Managing Inflammation: Concerns About Medications Before PRP Therapy - Rehabilitation

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Proliferative treatment and issues with anti-inflammatory medications?


Hello, doctor.
I previously injured my coccyx and have an old injury.
I have an appointment with the rehabilitation department for PRP treatment.
The educational article mentioned that I should temporarily avoid anti-inflammatory medications, but I would like to ask if it's okay to apply them to other areas.
I previously saw a urologist and was prescribed a steroid ointment for inflammation; will using that affect my treatment? Also, will taking traditional Chinese medicine have any impact? I initially consulted for inflammation issues in the urology department; do I need to stop taking those medications? Thank you, doctor.

Niming, 20~29 year old female. Ask Date: 2021/11/22

Dr. Li Yanheng reply Rehabilitation


In principle, topical application should not have an impact.
It is recommended that you confirm with the physician who scheduled your treatment.
For the herbal medicine, please consult the Chinese medicine practitioner regarding the ingredients.

Reply Date: 2021/11/22

More Info


When preparing for Platelet-Rich Plasma (PRP) therapy, managing inflammation is crucial, as the effectiveness of the treatment can be influenced by the medications you are currently taking. PRP therapy is designed to promote healing by using your own platelets to stimulate tissue repair. However, the use of anti-inflammatory medications, including both oral and topical forms, can potentially interfere with this healing process.

1. Topical Steroids and Anti-Inflammatory Medications: You mentioned using a topical steroid ointment prescribed for inflammation in another area. While the application of topical steroids on a different body part may seem harmless, it is generally advisable to avoid any anti-inflammatory medications, including topical steroids, in the vicinity of the area being treated with PRP. This is because these medications can inhibit the inflammatory response that is necessary for the PRP to work effectively. The inflammatory response is a natural part of the healing process, and dampening it can reduce the efficacy of the PRP treatment.

2. Oral Medications: If you are taking oral anti-inflammatory medications, such as NSAIDs (non-steroidal anti-inflammatory drugs), it is recommended to discontinue these at least a week before your PRP therapy. This allows your body to return to a more natural inflammatory state, which is beneficial for the PRP to exert its healing effects. If you are on other medications, such as those for urinary tract inflammation, you should consult your healthcare provider about whether these need to be paused before your PRP treatment.

3. Herbal or Traditional Medicines: You also inquired about the use of traditional Chinese medicine or herbal remedies. While some herbal medications can have anti-inflammatory properties, others may not affect inflammation in the same way as conventional medications. It is essential to discuss any herbal supplements you are taking with your healthcare provider. They can help determine if these might interfere with your PRP therapy or if they should be stopped prior to the procedure.

4. Consultation with Your Healthcare Provider: Given your history of a coccyx injury and the ongoing treatment for urinary tract inflammation, it is crucial to have a thorough discussion with your healthcare provider or the physician performing the PRP therapy. They can provide personalized advice based on your medical history, current medications, and the specific area being treated. They may also suggest alternative pain management strategies that do not interfere with the PRP treatment.

5. Post-PRP Care: After the PRP therapy, you may be advised to avoid anti-inflammatory medications for a certain period to allow the treatment to take full effect. Your healthcare provider will give you specific instructions on how to manage pain and inflammation post-treatment.

In summary, while it might be tempting to use topical steroids or other anti-inflammatory medications to manage discomfort, it is generally best to avoid them in the area being treated with PRP. Always consult with your healthcare provider regarding any medications or supplements you are taking to ensure they do not interfere with your treatment. This careful management will help maximize the benefits of your PRP therapy and promote optimal healing.

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