Depression, insomnia, etc?
Dear Dr.
Wu,
My mother has been diagnosed with anxiety and depression, and her current medications are as follows:
1.
Mirtazapine 3 mg: three times a day after meals
2.
Doxepin capsules 30 mg: two capsules at bedtime
3.
Lurasidone 10 mg: 0.5 capsule in the morning
4.
Escitalopram: one tablet at bedtime
She has been taking Mirtazapine and Doxepin for about 30 years, while Lurasidone and Escitalopram have been taken for approximately 3 weeks.
I would like to ask the following:
1.
Despite taking two Doxepin capsules and one Escitalopram tablet, she is still experiencing severe insomnia.
Recently, she has found that taking four Doxepin capsules and one Escitalopram tablet results in good sleep quality.
This combination is a short-term measure, and we plan to gradually reduce the Doxepin dosage once her sleep quality stabilizes.
Can the hospital provide a dosage of four Doxepin capsules daily as a short-term measure? If not, can we purchase it out-of-pocket? Alternatively, do you have other recommendations for managing insomnia?
2.
Can Mirtazapine and Lurasidone be taken together after breakfast?
3.
My mother continues to report a sore throat, but an ENT examination revealed no significant issues.
She has been on medication for nearly two weeks.
Is it possible that her sore throat (pharyngitis) is related to her depression? Are there any ways to alleviate this?
4.
Recently, my mother has also been experiencing frequent urination, but the volume each time is small.
Is it possible that this frequent urination is related to her depression? Are there any ways to improve this condition?
Thank you for your detailed attention and response, Dr.
Wu.
Afa, 50~59 year old female. Ask Date: 2023/02/17
Dr. Wu Enliang reply Psychiatry
1.
A user reports that taking 2 capsules of Danzhimen and 1 tablet of Eszopiclone still results in severe insomnia.
Recently, they found that taking 4 capsules of Danzhimen and 1 tablet of Eszopiclone achieves good sleep quality.
This combination is considered a short-term measure, and they plan to gradually reduce the dosage of Danzhimen once sleep quality stabilizes.
They inquire if the hospital can provide a dosage of 4 capsules of Danzhimen daily as a short-term solution.
If not, can they purchase it out-of-pocket? Or does the doctor have other recommendations for overcoming insomnia? The hospital cannot provide such a high dosage of sedative medication based on patient safety principles, nor can it be purchased out-of-pocket.
Recommendations for overcoming insomnia should address the underlying causes rather than continually increasing sedative medication.
2.
Can Mu Jing tablets and Liyou coated tablets be taken together after breakfast? Yes, they can.
3.
My mother has been continuously experiencing a sore throat, but the ENT examination showed no significant issues.
She has been on medication for nearly two weeks.
Is it possible that the sore throat is caused by depression (psychogenic pain)? What are the ways to improve this? If the ENT examination at a major hospital shows no problems, it is indeed possible that the symptoms are somatic manifestations of anxiety or depression.
The approach to improvement should focus on treating the depression and anxiety.
4.
My mother has also been experiencing frequent urination, but the volume each time is not significant.
Is it possible that this frequent urination is caused by depression? What are the ways to improve this? It is also possible.
The approach to improvement should similarly focus on treating the depression and anxiety.
Dr.
Wu Enliang.
Reply Date: 2023/02/17
More Info
Managing anxiety and depression, especially when it involves medication and sleep issues, can be quite complex. Your mother’s situation, as you described, involves a combination of long-term medication use and ongoing symptoms that are affecting her quality of life. Here’s a detailed response to your questions, along with some insights into managing these conditions.
1. Medication Adjustments for Sleep Issues
Your mother has been prescribed multiple medications, including 當眠多膠囊 (Duanmian Duo) and 艾斯樂錠 (Aisle), to help with sleep. It’s understandable that after 30 years of taking 牟靜錠 (Mujing) and 當眠多膠囊, she might still struggle with severe insomnia. Increasing the dosage of 當眠多膠囊 to four capsules may provide temporary relief, but it’s crucial to consult her prescribing physician before making any changes to her medication regimen.
In general, while some medications can be adjusted for short-term relief, they should be done under medical supervision to avoid potential side effects or dependency. If the hospital does not provide a higher dosage, purchasing the medication out-of-pocket may be an option, but again, this should be discussed with her healthcare provider.
Additionally, exploring non-pharmacological approaches to improve sleep quality, such as cognitive behavioral therapy for insomnia (CBT-I), relaxation techniques, and sleep hygiene practices, could be beneficial. These methods can help address the underlying issues contributing to her insomnia without solely relying on medication.
2. Combining Medications
Regarding the combination of 牟靜錠 and 離優膜衣錠 (Liyou) in the morning, it’s essential to follow the prescribing physician’s instructions. If both medications are intended to be taken at different times, combining them without consulting the doctor could lead to unintended interactions or side effects. Always check with her healthcare provider before making any changes to her medication schedule.
3. Throat Pain and Depression
Your mother’s persistent throat pain, despite normal ENT evaluations, raises the possibility of a psychosomatic response, which can occur in individuals with anxiety or depression. This condition, sometimes referred to as 喉球症 (Globus sensation), can manifest as a feeling of a lump in the throat or discomfort without any physical cause.
To address this, it may be helpful for her to engage in stress-reduction techniques, such as mindfulness, meditation, or therapy, which can alleviate some of the psychological stress contributing to her symptoms. Additionally, ensuring she stays hydrated and avoiding irritants (like smoking or strong odors) may help reduce throat discomfort.
4. Frequent Urination and Depression
Frequent urination can be a challenging symptom to manage, especially when it’s not accompanied by significant output. While it’s less common for depression to directly cause frequent urination, anxiety can lead to increased awareness of bodily sensations, which might make her more sensitive to the urge to urinate.
Encouraging her to maintain a regular hydration schedule and to avoid caffeine and alcohol, which can irritate the bladder, may help. If the problem persists, it would be wise to consult a urologist to rule out any underlying medical conditions that could be contributing to her symptoms.
Conclusion
In summary, managing your mother’s anxiety and depression, particularly concerning her medication and sleep issues, requires a careful and collaborative approach with her healthcare providers. Adjustments to her medication should always be made under medical supervision, and exploring additional therapeutic options may provide her with the relief she needs. Encouraging her to engage in holistic practices, such as therapy and lifestyle modifications, can also significantly improve her overall well-being.
If her symptoms persist or worsen, it’s crucial to seek further evaluation from her healthcare team to ensure she receives comprehensive care tailored to her needs.
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