Should Ankylosing Spondylitis Patients Take Antiviral Drugs for COVID-19? - Otolaryngology

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Should patients with ankylosing spondylitis who are diagnosed with COVID-19 take antiviral medications?


Hello Doctor, I would like to ask if the government has announced the major risk factors for COVID-19.
As a 21-year-old patient with ankylosing spondylitis who has tested positive for COVID-19, would you consider prescribing antiviral medication? Thank you, Doctor.

Jie, 20~29 year old female. Ask Date: 2022/10/05

Dr. Zheng Jueyi reply Otolaryngology


The use of antiviral medications requires comprehensive consideration from multiple aspects.
It is recommended to discuss in detail with the physician who confirmed the positive diagnosis before making a decision.

Reply Date: 2022/10/05

More Info


When it comes to the management of COVID-19 in patients with Ankylosing Spondylitis (AS), the decision to prescribe antiviral medications such as Paxlovid or other treatments should be made on a case-by-case basis, taking into account several factors.
Firstly, Ankylosing Spondylitis is a type of inflammatory arthritis that primarily affects the spine and can lead to severe, chronic pain and discomfort. Patients with AS may be on immunomodulatory medications, such as Salazopyrin (Salsalate), which can alter their immune response. While AS itself is not typically listed as a significant risk factor for severe COVID-19, the underlying condition and any medications that affect the immune system can influence the patient's overall risk profile.

In your case, being a 21-year-old patient with AS who has tested positive for COVID-19, it is essential to consider your current health status, the severity of your COVID-19 symptoms, and any other underlying health conditions. If you are experiencing mild symptoms, such as a dry cough and fatigue, and do not have any additional risk factors (like obesity, diabetes, or cardiovascular issues), your healthcare provider may assess that you can manage your symptoms without antiviral treatment.
However, if your symptoms worsen or if you have concerns about your immune system due to your AS or the medications you are taking, your doctor may recommend antiviral treatment. Antiviral medications like Paxlovid have been shown to reduce the severity of COVID-19 and the risk of hospitalization, especially when administered early in the course of the illness. The key is to start these medications as soon as possible after diagnosis, ideally within the first few days of symptom onset.

It's also important to discuss with your healthcare provider any potential side effects of antiviral medications, especially considering your current treatment for AS. While Paxlovid is generally well-tolerated, it can interact with other medications, and your doctor will consider these interactions when making a treatment decision.

In summary, whether or not to take antiviral drugs for COVID-19 as an Ankylosing Spondylitis patient depends on your individual health circumstances, the severity of your COVID-19 symptoms, and any other medications you may be taking. It is crucial to have an open and thorough discussion with your healthcare provider to weigh the risks and benefits of antiviral treatment in your specific situation. They will be able to provide personalized recommendations based on the latest clinical guidelines and your health history.

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