Choosing Probiotics for Allergies and Ankylosing Spondylitis in Young Adults

Selection of Probiotics for Stiffness

Hello, Doctor.
My child is 20 years old and has had allergic issues with the nose and eyes (allergic conjunctivitis) since childhood.
They have now been diagnosed with ankylosing spondylitis.
Both the allergist and the rheumatologist have suggested taking probiotics.
I would like to ask:
1.
What specific strains of probiotics are recommended for allergies and ankylosing spondylitis, respectively? Or is it unnecessary to take probiotics?
2.
If probiotics are still recommended, can they be taken daily on a long-term basis? Or is it better to take them for a period of time and then take a break (for how long?) before continuing?
3.
After taking a specific strain of probiotics for a period (e.g., six months), is it advisable to switch to a different strain, or is it acceptable to continue with the same one?
Thank you for your assistance.

Zheng Zhen, 50~59 year old female. Ask Date: 2022/03/27

Dr. Gao Jiankai reply Internal Medicine

Hello, thank you for your question.
Currently, the relationship between probiotics, allergies, and ankylosing spondylitis is still in the research phase.
It is generally believed that changes in the gut microbiome may be related to the worsening or improvement of diseases; however, there is no clear evidence yet to prove that taking probiotics, which specific probiotics to take, or even the frequency of probiotic intake can treat or assist in the treatment of ankylosing spondylitis.
I believe that taking probiotics does not have any significant downsides, but it is important to compare options and be cautious of marketing claims to avoid unnecessary expenses.
The Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare, cares about your health.

Reply Date: 2022/03/27

More Info

When considering the use of probiotics for managing allergies and ankylosing spondylitis (AS) in young adults, it is essential to understand the role of probiotics in the immune system and their potential benefits for these conditions.
1. Recommended Probiotic Strains: For allergies, particularly allergic conjunctivitis, certain strains of probiotics may help modulate the immune response. Strains such as *Lactobacillus rhamnosus* GG and *Bifidobacterium lactis* have been studied for their potential to reduce allergic symptoms by enhancing gut health and influencing systemic immune responses. For ankylosing spondylitis, while the evidence is still emerging, probiotics like *Lactobacillus plantarum* and *Bifidobacterium bifidum* may help in managing inflammation and improving gut microbiota, which can be beneficial since gut health is increasingly recognized as playing a role in autoimmune conditions.

2. Long-term Use of Probiotics: Probiotics can generally be taken daily, and many studies support their long-term use without significant adverse effects. However, it is advisable to monitor the individual’s response to probiotics. Some healthcare providers recommend taking probiotics continuously, while others suggest cycling them—taking them for a few months, then pausing for a month or so before resuming. This approach can help maintain the effectiveness of the probiotics and prevent the body from becoming too accustomed to a specific strain.

3. Switching Probiotic Strains: After a prolonged period of taking a specific probiotic strain (such as six months), it may be beneficial to switch to another strain. This can help diversify the gut microbiome and potentially enhance the overall effectiveness of the probiotic regimen. However, it is not strictly necessary to switch strains if the individual is responding well to the current probiotic. The decision to change strains should be based on the individual's health status, response to treatment, and any new symptoms or changes in their condition.

In summary, probiotics can be a valuable adjunct in managing allergies and ankylosing spondylitis, but the choice of strains, duration of use, and whether to switch strains should be tailored to the individual’s specific needs and responses. It is always best to consult with a healthcare provider who can provide personalized recommendations based on the latest research and the individual’s health history. Regular follow-ups can help assess the effectiveness of the probiotics and make necessary adjustments to the treatment plan.

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