Managing Medication for Ankylosing Spondylitis During COVID-19 - Internal Medicine

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Medication-related issues


Hello Doctor: I have ankylosing spondylitis, and I am currently taking 1000 mg of Celebrex daily.
I would like to ask you: 1) If I contract an infection, should I continue taking Celebrex? If I need to stop, how long should I refrain from taking it? 2) If I contract an infection, is it necessary to take Paxlovid? Thank you, Doctor.

Hao, 10~19 year old female. Ask Date: 2022/10/12

Dr. Zeng Guosen reply Internal Medicine


1.
If infected, you can continue taking Celecoxib.
2.
In your situation, Paxlovid may not be necessary.
Thank you for your question.

Reply Date: 2022/10/12

More Info


When managing medication for Ankylosing Spondylitis (AS) during a COVID-19 infection, there are several important considerations to keep in mind. As a patient with AS, you are likely on medications such as Salazopyrin (also known as Sulfasalazine), which is an immunomodulatory drug used to manage inflammation and pain associated with your condition.
1. Continuing Salazopyrin During COVID-19:
If you contract COVID-19, the decision to continue or pause your Salazopyrin treatment should be made in consultation with your healthcare provider. Generally, it is recommended that patients with autoimmune conditions continue their immunomodulatory therapies unless they experience severe illness or are advised otherwise by their physician. Stopping Salazopyrin abruptly can lead to a flare-up of your AS symptoms, which may complicate your overall health status during a COVID-19 infection. If your COVID-19 symptoms are mild and you are managing them at home, it is likely safe to continue taking Salazopyrin. However, if you develop more severe symptoms or complications, your doctor may recommend temporarily stopping the medication. The duration for which you might need to pause the medication would depend on your clinical condition and the guidance of your healthcare provider.

2. Use of Paxlovid:
Paxlovid is an antiviral medication that has been authorized for emergency use in treating mild to moderate COVID-19 in patients at high risk for progression to severe disease. Whether you need to take Paxlovid depends on several factors, including your age, overall health, and any underlying conditions that may increase your risk for severe COVID-19. As a 21-year-old with AS, your risk may be lower than older patients or those with more severe comorbidities. However, the immunomodulatory effects of Salazopyrin could potentially influence your immune response to COVID-19, which is why it’s crucial to discuss this with your healthcare provider. They will evaluate your specific situation and determine if Paxlovid is necessary based on your risk factors and the severity of your COVID-19 symptoms.

In summary, it is essential to maintain open communication with your healthcare provider regarding your AS treatment during a COVID-19 infection. They can provide personalized advice based on your health status and the latest clinical guidelines. Additionally, monitoring your symptoms closely and seeking medical attention if they worsen is crucial.
Furthermore, it is important to stay informed about the latest recommendations from health authorities regarding COVID-19 management, especially for individuals with underlying health conditions. Vaccination remains a key strategy in reducing the risk of severe illness from COVID-19, and discussing vaccination options with your rheumatologist can help you make informed decisions about your health moving forward.

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