Managing Blood Pressure Medication: Concerns and Solutions for Hypertension - Cardiology

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Blood pressure medication issues?


Hello Doctor: I have had high blood pressure for about 6 years, and I have been controlling it with Amlodipine 80/5, maintaining levels between 120-130/80-90.
Recently, one day my blood pressure suddenly rose to 170/94.
After taking my usual blood pressure medication between 8-10 AM, my blood pressure would spike again in the afternoon to 140-150/80-85, accompanied by a feeling of heat in my head.
I later visited the hospital and was prescribed Nebivolol 5 mg.
I have a few questions: 1.
Why was my original blood pressure medication able to control my levels throughout the day, but now it is not effective? What should I do? 2.
How long does Nebivolol last, and can it be used in conjunction with my original blood pressure medication? 3.
How should I manage my current situation? It is really troubling me.
Thank you, Doctor.

Běijí xióng, 40~49 year old female. Ask Date: 2022/06/04

Dr. Chen Jili reply Cardiology


It is advisable for you to discuss the above situation further with your attending physician.
Thank you, and wishing you good health!

Reply Date: 2022/06/04

More Info


Managing hypertension can be a complex process, especially when medications that previously worked well begin to lose their effectiveness. Your situation, where your blood pressure has recently spiked despite ongoing treatment, raises several important considerations.

1. Why is my blood pressure medication no longer effective?
There are several reasons why a medication that once controlled your blood pressure may become less effective over time. One possibility is that your body may develop a tolerance to the medication, meaning that the same dose no longer produces the desired effect. Additionally, changes in your lifestyle, diet, stress levels, or even weight can influence blood pressure. Other factors such as hormonal changes, the onset of other medical conditions, or even medication interactions can also play a role. It's essential to communicate these changes to your healthcare provider, as they may need to adjust your treatment plan.

2. What is the duration of Nebivolol (耐比洛) and can it be used with my current medication?
Nebivolol is a beta-blocker that is often used to treat high blood pressure. It typically has a duration of action of about 24 hours, which means it can be taken once daily. It is generally safe to use Nebivolol in conjunction with other antihypertensive medications, but this should always be done under the guidance of your healthcare provider. Combining medications can sometimes enhance blood pressure control, but it also increases the risk of side effects, so careful monitoring is necessary.

3. How should I manage my current situation?
Given your recent blood pressure readings and the accompanying symptoms, it is crucial to take a proactive approach. Here are some steps you can consider:
- Monitor Your Blood Pressure Regularly: Keep a log of your blood pressure readings at different times of the day. This information can help your doctor determine if your medication needs adjustment.


- Lifestyle Modifications: Continue to focus on a heart-healthy lifestyle. This includes maintaining a balanced diet low in sodium, engaging in regular physical activity, managing stress, and avoiding tobacco and excessive alcohol consumption. These changes can significantly impact blood pressure control.


- Consult Your Doctor: Schedule an appointment with your healthcare provider to discuss your recent blood pressure spikes and the addition of Nebivolol. They may want to adjust your medication regimen or investigate other underlying causes for your elevated blood pressure.


- Be Aware of Symptoms: If you experience symptoms such as severe headaches, shortness of breath, or chest pain, seek medical attention immediately. These could be signs of a hypertensive crisis or other serious conditions.

In conclusion, managing hypertension is often a dynamic process that requires regular monitoring and adjustments to treatment. It's essential to maintain open communication with your healthcare provider and to be proactive about your health. By doing so, you can work together to find the most effective strategy for controlling your blood pressure and improving your overall well-being.

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