Medication issues in ankylosing spondylitis?
Hello Dr.
Tseng, I am a patient with ankylosing spondylitis.
For the past six months, I have been taking two Salazopyrin and one Voltaren daily for treatment.
My CRP levels have been between 0.2 and 0.6, and my pain occurs approximately every two months for about 5-6 days (both CRP and pain levels have improved significantly compared to before treatment).
I have noticed that during these 5-6 days of pain, it tends to be concentrated every two months.
Therefore, I would like to ask the doctor:
1) Can I switch to taking Voltaren only when I experience pain (while continuing Salazopyrin), or am I concerned that not taking Voltaren daily and only taking Salazopyrin might cause my previously well-controlled CRP levels to rise significantly?
2) Since I take Voltaren daily but only experience pain for an average of 5-6 days every two months, is it unnecessary to take Voltaren on the pain-free days? My understanding is that Voltaren is just a pain reliever, and it is not needed when there is no pain.
Is this perspective correct? Thank you, doctor.
Shao, 20~29 year old female. Ask Date: 2023/03/17
Dr. Zeng Guosen reply Internal Medicine
Whether or not to take medication depends on the condition of the disease, including an overall assessment of pain, inflammation, and spinal involvement.
This determination must be made by your treating physician who understands your situation; it cannot be decided solely based on a written description.
Reply Date: 2023/03/17
More Info
Managing medication for Ankylosing Spondylitis (AS) requires a careful balance between controlling symptoms and minimizing potential side effects from medications. Your current regimen of taking two Salazopyrin (撒樂) and one Voltaren (萬客適) daily seems to be effective, as indicated by your CRP levels and the frequency of pain episodes. Here are some key considerations regarding your questions:
1. Adjusting Voltaren Usage: It is understandable to consider adjusting your medication based on your pain episodes. Voltaren, a non-steroidal anti-inflammatory drug (NSAID), is typically used to manage pain and inflammation. If your pain episodes are infrequent and manageable, you might contemplate taking Voltaren only during those flare-ups. However, it is crucial to consult your healthcare provider before making any changes. Stopping Voltaren could lead to an increase in inflammation, which might not be immediately apparent in your CRP levels. The CRP test is a marker of inflammation, but it may not reflect acute changes in your condition. Therefore, maintaining a consistent anti-inflammatory regimen can help prevent flares and manage underlying inflammation effectively.
2. Necessity of Daily Voltaren: Your understanding that Voltaren is primarily a pain reliever is correct; it is not necessary to take it daily if you are not experiencing pain. However, in the context of AS, NSAIDs like Voltaren also play a role in controlling inflammation, which is a critical aspect of managing the disease. Continuous use of NSAIDs can help maintain a lower baseline level of inflammation, potentially preventing flares. If you are experiencing significant improvement with your current regimen, it may be worth discussing with your doctor the possibility of a more tailored approach, such as taking Voltaren only during flare-ups while continuing Salazopyrin daily.
3. Monitoring and Follow-Up: Regular follow-ups with your rheumatologist are essential, especially when considering changes to your medication regimen. They can provide guidance based on your specific health status, monitor your CRP levels, and assess any potential side effects from long-term NSAID use. Additionally, they can evaluate the effectiveness of Salazopyrin in controlling your disease activity and whether adjustments are needed.
4. Lifestyle and Non-Pharmacological Interventions: Alongside medication management, incorporating lifestyle changes can significantly impact your overall well-being. Regular exercise, physical therapy, and maintaining good posture can help manage symptoms and improve mobility. Engaging in low-impact activities such as swimming or cycling can also be beneficial. Furthermore, consider discussing complementary therapies, such as acupuncture or physical therapy, which may provide additional relief without the need for increased medication.
5. Potential Side Effects: Long-term use of NSAIDs can lead to gastrointestinal issues, kidney problems, and cardiovascular risks. Therefore, it is vital to weigh the benefits of pain control against these potential risks. If you decide to adjust your medication, be vigilant for any signs of adverse effects and communicate them to your healthcare provider promptly.
In summary, while it may be reasonable to consider taking Voltaren only during pain episodes, it is essential to consult your healthcare provider before making any changes. Continuous monitoring of your condition and open communication with your doctor will help ensure that your treatment plan remains effective and safe.
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