Should You Stop Oral Antibiotics for Acne? Expert Insights - Dermatology

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Oral antibiotics for acne?


Hello, doctor.
I started taking oral antibiotics (Doxycycline) on the night of April 16, and as of now, May 2, my acne has significantly decreased, with no large pimples remaining, just a few closed comedones.
I visited two clinics; one indicated that since there are no cystic acne lesions, I can stop the medication immediately, while the other advised that oral antibiotics can lead to antibiotic resistance and that I should continue taking them, but did not specify for how long.
Can I stop the medication? I am quite worried that continuing the treatment might lead to the development of folliculitis due to Malassezia.
I also have a history of easily developing flat warts and folliculitis on my face prior to my acne issues.

Bob Chen, 20~29 year old female. Ask Date: 2023/05/02

Dr. Wu Yuxin reply Dermatology


Whether or not to continue medication requires clinical judgment.
Without seeing the patient, I cannot provide you with advice.
It is recommended to discuss this with the original physician.

Reply Date: 2023/05/02

More Info


When considering whether to stop oral antibiotics for acne, particularly Doxycycline, it is essential to weigh the benefits against potential risks, including the development of antibiotic resistance and the recurrence of acne. Doxycycline is a tetracycline antibiotic commonly used to treat moderate to severe acne due to its anti-inflammatory properties and ability to reduce the bacteria that contribute to acne formation.

From your description, it appears that you have experienced a significant improvement in your acne condition since starting the Doxycycline treatment. The absence of large pimples and the reduction in overall acne severity are positive indicators that the antibiotic is working effectively. However, the decision to discontinue the medication should not be taken lightly and should ideally be guided by a healthcare professional.


Expert Insights on Stopping Doxycycline for Acne
1. Duration of Treatment: Typically, the duration of antibiotic therapy for acne can range from several weeks to several months, depending on the severity of the condition and the individual’s response to treatment. While some practitioners may suggest stopping the antibiotic once significant improvement is noted, others may recommend continuing treatment for a longer period to prevent relapse. Generally, a course of 3 to 6 months is common, but this can vary based on individual cases.

2. Risk of Antibiotic Resistance: One of the concerns with prolonged antibiotic use is the potential for developing antibiotic resistance. This can make future infections harder to treat. However, if you have already seen substantial improvement, your healthcare provider may assess whether the benefits of continuing the antibiotic outweigh the risks of resistance.

3. Consultation with Healthcare Providers: Since you have received differing opinions from two clinics, it would be prudent to consult with a dermatologist who specializes in acne treatment. They can provide a more tailored recommendation based on your specific skin condition, history of skin issues (like folliculitis and flat warts), and overall health.

4. Monitoring for Recurrence: If you decide to stop the antibiotic, it is crucial to monitor your skin closely for any signs of acne returning. If you notice a resurgence of acne, it may be necessary to reinitiate treatment or explore alternative therapies, such as topical retinoids or hormonal treatments, which can also be effective for acne management.

5. Alternative Treatments: If you are concerned about the potential for developing folliculitis or other skin issues, discussing alternative treatments with your dermatologist can be beneficial. Options may include topical treatments, lifestyle modifications, or even dietary changes that can support skin health without relying solely on antibiotics.

6. Skin Care Routine: Regardless of whether you continue or stop the antibiotic, maintaining a consistent and gentle skincare routine is vital. This includes using non-comedogenic products, avoiding harsh scrubs, and incorporating products that help manage oil production and inflammation.

In conclusion, while it is tempting to stop the antibiotic given your improvement, it is essential to consult with a healthcare professional to make an informed decision. They can provide guidance on the appropriate duration of treatment and help you manage any concerns about potential side effects or the risk of recurrence. Always prioritize a collaborative approach to your healthcare, especially when dealing with conditions like acne that can have both physical and emotional impacts.

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