Assessing HIV and Syphilis Risk After Unprotected Oral Sex: Key Insights - Urology

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HIV RT-PCR / Fat-abs IgM/IgG screening


I would like to ask, as a male, I received oral sex without a condom on March 8, and there were no visible wounds on my genitals.
The oral health status of the partner is unknown.
What is the risk of contracting HIV or syphilis in this situation? I underwent HIV RT-PCR and Fat-abs IgM/IgG screening on March 16, and all results were negative.
Is there a possibility of a conversion to positive? How accurate are these two screening tests?

Jjjjj, 30~39 year old female. Ask Date: 2023/03/17

Dr. Du Shixi reply Urology


Hello: There is a window period; please retest according to the recommendations of the testing unit (as different methods may yield varying results).
Wishing you good health.

Reply Date: 2023/03/17

More Info


When it comes to assessing the risk of HIV and syphilis after engaging in unprotected oral sex, it is essential to understand the transmission dynamics of these infections and the implications of your specific situation.
Firstly, it is important to note that oral sex is generally considered to be a lower-risk activity for HIV transmission compared to anal or vaginal intercourse. However, it is not without risk. The likelihood of contracting HIV through oral sex can be influenced by several factors, including the presence of cuts or sores in the mouth, the viral load of the HIV-positive partner, and the presence of other sexually transmitted infections (STIs). If the partner performing oral sex has bleeding gums, sores, or other oral health issues, the risk of transmission increases.

In your case, since you mentioned that there were no visible wounds on your genitalia and you engaged in unprotected oral sex, the risk of HIV transmission is relatively low but not zero. The fact that you underwent an HIV RT-PCR test on March 16, which returned negative, is a positive indicator. The RT-PCR test is highly sensitive and can detect the virus earlier than standard antibody tests, usually within 10 to 14 days after exposure. However, it is crucial to understand that there is still a window period during which the virus may not be detectable, especially if the exposure occurred shortly before the test.

Regarding syphilis, the risk of transmission through oral sex is also present, particularly if there are sores or lesions in the mouth or on the genitalia. Syphilis can be transmitted through direct contact with syphilitic sores, which may not always be visible. If the partner had syphilis, there is a risk of transmission, but again, the likelihood is lower than with anal or vaginal intercourse.

As for the accuracy of the tests you underwent, both the HIV RT-PCR and the antibody tests (Fat-abs IgM/IgG) are considered reliable. The RT-PCR test is particularly effective for early detection, while antibody tests are typically used for screening after the window period has passed. For HIV, it is generally recommended to retest at three months post-exposure to confirm a negative result, as some individuals may take longer to develop detectable antibodies.

In terms of your concerns about the possibility of a false negative result, it is essential to consider the timing of your tests. If you tested too soon after exposure, there is a chance that the virus was not yet detectable. If you continue to experience anxiety or fear regarding potential infection, it may be beneficial to consult with a healthcare provider for further testing and counseling.

To manage your anxiety during this waiting period, consider engaging in stress-reducing activities such as exercise, meditation, or talking to a mental health professional. It is also helpful to educate yourself about HIV and STIs from reputable sources, as knowledge can often alleviate fears.
In conclusion, while the risk of HIV and syphilis transmission through unprotected oral sex exists, the likelihood is generally lower than with other forms of sexual activity. Your negative test results are encouraging, but it is advisable to follow up with further testing at the appropriate intervals to ensure peace of mind. Always practice safer sex to reduce the risk of STIs in the future.

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