Do Ankylosing Spondylitis Patients Need Antiviral Drugs for COVID-19? - Internal Medicine

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Do patients with ankylosing spondylitis who are diagnosed with COVID-19 need to take antiviral medication?


Hello Doctor, I am a patient with ankylosing spondylitis.
I would like to ask you: 1) If a patient with ankylosing spondylitis is diagnosed with COVID-19, what are the government's guidelines or recommendations regarding antiviral medications? 2) Are patients with ankylosing spondylitis considered a significant risk factor for COVID-19? Thank you, Doctor.

Hao, 20~29 year old female. Ask Date: 2022/10/05

Dr. Hong Yuanbin reply Internal Medicine


Hello, regarding the second risk factor, one of the conditions is diseases that affect immune function (such as HIV infection, congenital immunodeficiency, solid organ or hematopoietic stem cell transplantation, and the use of corticosteroids or other immunosuppressants).
Therefore, patients with ankylosing spondylitis who are taking related medications are indeed considered at risk.
Concerning the first point, it is recommended that patients with ankylosing spondylitis who are on these medications discuss with their physician whether their current condition is suitable for antiviral medication.
Thank you for your inquiry.

Reply Date: 2022/10/05

More Info


When it comes to the management of COVID-19 in patients with Ankylosing Spondylitis (AS), there are several important considerations to take into account. First, let's address your questions regarding antiviral medications and the classification of AS as a significant risk factor for severe COVID-19.

1. Antiviral Drug Guidelines for COVID-19 in AS Patients: The use of antiviral medications, such as Paxlovid or other similar agents, is generally recommended for patients who are at higher risk of developing severe illness from COVID-19. While the government may not have specific guidelines that classify Ankylosing Spondylitis as a high-risk condition, it is essential to consider the overall health status of the individual patient. If you are taking immunosuppressive medications or have other comorbidities, this may increase your risk for severe outcomes from COVID-19. Therefore, it is crucial to have a detailed discussion with your healthcare provider about your specific situation. They will evaluate your symptoms, medical history, and any medications you are currently taking to determine if antiviral therapy is appropriate for you.

2. Is Ankylosing Spondylitis a Significant Risk Factor for COVID-19?: Ankylosing Spondylitis itself is not universally classified as a significant risk factor for severe COVID-19. However, patients with AS may have an altered immune response due to the disease itself or the medications used to manage it, such as immunosuppressants. This altered immune response can potentially increase the risk of severe illness if infected with COVID-19. The Centers for Disease Control and Prevention (CDC) and other health authorities typically categorize individuals with underlying health conditions, including autoimmune diseases, as being at increased risk. Therefore, while AS alone may not be listed as a major risk factor, the context of your overall health and treatment regimen is critical.

Additional Considerations:
- Vaccination: It is highly recommended that individuals with Ankylosing Spondylitis receive COVID-19 vaccinations, as they can significantly reduce the risk of severe illness. While some patients may experience flares of their underlying condition post-vaccination, the benefits of vaccination in preventing severe COVID-19 far outweigh the risks.

- Monitoring Symptoms: If you do contract COVID-19, closely monitor your symptoms. If you experience worsening symptoms such as difficulty breathing, persistent chest pain, or confusion, seek medical attention immediately.
- Symptom Management: For mild cases of COVID-19, symptom management may be sufficient. Over-the-counter medications like acetaminophen (Tylenol) can help alleviate fever and body aches. However, these medications do not eliminate the virus; they merely help manage symptoms while your immune system works to clear the infection.

- Long COVID Considerations: There is ongoing research into the long-term effects of COVID-19, known as Long COVID. Patients with autoimmune conditions may be particularly concerned about these potential long-term effects. It is essential to discuss any lingering symptoms with your healthcare provider, as they can help guide you through management strategies.

In conclusion, while Ankylosing Spondylitis may not be explicitly listed as a significant risk factor for severe COVID-19, the individual patient's health status and treatment regimen play a crucial role in determining the need for antiviral medications. Always consult with your healthcare provider for personalized medical advice tailored to your specific circumstances.

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