Reverse Ejaculation: Medication Effects and Prostate Health - Urology

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Hello, Director Du?


Recently, I asked the director a question, but now it seems to be caused by the side effects of the medication.
Before taking Alfuzosin, my ejaculation during masturbation was normal.
After starting the medication, I still have normal erections and can feel the sensation of ejaculation (I can feel the movement in the penis during ejaculation), but the semen has inexplicably disappeared.
After researching on Google, I found that this medication can cause retrograde ejaculation, but the sensation of urination is only slightly cloudy, with no white semen present.
It also states that retrograde ejaculation caused by this medication does not affect health.

Additionally, I have noticed a slight decrease in libido, but I generally have a high sex drive.
However, this medication has significantly reduced my impulsive feelings (there is a noticeable difference, possibly due to the lack of ejaculation, which gives a feeling of being in a state of zen and a sense of dissatisfaction from not being able to ejaculate, making me want to ejaculate even more).

I would like to ask if this medication is the most effective treatment for benign prostatic hyperplasia (BPH) and if it helps to reduce the size of the prostate.
I have seen that some medications have such effects, so how long should I take this medication to achieve results? After all, the doctor mentioned that at my age, my prostate is somewhat enlarged and needs early treatment! I also read that it seems that no matter how long this medication is taken, the side effects will disappear and return to normal once the medication is stopped.
Should I try to minimize masturbation frequency while on this medication until the doctor advises me to stop, or are there alternative medications available?

Mr. Chen, 30~39 year old female. Ask Date: 2022/10/12

Dr. Du Shixi reply Urology


Hello: This type of medication often has such effects.
If you are concerned, you can switch medications during your follow-up visit; some medications have fewer side effects.
As for the duration of use, it should be evaluated by your physician.
There is no need to specifically try to minimize the frequency of masturbation.
Wishing you good health.

Reply Date: 2022/10/12

More Info


Understanding reverse ejaculation and its relationship with medications, particularly those used to treat prostate issues, is crucial for men experiencing these symptoms. In your case, it seems that you are experiencing reverse ejaculation after starting a medication called 活路利淨 (likely referring to a medication like Alfuzosin or a similar alpha-blocker). This medication is commonly prescribed for benign prostatic hyperplasia (BPH), which is an enlargement of the prostate gland that can lead to urinary symptoms.

Reverse ejaculation occurs when semen is redirected into the bladder instead of being expelled through the urethra during ejaculation. This condition can be a side effect of certain medications, particularly those that affect the smooth muscle tone in the prostate and bladder neck. While it can be concerning, reverse ejaculation is generally not harmful to your health. It does not affect your ability to achieve orgasm or the pleasure associated with sexual activity, but it can lead to psychological discomfort, especially if you are accustomed to the physical sensation of ejaculation.

Regarding your concerns about the effectiveness of the medication for treating prostate enlargement, alpha-blockers like the one you are taking are indeed effective in relieving urinary symptoms associated with BPH. They work by relaxing the muscles in the prostate and bladder neck, making it easier to urinate. However, the time it takes to notice improvements can vary from person to person. Many patients report symptom relief within a few days to weeks, but it may take longer for others. It is essential to follow your doctor's recommendations regarding the duration of treatment, as they will monitor your progress and adjust the treatment plan as necessary.

As for the side effects, including decreased libido and the sensation of not fully ejaculating, these are not uncommon with medications that affect the prostate and urinary tract. If you find these side effects bothersome, it is important to communicate this with your healthcare provider. They may consider adjusting your dosage or switching you to a different medication that may have a more favorable side effect profile for you.

In terms of managing your sexual health while on this medication, it is advisable to maintain open communication with your doctor. If you feel that your libido is significantly affected or if the sensation of reverse ejaculation is distressing, your doctor may suggest alternative treatments. There are other classes of medications, such as 5-alpha-reductase inhibitors (like Finasteride), which can also help reduce prostate size and improve symptoms but may have different side effects.

Lastly, regarding your question about the frequency of masturbation while on this medication, it is generally a personal choice. However, if you find that it exacerbates your feelings of frustration or discomfort, you might consider reducing the frequency until you have a clearer understanding of how the medication affects you.
In summary, while reverse ejaculation can be an unsettling side effect of medications used for prostate health, it is typically not harmful. It is crucial to maintain an open dialogue with your healthcare provider about your symptoms and any concerns you have regarding your treatment. They can help you navigate these side effects and ensure that you receive the most effective and comfortable care possible.

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