the Differences Between Pharmacy and Clinic A-Retinoids - Dermatology

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I would like to know the difference between A acid from a pharmacy and that from a clinic?


Hello, doctor.
I previously visited a dermatologist for about two years due to acne and learned about topical retinoids, which have been a game changer for me.
After using it for two years, my skin has improved significantly, and I no longer have any acne.
I am still using a topical retinoid as a preventive measure.
However, the clinic is really far from my home, and there is a chain pharmacy less than 30 meters away.
I would like to know if I can buy 0.1% topical retinoid from the pharmacy without any serious skin conditions and considering the pandemic, I am hesitant to visit the clinic.
Is it legal to purchase it from the pharmacy, or is the prescription topical retinoid from the clinic more potent and not recommended for self-purchase at the pharmacy?

Qianshuiyuan, 20~29 year old female. Ask Date: 2022/06/11

Dr. Wu Yuxin reply Dermatology


It is the same.

Reply Date: 2022/06/11

More Info


When it comes to the treatment of acne, particularly with topical retinoids like Tretinoin and Azelaic Acid, understanding the differences between pharmacy and clinic prescriptions is crucial for effective management of your skin condition.
Tretinoin, a derivative of Vitamin A, is commonly prescribed for acne due to its ability to promote cell turnover, prevent clogged pores, and reduce inflammation. It is often considered a first-line treatment for moderate to severe acne. On the other hand, Azelaic Acid is a naturally occurring acid that has antibacterial properties and helps to reduce inflammation and hyperpigmentation. It is generally milder than Tretinoin and can be a good option for those with sensitive skin or for individuals who may experience irritation from stronger retinoids.

In your case, if you have been using Tretinoin (often referred to as "A-Retinoids") and have seen significant improvement, it is understandable that you would want to continue using a topical treatment for maintenance. However, the question arises whether you can purchase a similar product over the counter at a pharmacy, especially if you are looking at a product like "痘膚潤" (which is likely a brand name for a topical retinoid or similar formulation).

In the United States, Tretinoin is classified as a prescription medication, meaning it should be obtained through a healthcare provider. This is primarily due to the potential side effects, including skin irritation, photosensitivity, and the need for proper guidance on usage. While Azelaic Acid is available over the counter in lower concentrations, Tretinoin typically requires a prescription because of its potency and the need for monitoring by a healthcare professional.

If you are considering using a product like "痘膚潤" without a prescription, it is essential to ensure that it is indeed a product that is safe and appropriate for your skin type. While some pharmacies may carry lower-strength retinoids or similar products, they may not have the same efficacy as prescription-strength Tretinoin. Additionally, using a product without proper guidance could lead to adverse effects, especially if you have a history of sensitive skin or have experienced irritation in the past.

Regarding legality, in most jurisdictions, it is not illegal to purchase over-the-counter products that are not classified as controlled substances. However, using prescription medications without a prescription can lead to complications, especially if the product is not suitable for your skin type or if you experience adverse reactions.
In conclusion, while it may be tempting to seek out a topical retinoid at a nearby pharmacy for convenience, it is advisable to consult with your dermatologist before making any changes to your treatment regimen. They can provide you with the best advice tailored to your skin's needs and help you determine whether an over-the-counter product is appropriate or if a prescription is necessary. Always prioritize safety and efficacy when it comes to your skincare, especially with potent ingredients like retinoids.

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