Why Stopping Lorazepam Led to Persistent Insomnia: A Patient's Journey - Psychiatry

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Why does someone who originally did not have insomnia experience it after stopping medication?


I previously took Lorazepam 0.5 mg for over three months, and stopping the medication has caused insomnia.
It has been over nine months since I stopped, and while I can fall asleep quickly, I wake up after 2 to 3 hours and then return to sleep, which is always light and leaves me feeling increasingly fatigued.
The reason I was prescribed Lorazepam was that my doctor said my stomach pain was caused by autonomic nervous system dysfunction.
I started taking Lorazepam due to my stomach pain, and before that, I never had insomnia.
I am unsure how long it will take to return to my previous state.
During this time, I switched to a different clinic and tried many non-benzodiazepine medications, but none were effective.
Initially, my doctor did not recommend going back to benzodiazepines, but he said I was suffering too much and prescribed them as a backup.
However, I have resisted taking them and have only used 25 mg of Trazodone, half a tablet.
I have read some information online stating that stopping medication can lead to poor sleep in the second half of the night, and it may even be persistent for months or years.
Seeing this makes me unsure how much longer I can endure this or if I really need to return to Lorazepam or other benzodiazepines.
I hope the doctor can provide me with some answers; I would be very grateful.

Xiao Cheng, 30~39 year old female. Ask Date: 2022/05/04

Dr. Yu Quanxun reply Psychiatry


Hello, based on your description in the letter, you are experiencing stomach pain and autonomic nervous system dysfunction.
You have previously taken Lexapro but stopped the medication, and you are currently troubled by sleep issues, worrying that they may be a result of discontinuing the medication.
Generally, with the assistance of a physician, a gradual and gentle adjustment of medication should yield good results.
Autonomic nervous system dysfunction and insomnia are common modern ailments, and most patients see significant improvement in their symptoms and quality of life with regular medical treatment.
I recommend that you consult with a psychiatrist to discuss your situation and schedule regular follow-up appointments to adjust your medication.
Thank you for your letter.

Reply Date: 2022/05/04

More Info


The journey of stopping Lorazepam, particularly after a prolonged use, can be challenging and often leads to persistent insomnia, as you've experienced. Lorazepam is a benzodiazepine that is commonly prescribed for anxiety and sleep disorders. While it can be effective in the short term, long-term use can lead to dependence and withdrawal symptoms, including insomnia.

When you stopped taking Lorazepam after three months of use, your body likely experienced withdrawal symptoms. Benzodiazepines can alter the brain's chemistry, and when the medication is suddenly discontinued, the brain may struggle to regain its natural balance. This can lead to a rebound effect, where the original symptoms (in your case, insomnia) return, often more intensely than before. The duration of these withdrawal symptoms can vary significantly from person to person. Some individuals may find that their sleep improves within weeks, while others, like yourself, may experience persistent insomnia for months or even longer.

Your experience of falling asleep quickly but waking up after a few hours and feeling increasingly fatigued is not uncommon among those who have stopped using benzodiazepines. This fragmented sleep can be attributed to the brain's adjustment to the absence of the drug, which previously helped regulate sleep patterns. Additionally, the anxiety and stress associated with your ongoing insomnia can further exacerbate sleep disturbances.

It's important to consider that the underlying issues that led to the prescription of Lorazepam, such as anxiety or autonomic nervous system dysregulation, may still be present. This could contribute to your current sleep difficulties. While you mentioned that your previous doctor prescribed Lorazepam for stomach pain related to autonomic dysfunction, it’s crucial to address both the physical and psychological aspects of your condition.

You’ve also explored various non-benzodiazepine medications, but it seems they haven't provided the relief you were hoping for. This can be frustrating, especially when dealing with chronic insomnia. It’s worth noting that finding the right treatment can be a process of trial and error, and what works for one person may not work for another.

Regarding your concerns about returning to Lorazepam or other benzodiazepines, it's essential to weigh the potential benefits against the risks of dependence and withdrawal. While these medications can provide immediate relief, they may not be the best long-term solution, especially if you are concerned about the possibility of becoming reliant on them again.

Cognitive Behavioral Therapy for Insomnia (CBT-I) is a highly effective non-pharmacological treatment for chronic insomnia. It focuses on changing the thoughts and behaviors that contribute to sleep difficulties. Techniques may include sleep hygiene education, stimulus control therapy, and cognitive restructuring. Engaging in CBT-I could provide you with tools to manage your insomnia without relying on medication.

Additionally, you mentioned considering rTMS (repetitive Transcranial Magnetic Stimulation), which is a non-invasive treatment that has shown promise in treating depression and anxiety. While research is still ongoing, some studies suggest that rTMS may also help improve sleep quality in individuals with insomnia, particularly when related to mood disorders.

In conclusion, while the journey of overcoming insomnia after stopping Lorazepam can be daunting, there are various avenues to explore. It’s crucial to maintain open communication with your healthcare provider, who can help guide you through this process. They may recommend a combination of therapies, including CBT-I, rTMS, and possibly a careful re-evaluation of medication options if necessary. Remember, recovery takes time, and it’s important to be patient with yourself as you navigate this challenging period.

Similar Q&A

Understanding Insomnia After Stopping Lorazepam: Causes and Solutions

I previously took Lorazepam 0.5 mg for over three months, and after stopping the medication, I have been experiencing insomnia for more than nine months. I can fall asleep quickly, but I wake up after 1 to 3 hours, and when I go back to sleep, it is very light sleep, making me fe...


Dr. Lin Mianzhang reply Psychiatry
Hello, Xiao Cheng: Thank you for your hard work! It seems that your current insomnia may be a symptom of medication withdrawal. I recommend a gradual tapering approach to discontinue the medication, such as first reducing Lorazepam to half a tablet. If you can maintain stable sle...

[Read More] Understanding Insomnia After Stopping Lorazepam: Causes and Solutions


Understanding Insomnia After Stopping Lorazepam: Causes and Solutions

I previously took Lorazepam 0.5 mg for over three months, and stopping the medication has caused insomnia for more than nine months. I can fall asleep quickly, but I wake up after 2 to 3 hours, and when I go back to sleep, it’s always light sleep, making me feel increasingly fati...


Dr. Yu Quanxun reply Psychiatry
Hello, based on your description in the letter, you are experiencing stomach pain and autonomic nervous system dysfunction. You have previously taken Lexapro but have since discontinued it, and you are currently troubled by sleep issues, worrying that they may be a result of stop...

[Read More] Understanding Insomnia After Stopping Lorazepam: Causes and Solutions


Understanding Insomnia After Stopping Lorazepam: Causes and Solutions

I previously took Lorazepam 0.5 mg for over three months, and stopping the medication has caused insomnia that has lasted for more than nine months. I can fall asleep quickly, but I wake up after 2 to 3 hours, and when I go back to sleep, it's only light sleep, making me fee...


Dr. Wang Yaoting reply Psychiatry
Hello: The dosage of Lorazepam 0.5 mg that you previously took is considered quite low. This dosage primarily provides anxiolytic effects and should not lead to significant or prolonged withdrawal symptoms. Insomnia may be related to your underlying condition or circadian rhythm ...

[Read More] Understanding Insomnia After Stopping Lorazepam: Causes and Solutions


Understanding Insomnia After Stopping Lorazepam: Causes and Solutions

I previously took Lorazepam 0.5 mg for over three months, and after stopping the medication, I have been experiencing insomnia for over nine months. I can fall asleep quickly, but I wake up after 2 to 3 hours, and when I go back to sleep, it's only light sleep, making me fee...


Dr. Wu Enliang reply Psychiatry
It may be advisable for users to consider using longer-acting benzodiazepines such as Clonazepam or Diazepam instead of Lorazepam, as they may facilitate easier discontinuation (but this should still be discussed with your physician), and to enhance sleep hygiene. Dr. Wu En-Liang...

[Read More] Understanding Insomnia After Stopping Lorazepam: Causes and Solutions


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