Managing Insomnia After Discontinuing Lorazepam: Seeking Solutions - Psychiatry

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I have been prescribed Lexotan for gastric pain due to autonomic nervous system disorder, but I still have insomnia after stopping the medication. What should I do?


Due to autonomic nervous system dysfunction, I have been experiencing stomach pain and have been taking Lorazepam for over three months at a dosage of 0.5 mg before bedtime.
After discontinuing the medication, I developed insomnia (which I did not have before taking it).
I have now been off the medication for six months and have been experiencing insomnia for the entire duration.
The insomnia is not caused by my autonomic nervous system dysfunction, as my only symptoms related to that are stomach pain, nausea, and a desire to vomit.
Interestingly, after stopping Lorazepam, my stomach pain symptoms have significantly decreased.
Before taking Lorazepam, I never had issues with insomnia.
The doctor who initially prescribed Lorazepam told me that it would be fine to take it for life.
However, my current doctor is puzzled by my symptoms and does not understand why the previous doctor recommended long-term use of Lorazepam.
He mentioned that there are many alternative medications available.
I am concerned about how long the insomnia after stopping the medication will last.
I tapered off the medication over three weeks before stopping completely, and I wonder if that was too quick.
I have tried various medications since then, but I can only sleep for 2 to 3 hours before waking up.
Although I can lie down and fall back asleep, I feel increasingly fatigued and lack energy during the day.
Currently, I am taking half a dose of Mirtazapine and one dose of Tianeptine, but my sleep remains poor.
I am uncertain how long it will take to return to my previous state.
I have read online that discontinuing medication can lead to poor sleep in the latter half of the night and that this could potentially last for months or even years.
Seeing this information makes me anxious about how much longer I can endure this or if I should resume taking Lorazepam.
If I go back to it, will it help? My current doctor does not recommend resuming Lorazepam, but my sleep issues persist despite trying different medications, and I am unsure of what to do.
I hope the doctor can provide some answers, and I would be very grateful.

Xiao Hao, 30~39 year old female. Ask Date: 2022/02/11

Dr. Yan Congyou reply Psychiatry


Hello: Based on your situation, it is recommended to combine other treatments for autonomic nervous system disorders, such as serotonin reuptake inhibitors.
Additionally, insomnia is one of the symptoms of autonomic nervous system dysregulation and needs to be treated concurrently.
If the appropriate medications are administered, symptoms can improve.

Reply Date: 2022/02/11

More Info


Managing insomnia after discontinuing Lorazepam can be a challenging and frustrating experience, especially when the underlying issues are complex and multifaceted. It’s clear from your description that you have been through a significant amount of distress related to your sleep patterns and overall well-being. Here’s a comprehensive approach to understanding your situation and exploring potential solutions.

Firstly, it’s important to recognize that Lorazepam, a benzodiazepine, is often prescribed for anxiety and sleep disorders. While it can be effective in the short term, long-term use can lead to dependence and withdrawal symptoms, including insomnia. The fact that you experienced insomnia after discontinuing Lorazepam suggests that your body may have developed a reliance on the medication to regulate sleep. This is not uncommon, and many individuals face similar challenges when tapering off benzodiazepines.

Your current symptoms of insomnia, where you can only sleep for 2-3 hours at a time, are indicative of a condition known as sleep maintenance insomnia. This can be exacerbated by anxiety, stress, or even the psychological impact of having previously relied on medication for sleep. It’s also worth noting that the discontinuation of Lorazepam may have led to a rebound effect, where the original symptoms of insomnia return more intensely after stopping the medication.

Given your situation, here are several strategies and considerations that may help you manage your insomnia:
1. Consult a Sleep Specialist: Since you have been experiencing persistent insomnia for six months, it may be beneficial to consult a sleep specialist. They can conduct a thorough evaluation, including a sleep study, to determine any underlying sleep disorders that may be contributing to your insomnia.

2. Cognitive Behavioral Therapy for Insomnia (CBT-I): This is a highly effective treatment for chronic insomnia. CBT-I focuses on changing the thoughts and behaviors that contribute to sleep problems. It can help you develop healthier sleep habits and address any anxiety related to sleep.

3. Gradual Medication Adjustment: If your current physician is hesitant to reintroduce Lorazepam, discuss the possibility of other medications that may help with sleep without the same risk of dependence. Options such as melatonin, certain antidepressants (like Mirtazapine), or non-benzodiazepine sleep aids (like Zolpidem) may be considered. However, these should be prescribed and monitored by a healthcare professional.

4. Lifestyle Modifications: Implementing good sleep hygiene practices can significantly improve sleep quality. This includes maintaining a consistent sleep schedule, creating a relaxing bedtime routine, limiting screen time before bed, and ensuring your sleep environment is conducive to rest (dark, quiet, and cool).

5. Mindfulness and Relaxation Techniques: Practices such as mindfulness meditation, yoga, or deep breathing exercises can help reduce anxiety and promote relaxation, making it easier to fall asleep and stay asleep.

6. Patience and Support: Recovery from medication dependence and the re-establishment of normal sleep patterns can take time. It’s essential to be patient with yourself and seek support from friends, family, or support groups who understand what you’re going through.

7. Regular Follow-ups: Keep an open line of communication with your healthcare provider. Regular follow-ups can help track your progress and make necessary adjustments to your treatment plan.

In conclusion, while the prospect of returning to Lorazepam may seem appealing due to your current struggles with insomnia, it’s crucial to weigh the potential risks and benefits. Engaging in a comprehensive treatment plan that includes behavioral therapy, lifestyle changes, and possibly alternative medications may provide a more sustainable solution to your insomnia. Remember, recovery is a journey, and seeking professional guidance is key to finding the right path for you.

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