Hemoptysis in Lung Adenocarcinoma Patients Post-Surgery - Pulmonology

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Pulmonary adenocarcinoma with hemoptysis?


Hello, I am diagnosed with stage 3B lung adenocarcinoma and currently undergoing treatment with Alectinib.
I had surgery on November 3rd, and it has been almost two months since the operation.
Recently, I have noticed a small amount of blood in my cough when I wake up in the morning.
I just had a CT scan on December 1st, which showed no signs of deterioration.
Is this a concern? Is this normal? What could be the reason for this? Is it related to the surgery, the cold weather, disease progression, or a reaction to the medication? Thank you for your response, doctor.

Xiao Ke, 40~49 year old female. Ask Date: 2022/12/25

Dr. Zhou Ziguang reply Pulmonology


Hello: If there are no signs of deterioration on the CT scan, it is still possible that the microvascular structures near the trachea may be more prone to bleeding.
Please discuss this with your physician and seek medical attention for evaluation and treatment.

Reply Date: 2022/12/25

More Info


Hemoptysis, or coughing up blood, can be a concerning symptom for patients with lung adenocarcinoma, especially following surgery. In your case, as a patient who underwent surgery for stage 3B lung adenocarcinoma and is currently on treatment with Anlotinib, the presence of blood-streaked sputum can arise from several factors, and it is essential to consider the context of your recent surgery and overall health status.

Firstly, it is not uncommon for patients to experience some degree of hemoptysis after lung surgery. Surgical procedures can lead to irritation or inflammation of the airways and lung tissue, which may result in minor bleeding. This could be due to residual effects from the surgical site, especially if there was significant manipulation of the lung or surrounding structures during the operation. The healing process can sometimes lead to small blood vessels becoming fragile, resulting in minor bleeding, particularly when coughing.

Additionally, environmental factors such as cold weather can exacerbate respiratory symptoms. Cold air can lead to bronchial irritation, which might trigger coughing and potentially cause minor bleeding if the airways are inflamed or sensitive. If you have a history of chronic cough or bronchitis, this could also contribute to the presence of blood in your sputum.

It is also important to consider the possibility of disease progression or complications related to your lung cancer. While your recent CT scan indicated no worsening of your condition, it is crucial to remain vigilant. Hemoptysis can sometimes be a sign of tumor growth or metastasis, especially if it becomes more pronounced or is accompanied by other symptoms such as increased shortness of breath, chest pain, or significant changes in your overall health.

Moreover, the medication you are taking, Anlotinib, is a targeted therapy that can have side effects, including hypertension and potential effects on the respiratory system. While hemoptysis is not a commonly reported side effect, any new or unusual symptoms should be discussed with your healthcare provider.

In summary, while minor hemoptysis can occur post-surgery and may not always indicate a serious problem, it is essential to monitor the situation closely. If the blood-streaked sputum persists, increases in volume, or is accompanied by other concerning symptoms, you should contact your healthcare provider promptly. They may recommend further evaluation, such as repeat imaging or bronchoscopy, to rule out any complications or changes in your condition.

In conclusion, while your recent CT scan shows no signs of deterioration, the presence of blood in your sputum warrants attention. It is advisable to keep a record of your symptoms and discuss them with your oncologist during your next appointment. They can provide personalized advice based on your medical history and current treatment plan. Remember, open communication with your healthcare team is vital in managing your health and addressing any concerns you may have.

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