week warrants further investigation.

In conclusion, while your symptoms may be related to the AZ vaccine, it is crucial to rule out other potential causes. I recommend scheduling an appointment with your healthcare provider to discuss your symptoms in detail. They may perform a physical examination and, if necessary, order imaging studies or blood tests to ensure that there are no underlying issues that need to be addressed. Remember, it’s always better to err on the side of caution when it comes to your health.

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