Chronic Prostatitis: Treatment Challenges and Solutions - Urology

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Chronic prostatitis issues?


Hello Doctor, I have been suffering from chronic prostatitis for a year.
During this time, my semen culture has shown bacteria at times and at other times it has not.
The first culture revealed Enterococcus faecalis, and I was prescribed oral Norfloxacin, which was ineffective.
However, the administration of Suanbi via intravenous injection was effective, but the symptoms recurred the next day.
I subsequently had two more sterile tests, but the symptoms did not resolve, including perineal, anal, and genital pain, as well as frequent urination.
The third semen culture showed Klebsiella pneumoniae, and the doctor advised a three-month course of oral Ciprofloxacin.
After one month of treatment with no improvement, I consulted other doctors who had not heard of a three-month regimen and did not recommend it.
On my fourth visit, I changed doctors again, and the result was sterile.
The new doctor diagnosed me with sterile prostatitis and suggested I undergo shockwave therapy, costing 6,000 NT dollars per session for a total of six sessions.

My questions are:
1.
Is it possible for multiple bacterial strains to exist simultaneously? What is the accuracy of semen cultures, given the varying results? Is there a possibility that bacteria are hiding in the prostate and cannot be detected?
2.
It seems that the treatment for sterile prostatitis does not involve antibiotics.
Besides pain relievers, muscle relaxants, and alpha-blockers, are there any other medications that can treat this condition, focusing on a cure rather than just symptom management?
3.
Can shockwave therapy truly cure prostatitis or pelvic pain syndrome? After all, it is a significant financial investment.

Thank you, Doctor.
I feel truly at a loss.
The urologist even suggested I see a psychiatrist, which I have done.
Thank you.

030, 20~29 year old female. Ask Date: 2022/09/03

Dr. Li Xinyi reply Urology


Initially, it was Enterococcus faecalis.
Are there any issues related to anal intercourse or sexually transmitted infections (STIs)? The pathogens of STIs are often difficult to culture and diagnose, and if risky sexual behaviors continue, the problem may not be resolved.
I suspect there may be hidden infections that have not been detected, so it is essential to consult a urologist and discuss the situation in detail with a physician.

Reply Date: 2022/09/03

More Info


Chronic prostatitis, particularly nonbacterial prostatitis or chronic pelvic pain syndrome (CPPS), presents a significant challenge for both patients and healthcare providers. Your experience reflects the complexities and frustrations many face when dealing with this condition, especially when symptoms persist despite various treatments.


Understanding the Condition
Chronic prostatitis can manifest in different forms, and it is often categorized into inflammatory and non-inflammatory types. In your case, it seems you have been diagnosed with nonbacterial prostatitis, which can be particularly difficult to treat. The variability in bacterial cultures, where you sometimes find bacteria and other times do not, is not uncommon. This can be attributed to several factors, including the possibility of bacteria being present in low quantities or in biofilms, which are difficult to detect through standard culture methods.


Treatment Challenges
1. Bacterial Variability: The presence of different bacterial strains in your semen cultures suggests that there may be multiple bacterial species involved, or that some bacteria are not easily cultured. This can lead to inconsistent results and complicate treatment decisions. It's also possible that some bacteria are sequestered within the prostate tissue, evading detection.

2. Nonbacterial Prostatitis: For nonbacterial prostatitis, traditional antibiotic treatments are often ineffective. Instead, management focuses on symptom relief and addressing underlying factors. Medications such as pain relievers, muscle relaxants, and alpha-blockers can help alleviate symptoms, but they do not address the root cause of the condition.

3. Alternative Therapies: You mentioned the suggestion of shockwave therapy. This treatment has shown promise in some studies for alleviating chronic pelvic pain and prostatitis symptoms. However, its effectiveness can vary from person to person, and while some patients report significant relief, others may not experience the same benefits. It is essential to weigh the potential benefits against the costs and to discuss this thoroughly with your healthcare provider.


Recommendations for Management
1. Lifestyle Modifications: Maintaining a healthy lifestyle can significantly impact symptom management. Regular exercise, a balanced diet, and avoiding irritants such as caffeine, alcohol, and spicy foods may help reduce symptoms. Stress management techniques, including mindfulness and relaxation exercises, can also be beneficial.

2. Physical Therapy: Pelvic floor physical therapy can be an effective treatment for chronic pelvic pain. A trained physical therapist can help address muscle tension and dysfunction in the pelvic area, which may contribute to your symptoms.

3. Consider Multidisciplinary Approaches: Given the complexity of your symptoms, a multidisciplinary approach may be beneficial. This could involve collaboration between urologists, pain specialists, physical therapists, and mental health professionals. Addressing the psychological aspects of chronic pain is crucial, as anxiety and depression can exacerbate symptoms.

4. Follow-Up and Monitoring: Regular follow-ups with your healthcare provider are essential to monitor your condition and adjust treatment as necessary. If you feel that your current treatment plan is not effective, do not hesitate to seek a second opinion or explore other specialists who may have different insights or treatment options.


Conclusion
Chronic prostatitis is a multifaceted condition that often requires a comprehensive and individualized treatment approach. While it can be frustrating to deal with persistent symptoms, there are various strategies and therapies available that may help improve your quality of life. It's crucial to maintain open communication with your healthcare providers and advocate for your health, exploring all available options to find what works best for you.

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