Esophageal Injury: Causes of Chest Pain After Medication - Gastroenterology and Hepatology

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Experiencing stomach pain and esophageal pain after taking medication?


Hello, I have a question.
I took anti-inflammatory and pain relief medication for a dental issue, and after one day, I experienced stomach pain.
The pharmacy then provided me with stomach medication, but after taking it, I developed a headache.
The pharmacy helped me switch medications, but after finishing two packets, I woke up in the middle of the night with stomach pain and difficulty swallowing.
I suspect I may have drug-induced esophageal or gastric injury.
Now, on the third day, my stomach feels somewhat better, but when I eat, I still experience a sensation of choking as the food passes through the esophagus, along with pain in the right sternum area.
Additionally, the pain beneath the right side of the sternum has become more pronounced.
Can an esophageal injury also cause pain beneath the right side of the sternum? Thank you!

SARA, 30~39 year old female. Ask Date: 2022/01/15

Dr. Chen Shidian reply Gastroenterology and Hepatology


Esophageal irritation or damage may be caused by anti-inflammatory medications.
A semi-liquid or lukewarm diet should be observed.
It is essential to drink enough water when swallowing medications.

Reply Date: 2022/01/15

More Info


Esophageal injury can indeed lead to chest pain, particularly in the context of medication use. The symptoms you are experiencing, including difficulty swallowing, chest pain, and discomfort in the right side of your chest, may be related to esophageal irritation or injury caused by the medications you have taken.
When medications, especially non-steroidal anti-inflammatory drugs (NSAIDs) or certain antibiotics, are ingested, they can sometimes cause irritation to the esophagus. This irritation can manifest as inflammation, leading to symptoms such as pain during swallowing (dysphagia), a burning sensation (heartburn), or even sharp pain that may radiate to the chest area. The esophagus is a muscular tube that connects the throat to the stomach, and any injury or inflammation in this area can cause referred pain, which may be felt in the chest or back.

In your case, the combination of anti-inflammatory and pain medications, along with the subsequent use of gastric medications, may have contributed to the irritation of your esophagus. It is important to note that swallowing pills without adequate water can increase the risk of esophageal injury, as the pill may become lodged in the esophagus, causing localized damage. This could explain the sensation of food getting stuck and the pain you are experiencing.

The right-sided chest pain you mentioned could also be related to esophageal injury. The esophagus runs along the spine and can cause pain that radiates to different areas of the chest, including the right side. Additionally, if there is any inflammation or irritation in the esophagus, it could potentially lead to muscle spasms or referred pain in the chest area.

To manage your symptoms, it is advisable to adopt a soft, bland diet that is easy to swallow. Avoiding spicy foods, acidic foods, and caffeine can also help reduce irritation. Staying hydrated and ensuring that you take medications with plenty of water can minimize the risk of further esophageal injury. If your symptoms persist or worsen, it is crucial to seek medical attention. A healthcare provider may recommend further evaluation, such as an endoscopy, to assess the condition of your esophagus and rule out any serious complications.

In summary, esophageal injury can indeed lead to chest pain, and the symptoms you are experiencing may be a result of the medications you have taken. It is essential to monitor your symptoms closely and consult with a healthcare professional if they do not improve. Proper management and care can help alleviate your discomfort and promote healing.

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