How Long Until I Can Sleep Normally Again After Medication? - Psychiatry

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How much longer will it take to return to normal?


Hello Doctor, I would like to inquire about medication issues.
I have been experiencing stomach pain due to autonomic nervous system dysfunction and was prescribed Lorazepam (0.5 mg) at bedtime for over three months.
Previously, I never had insomnia, only stomach pain.
After hearing from a pharmacist friend that this medication can be addictive, I decided to taper off the medication myself over three weeks and have now been off it for almost three months.
I am still having trouble sleeping; I fall asleep quickly but wake up after 2-3 hours.
I am unsure how long this will continue and whether I will experience this for the rest of my life.
Is there a possibility that my brain has been damaged and won't recover? Currently, I am seeing another doctor who prescribed half a tablet of Mirtazapine and one tablet of Tianeptine, but I still wake up after 2-3 hours.
I hope a kind doctor can see my issue and respond to help me.

Xiao Cheng, 30~39 year old female. Ask Date: 2021/11/09

Dr. Xue Gengming reply Psychiatry


It is recommended that you discuss the above situation further with your attending physician to determine if any additional examinations are necessary.
Thank you, and wishing you good health!

Reply Date: 2021/11/09

More Info


It sounds like you are experiencing significant challenges with sleep after discontinuing Lorazepam (commonly known as Ativan), which you took for over three months. It's understandable to feel anxious about the duration and severity of your insomnia, especially after having relied on medication for sleep.
When it comes to the duration of insomnia following the cessation of benzodiazepines like Lorazepam, experiences can vary widely among individuals. Generally, withdrawal symptoms, including insomnia, can last anywhere from a few days to several weeks. However, some individuals report persistent sleep disturbances that can last for months or even longer. This phenomenon is sometimes referred to as "protracted withdrawal syndrome," where symptoms can linger long after the drug has been stopped.

In your case, since you stopped taking Lorazepam three months ago and are still experiencing difficulties, it’s possible that your body is still adjusting to the absence of the medication. Benzodiazepines can alter sleep architecture, and once they are discontinued, it may take time for your brain to recalibrate its natural sleep-wake cycle. The fact that you were able to fall asleep quickly but woke up after a few hours suggests that your sleep may be fragmented, which is a common issue after stopping benzodiazepines.

It’s also important to consider that other factors may be contributing to your insomnia. For instance, anxiety, stress, or underlying conditions can exacerbate sleep issues. Since you mentioned experiencing gastrointestinal symptoms related to autonomic nervous system dysregulation, it’s possible that anxiety related to these symptoms could also be impacting your sleep quality.

To help improve your sleep, consider implementing good sleep hygiene practices. Here are some strategies that may assist you:
1. Maintain a Consistent Sleep Schedule: Go to bed and wake up at the same time every day, even on weekends. This helps regulate your body's internal clock.

2. Create a Relaxing Bedtime Routine: Engage in calming activities before bed, such as reading, taking a warm bath, or practicing relaxation techniques like deep breathing or meditation.

3. Limit Screen Time: Avoid screens (phones, tablets, TVs) at least an hour before bed, as the blue light emitted can interfere with melatonin production and disrupt your sleep cycle.

4. Optimize Your Sleep Environment: Ensure your bedroom is conducive to sleep—dark, quiet, and cool. Consider using earplugs, eye masks, or white noise machines if necessary.

5. Be Mindful of Food and Drink: Avoid large meals, caffeine, and alcohol close to bedtime, as these can disrupt sleep.

6. Physical Activity: Regular exercise can help improve sleep quality, but try to avoid vigorous workouts close to bedtime.

7. Limit Naps: If you find that napping during the day affects your nighttime sleep, consider limiting or eliminating naps.

8. Seek Professional Guidance: Since you are already seeing a doctor, continue to communicate openly about your symptoms. If your current medications (like Meizhu and Dongjian) are not providing relief, your doctor may consider adjusting your treatment plan or exploring other therapeutic options.

In terms of recovery, while it can be frustrating, many individuals do eventually return to a more normal sleep pattern after a period of adjustment. It may take several months, but with the right support and strategies, improvement is possible. If you continue to struggle, consider discussing the possibility of cognitive-behavioral therapy for insomnia (CBT-I) with your healthcare provider, as it has been shown to be effective for many individuals dealing with sleep issues.

Lastly, it’s crucial to avoid self-medicating or returning to benzodiazepines without medical supervision, as this can lead to a cycle of dependency. Stay in close contact with your healthcare provider to monitor your progress and make necessary adjustments to your treatment plan. Remember, you are not alone in this, and with time and the right approach, you can work towards restoring your sleep.

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