Is there a conflict between avocados and antiplatelet medications?
Hello, Doctor.
I am a patient who has undergone two stent placements and had a heart attack two years ago.
I am currently taking antiplatelet medication (Clopidogrel) and lipid-lowering medication (Rosuvastatin 10 mg and Ezetimibe 10 mg), and my LDL levels are maintained between 70-90.
I would like to inquire about the following foods:
1.
Avocado: I found online that it has good lipid-lowering effects.
However, it also mentioned that avocado may interact with anticoagulant medications.
Is this true? I was considering trying it to see if it could further lower my LDL.
The information I found states that avocado contains vitamin K, and for patients taking the anticoagulant Warfarin (a vitamin K antagonist), it is advisable to consume it in moderation and avoid continuous intake.
There were two cases where patients who had been on Warfarin for 6 weeks and 2 months, respectively, had their conditions stabilized but experienced a decrease in their International Normalized Ratio (INR) after consuming at least 100 grams of avocado daily for two days.
Although their INR returned to therapeutic levels after stopping avocado, it did reduce the medication's effectiveness, raising concerns about coagulation.
2.
Skim milk powder: Can I drink this? I am worried that it might raise my cholesterol levels.
Does skim milk not increase my LDL?
I have two questions, and I would greatly appreciate your clarification.
Thank you very much.
Xiao En, 40~49 year old female. Ask Date: 2022/10/28
Dr. Xie Peiru reply Nutrition
Hello:
1.
If LDL has already been reduced to standard levels, a low-fat diet is recommended; skim milk powder is acceptable to consume.
2.
According to the food composition analysis table, the vitamin K content in avocados is 0 µg; I am unsure if your source of information is accurate.
Here is a link for you to check the vitamin K content in avocados: https://consumer.fda.gov.tw/Food/tfndDetail.aspx?nodeID=178&f=0&id=371.
3.
It is advised that all foods should be consumed in moderation, and one should not consume large amounts solely for specific health benefits.
Wishing you good health~~ Nutrition Department, Chi Medical.
Reply Date: 2022/10/28
More Info
When it comes to dietary considerations for patients on antiplatelet medications, particularly those who have had a history of cardiovascular events such as heart attacks, it is essential to understand how certain foods can interact with medications and affect overall health.
Avocados and Antiplatelet Medications
Avocados are indeed known for their health benefits, particularly their ability to help lower LDL cholesterol levels due to their high content of monounsaturated fats and fiber. However, there is some concern regarding their interaction with anticoagulant medications, particularly warfarin, which is a vitamin K antagonist.
While avocados contain vitamin K, which can potentially affect the efficacy of warfarin, the interaction is not as pronounced with antiplatelet medications like clopidogrel (Plavix) or aspirin. The primary concern with vitamin K-rich foods is their effect on INR (International Normalized Ratio) levels in patients taking warfarin. In the case of antiplatelet medications, avocados do not have a significant impact on platelet function or the effectiveness of these drugs. Therefore, moderate consumption of avocados is generally considered safe for patients on antiplatelet therapy.
However, it is always wise to maintain a balanced diet and consume avocados in moderation. If you are considering increasing your avocado intake significantly, it would be prudent to discuss this with your healthcare provider to ensure it aligns with your overall dietary plan and health goals.
Skim Milk Powder and Cholesterol Levels
Regarding skim milk powder, it is a low-fat dairy option that can be beneficial for those concerned about cholesterol levels. Skim milk powder contains less saturated fat compared to whole milk products, which can help in managing LDL cholesterol levels. Consuming low-fat dairy products is generally recommended for individuals trying to maintain or lower their cholesterol levels.
Incorporating skim milk powder into your diet can provide essential nutrients such as calcium and protein without significantly raising your LDL cholesterol. However, it's important to consider the overall context of your diet. If you are consuming a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, incorporating skim milk powder should not adversely affect your cholesterol levels.
Conclusion
In summary, moderate consumption of avocados is generally safe for patients on antiplatelet medications, and they can be a beneficial addition to your diet due to their cholesterol-lowering properties. Skim milk powder is also a suitable option for those looking to manage their cholesterol levels effectively. Always consult with your healthcare provider or a registered dietitian before making significant changes to your diet, especially when managing chronic conditions and medications. They can provide personalized advice based on your specific health needs and medication regimen.
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