Managing High Cholesterol: Key Questions and Answers for Your Health - Family Medicine

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High cholesterol


Hello Doctor: Here are my two test reports, from February 2021 and July 2022:
Total cholesterol: 215, 226 (unit: mg/dL)
Triglycerides: 69, 126 (unit: mg/dL)
HDL-cholesterol: 36, 37 (unit: mg/dL)
LDL-cholesterol: 160, 164 (unit: mg/dL)
Total cholesterol/HDL: 6.0, 6.1
Total Bilirubin: 1.85, 1.2 (unit: mg/dL)
Glucose: 81, 99 (unit: mg/dL)
My basic information: Age: 35 years, Height: 165 cm, Weight: 80 kg.
My father had a myocardial infarction at age 68 and has a heart stent.

Here are my questions:
1.
Do I need to take medication?
2.
If medication is needed, should I take Crestor 10 mg or Crestor 5 mg?
3.
If my condition is controlled with medication, can I stop taking it, or will I need to take it for life?
4.
Based on the above reports, my total bilirubin and blood glucose are elevated; can I take Crestor 10 mg?
5.
I understand that medications can have side effects; given my situation, is the benefit of taking medication greater than the risk?
6.
If I start exercising seriously and eating healthily, how much can my LDL potentially decrease? Is there a chance it can return to the normal range?
7.
If medication is necessary, how often should I return for follow-up tests? Thank you!

rh, 30~39 year old female. Ask Date: 2022/07/11

Dr. Hou Angting reply Family Medicine


Hello: Based on the report and medical history you provided, although your current lipid levels have slightly increased, they are still not at the stage where medication is recommended.
It is advised that you reduce your calorie intake, increase your consumption of fruits and vegetables, engage in moderate exercise, and follow up annually at a family medicine clinic.
Wishing you good health.

Reply Date: 2022/07/11

More Info


Managing high cholesterol is a crucial aspect of maintaining cardiovascular health, especially considering your family history of heart disease. Based on the information you've provided, let's address your questions systematically.

1. Do you need medication?
Your total cholesterol levels of 215 mg/dL and 226 mg/dL are above the desirable range (less than 200 mg/dL). Your LDL cholesterol (often referred to as "bad" cholesterol) is also elevated at 160 mg/dL and 164 mg/dL, which is classified as borderline high. Given your family history of heart disease, particularly your father's myocardial infarction at a relatively young age, it would be prudent to consider medication, especially if lifestyle changes alone do not yield significant improvements.

2. If medication is needed, which dosage of Crestor should you take?
Crestor (rosuvastatin) is commonly prescribed to help lower LDL cholesterol. The appropriate dosage can vary based on individual factors, including the degree of cholesterol elevation and any other risk factors you may have. Generally, starting with 5 mg or 10 mg is common, but your healthcare provider will determine the best dose based on your specific situation and response to treatment.

3. Can you stop medication once cholesterol levels are controlled?
Cholesterol-lowering medications can be very effective, but they are often part of a long-term management strategy. If you achieve your target cholesterol levels through lifestyle changes and medication, your doctor may consider tapering off the medication. However, this should only be done under medical supervision, as stopping medication can lead to a rebound in cholesterol levels.

4. Can you take Crestor with elevated bilirubin and glucose levels?
While elevated bilirubin and glucose levels can indicate underlying health issues, they do not automatically preclude the use of Crestor. However, your healthcare provider will need to evaluate these levels in the context of your overall health and may monitor liver function tests more closely if you start on statin therapy.

5. Are the benefits of medication greater than the risks?
Statins, including Crestor, can have side effects, but for many individuals, the benefits of lowering LDL cholesterol and reducing the risk of heart disease outweigh the potential risks. Common side effects include muscle pain and liver enzyme elevations, but serious side effects are rare. Your doctor will assess your risk factors and overall health to determine if the benefits of starting a statin are greater than the risks in your case.

6. How much can lifestyle changes lower LDL cholesterol?
Adopting a heart-healthy lifestyle can significantly impact your cholesterol levels. Regular exercise, a diet rich in fruits, vegetables, whole grains, and healthy fats (like those found in fish and nuts), and weight management can lower LDL cholesterol by 5% to 20%. In some cases, individuals have successfully returned their LDL levels to the normal range through lifestyle modifications alone, but this varies widely.

7. How often should you follow up with your doctor?
If you start medication, your doctor will likely want to see you every 3 to 6 months initially to monitor your cholesterol levels and assess for any side effects. Once your levels are stable and well-controlled, follow-up appointments may be spaced out to once a year.

In summary, managing high cholesterol involves a combination of lifestyle changes and, if necessary, medication. Given your family history and current cholesterol levels, it is advisable to consult with your healthcare provider to create a tailored plan that addresses your specific needs and concerns. Regular monitoring and adjustments to your treatment plan will be key to achieving and maintaining optimal cholesterol levels.

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