HPV Vaccine Injection: Common Reactions and Antibody Testing - Urology

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HPV vaccination?


I received the first dose of the nine-valent HPV vaccine yesterday, and I experienced no discomfort at all (including at the injection site).
I am just curious because during the injection, I heard a sound similar to air and water being mixed and expelled.
After removing the cotton ball, there were no blood spots left, unlike what I experienced with the previous COVID-19 vaccine.
I would like to ask the doctor the following questions: 1.
Are these phenomena normal after the injection? 2.
If I complete all three doses, can I have my antibody levels tested? Thank you, doctor, for taking the time to read this!

Mr. Wang, 20~29 year old female. Ask Date: 2022/01/11

Dr. Sun Hongshun reply Urology


Hello Mr.
Wang: 1.
This phenomenon can occur, so there is no need to worry; it indicates that the nurse who administered your injection has excellent skills.
2.
You can have your antibodies tested.

Reply Date: 2022/01/11

More Info


The HPV vaccine, particularly the nine-valent Gardasil vaccine, is a crucial tool in preventing human papillomavirus (HPV) infections, which can lead to various cancers, including cervical cancer. It's great to hear that you've received your first dose of the vaccine and are curious about the injection process and subsequent antibody testing.

1. Injection Reactions: It's entirely normal to experience a range of reactions after receiving a vaccine. The sound you heard during the injection, which resembled air and water mixing, is not uncommon. This could be attributed to the technique used by the healthcare provider during the injection. If the injection site is not sore or swollen, and you did not experience any adverse reactions, it indicates that the procedure was performed correctly. The absence of blood spots or bruising is also a positive sign, suggesting that the needle was inserted properly and that there was no damage to blood vessels.

2. Antibody Testing After Completion of the Vaccine Series: After completing the full series of the HPV vaccine (which typically consists of three doses), it is indeed possible to test for antibodies. However, routine antibody testing is not commonly recommended or necessary for the general population. The vaccine is designed to stimulate your immune system to produce antibodies against the HPV types it targets, and clinical studies have shown that the vaccine is effective in generating a robust immune response.
If you are considering antibody testing, it’s essential to discuss this with your healthcare provider. They can provide guidance on whether testing is appropriate for you and what the results might indicate. Generally, a positive antibody test would suggest that your body has mounted an immune response to the vaccine, but it does not necessarily indicate whether you are protected against HPV or if you have been exposed to the virus in the past.

In summary, your experience with the HPV vaccine injection sounds typical, and the absence of discomfort is a good sign. If you have any concerns about the vaccine or its effects, or if you are considering antibody testing, it’s always best to consult with your healthcare provider for personalized advice. They can help clarify any doubts and ensure that you are on the right track for your health. Remember, the HPV vaccine is a significant step in protecting yourself against HPV-related diseases, and completing the vaccination series is crucial for optimal protection.

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