Managing Hair Loss: Concerns About Finasteride and Mental Health - Dermatology

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Hair loss


A few years ago, I took Finasteride to suppress hair loss, but I had anxiety and depression prior to starting the medication.
After taking it for a significant period, my depression worsened considerably, and I am unsure if it was caused by the medication.
I went to a urologist and found out that my testosterone levels were very low.
The urologist believed this was related to taking Finasteride, but when I consulted a dermatologist, they advised me to continue taking it, stating that it would not harm my body.
It seems that I can take 5 mg of Finasteride once a week and apply Minoxidil 5% solution twice a day.
I have noticed that my hair loss appears to be quite severe.
Do you think this approach is reasonable? Since my treatment for mental health issues, depression, and low testosterone has been resolved, I have also heard from a doctor that taking Finasteride could contaminate semen and lead to birth defects.
Is this true? I am considering taking 5 mg of Finasteride once a week and applying Minoxidil 5% solution twice a day to see if it helps.
Do you think this is feasible? Thank you.

Niming, 30~39 year old female. Ask Date: 2022/10/21

Dr. Wu Yuxin reply Dermatology


I believe it is not feasible; from the perspective of treatment efficacy, it is still advisable to take 1 milligram daily.

Reply Date: 2022/10/21

More Info


Managing hair loss, particularly in the context of male pattern baldness (androgenetic alopecia), can be a multifaceted issue that involves understanding the underlying causes, treatment options, and potential side effects of medications like Finasteride (commonly known as Propecia) and Minoxidil. Your concerns about the relationship between these medications and mental health, particularly anxiety and depression, are valid and deserve careful consideration.


Understanding Finasteride and Its Effects
Finasteride is a 5-alpha-reductase inhibitor that works by blocking the conversion of testosterone to dihydrotestosterone (DHT), a hormone that contributes to hair loss in genetically predisposed individuals. While many users report positive results in terms of hair regrowth and stabilization of hair loss, some individuals experience side effects, including sexual dysfunction, mood changes, and depression.
Your experience of heightened anxiety and depression during the period of taking Finasteride raises an important point. Although the relationship between Finasteride and mood disorders is still being studied, some users have reported worsening mental health symptoms while on the medication. It is crucial to communicate openly with your healthcare provider about any mental health concerns, as they can help assess whether the medication may be contributing to your symptoms.


Testosterone Levels and Mental Health
You mentioned that your testosterone levels were found to be low during a urology consultation. Low testosterone can indeed contribute to mood disorders, fatigue, and decreased libido. It’s important to consider that while Finasteride can lower DHT levels, it may also have an impact on testosterone levels, although this varies among individuals. If your mental health issues have improved after addressing the low testosterone, it may be worth discussing with your healthcare provider whether continuing Finasteride is appropriate for you.


The Use of Minoxidil
Minoxidil is a topical treatment that promotes hair growth by increasing blood flow to hair follicles. It is often used in conjunction with Finasteride for a more comprehensive approach to treating hair loss. The combination of both treatments can be effective, but it’s essential to monitor how your body responds, especially considering your previous mental health challenges.


Concerns About Birth Defects
Regarding the concern about Finasteride contaminating semen and potentially leading to birth defects, it is true that Finasteride can be present in semen. However, the risk of causing birth defects is primarily a concern for women who are pregnant or may become pregnant. Men taking Finasteride should be cautious and inform their partners of their use of the medication, especially if there is a possibility of conception.


Suggested Approach
Given your situation, here are some recommendations:
1. Consult Your Healthcare Provider: Before making any changes to your medication regimen, it’s crucial to discuss your concerns with your healthcare provider. They can help you weigh the benefits and risks of continuing Finasteride and using Minoxidil.

2. Monitor Mental Health: If you decide to continue with Finasteride and Minoxidil, keep a close eye on your mental health. If you notice any worsening of symptoms, reach out to your healthcare provider immediately.

3. Consider a Holistic Approach: Addressing hair loss can also involve lifestyle changes, such as stress management techniques, a balanced diet, and regular exercise, which can positively impact both hair health and mental well-being.

4. Regular Follow-ups: Schedule regular follow-ups with both your dermatologist and mental health professional to ensure that all aspects of your health are being monitored and managed effectively.

In conclusion, while Finasteride and Minoxidil can be effective treatments for hair loss, it’s essential to approach their use thoughtfully, especially in the context of mental health. Open communication with your healthcare providers will be key to finding a treatment plan that works for you without compromising your overall well-being.

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