Radiation Risks from Frequent CT Scans in Cancer Patients - Radiology

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Computed Tomography Radiation


Hello, I would like to ask two questions.

1.
A family member, aged 55, was diagnosed with renal cell carcinoma and is currently undergoing immunotherapy.
They need to have chest and abdominal CT scans every three months for monitoring, and they have already had six scans.
I would like to know at what cumulative radiation dose from these three-month follow-up scans would there be a concern for developing another cancer?
2.
Another family member, aged 54, is being monitored for a 0.5 cm pulmonary nodule at a regional hospital.
They had a low-dose CT scan of the lungs in March of last year, and this March, they had a standard-dose CT scan without contrast.
Subsequently, they sought a second opinion at a teaching hospital, where the physician advised that no immediate intervention was necessary and scheduled another standard-dose CT scan with contrast for the end of August.
Is the use of contrast necessary? Would a standard-dose CT scan be insufficient for accurate assessment? Thank you.

cc, 50~59 year old female. Ask Date: 2023/05/25

Dr. Wang Yifen reply Radiology


Hello, the necessity of X-ray radiation examinations is considered without limiting the radiation dose or the number of examinations.
The American Association of Physicists in Medicine issued a public statement in 2011 stating that if a single "radiation examination" has a radiation dose of less than 50 millisieverts, and multiple "radiation examinations" are performed within a short period (such as one year) with a total dose of less than 100 millisieverts, the potential risks associated with the "radiation dose" can be considered negligible, or even non-existent.
The use of contrast agents (dyes) during imaging examinations can enhance image clarity, and the decision to administer a contrast agent should be evaluated and arranged by the clinician based on the patient's condition.
Following the physician's instructions to undergo radiation-related examinations is important, as the health benefits outweigh the effects of radiation.
If there are any concerns, it is advisable to communicate with the physician before proceeding with the examination.
One should not avoid examinations out of fear of radiation, as this could lead to missed opportunities for disease treatment.
Please take this into consideration, and I wish you peace and health.

Reply Date: 2023/05/25

More Info


When considering the risks associated with frequent CT scans, particularly for cancer patients, it is essential to understand both the radiation exposure involved and the clinical necessity of these imaging studies.
1. Cumulative Radiation Exposure and Cancer Risk: For your family member who has undergone six CT scans in a year, it is crucial to evaluate the cumulative radiation dose. A standard chest CT typically delivers a dose of about 7-10 mSv, while an abdominal CT can range from 8-14 mSv. If we assume an average of 10 mSv per scan, six scans would result in approximately 60 mSv of radiation exposure over the year.
The risk of developing cancer from radiation exposure is often expressed in terms of increased lifetime cancer risk. For example, a dose of 10 mSv is estimated to increase the lifetime risk of cancer by about 0.05% (or 1 in 2,000). Therefore, with a cumulative dose of 60 mSv, the increased risk could be roughly 0.3% (or 3 in 1,000). While this increase is statistically significant, it is essential to weigh this risk against the benefits of monitoring for cancer recurrence, especially in a patient undergoing immunotherapy for renal cell carcinoma.
The decision to continue with regular imaging should be based on the clinical context, including the aggressiveness of the cancer, the patient's overall health, and the potential benefits of early detection of recurrence. It is advisable to discuss these concerns with the treating oncologist, who can provide insights into the necessity of ongoing imaging and whether alternative imaging modalities (like MRI or ultrasound) could be considered to reduce radiation exposure.

2. Use of Contrast Agents in Imaging: Regarding the second family member with a 0.5 cm pulmonary nodule, the use of contrast agents in CT scans is typically determined by the need for enhanced visualization of certain structures or abnormalities. In many cases, a non-contrast CT scan is sufficient to evaluate small nodules, especially if they have been stable over time.
The decision to use contrast should be based on the specific clinical scenario. If the physician believes that the additional detail provided by the contrast will significantly impact management decisions (for example, distinguishing between benign and malignant characteristics of the nodule), then it may be warranted. However, if the previous scans have shown stability and there are no concerning features, a non-contrast scan may suffice.

In summary, while the cumulative radiation exposure from frequent CT scans does carry some risk, the clinical benefits of monitoring cancer patients often outweigh these risks. It is crucial to maintain open communication with healthcare providers regarding the necessity of imaging studies and the potential use of contrast agents, ensuring that each decision is tailored to the patient's specific medical needs. Always consider discussing with the healthcare team about the frequency of scans and the possibility of alternative imaging methods that may pose less risk while still providing necessary diagnostic information.

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