Should You Continue Pain Relief Medication with Antibiotics? - Family Medicine

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Medication Use


Hello Director Liao: I am currently taking Ketorolac and antibiotics for a urinary tract infection.
I would like to ask if I can stop taking the anti-inflammatory pain reliever (Ketorolac) if the pain decreases, or is it necessary to complete the entire course of both the anti-inflammatory and the antibiotics? Thank you, Director Liao!

Yu Yuan, 20~29 year old female. Ask Date: 2022/08/24

Dr. Liao Yaopan reply Family Medicine


Hello, the treatment of infectious diseases primarily relies on antibiotics.
As for the prescription of Ketorolac given by the original physician, the indication or purpose is unclear.
The best approach would be to discuss this with the prescribing physician.
Please note: online consultations are not equivalent to in-person visits and cannot provide diagnoses or treatment recommendations.
Changhua Hospital cares about you.

Reply Date: 2022/08/24

More Info


When it comes to managing pain relief during a urinary tract infection (UTI) while on antibiotics, it's essential to understand the roles of both medications and how they can interact with each other. In your case, you are currently taking Ketorolac (Keta-Fu-Ning) for pain relief alongside antibiotics.
First, let's clarify the purpose of each medication. Antibiotics are prescribed to eliminate the bacterial infection causing the UTI. On the other hand, pain relief medications like Ketorolac are non-steroidal anti-inflammatory drugs (NSAIDs) that help alleviate pain and reduce inflammation. While these medications can be taken concurrently, their necessity depends on your symptoms and overall health status.

If you find that your pain has significantly decreased and is manageable, it may be appropriate to discontinue the pain relief medication. However, it is crucial to consider a few factors before making this decision:
1. Symptom Monitoring: If your pain has lessened but is not entirely gone, you may want to continue taking the pain relief medication until you are pain-free. Stopping it too early could lead to a resurgence of discomfort, which might affect your quality of life.

2. Antibiotic Course: It is generally recommended to complete the full course of antibiotics as prescribed, even if your symptoms improve. This is to ensure that the infection is fully eradicated and to prevent the development of antibiotic resistance. Pain relief medications can be adjusted based on your comfort level, but antibiotics should be taken as directed.

3. Consulting Your Physician: Always consult with your healthcare provider before making any changes to your medication regimen. They can provide personalized advice based on your specific situation, including the severity of your infection and your response to treatment.

4. Potential Side Effects: If you experience any adverse effects from either medication, such as gastrointestinal discomfort from NSAIDs or allergic reactions from antibiotics, inform your doctor immediately. They may suggest alternatives or adjustments to your treatment plan.

5. Underlying Conditions: If your pain persists or worsens despite treatment, it may indicate an underlying issue that needs further investigation. Conditions such as prostatitis or kidney stones can cause pain that mimics UTI symptoms, and your doctor may need to perform additional tests.

In summary, while it is generally acceptable to stop taking pain relief medication like Ketorolac if your pain has significantly decreased, it is essential to complete your antibiotic course. Always communicate with your healthcare provider about your symptoms and any changes in your medication regimen. They can help ensure that you are on the right path to recovery while managing your pain effectively.

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