Does Weight Loss Affect PLT and Hb Levels in Young Adults?

Q: Does Weight Loss Affect PLT and Hb Levels in Young Adults?

Hello Mr. <br>Hao： Weight loss can affect hemoglobin and platelet levels, but this varies from person to person. <br>A decrease in platelets may be caused by a reduction in adipose tissue and changes in certain internal factors. <br>A decrease in hemoglobin may result from nutrit

Does weight loss lead to a decrease in platelet count (PLT) and hemoglobin (Hb) levels?

Hello Dr.
Liu, I am 20 years old and 172 cm tall.
Six months ago, I weighed about 79 kg.
Over the past six months, I have worked hard to lose weight (mainly through exercise and diet, without medication, and maintaining normal lifestyle habits), and my weight has now dropped to 69 kg.
Six months ago, before I started losing weight, I had a blood test, and my platelet count (PLT) was 260, and my hemoglobin (Hb) was 13.8 (even earlier, during my school entrance examination, my PLT ranged between 250 and 300, and my Hb ranged between 13.5 and 14.5).
However, in my last two blood tests (two months apart), my PLT was 207 and 219, and my Hb was 12.6 and 13.2, which is a noticeable decrease compared to before.
I would like to ask the doctor, with a weight loss of 10 kg in six months: 1) Is it normal for PLT to decrease from 250-300 six months ago to 207-219 now during the weight loss process? 2) Is it normal for Hb to decrease from 13.5-14.5 six months ago to 12.6-13.2 now during the weight loss process? Thank you, doctor.

Hao, 20~29 year old female. Ask Date: 2023/06/28

Dr. Liu Hongxiang reply Family Medicine

Hello Mr.
Hao: Weight loss can affect hemoglobin and platelet levels, but this varies from person to person.
A decrease in platelets may be caused by a reduction in adipose tissue and changes in certain internal factors.
A decrease in hemoglobin may result from nutritional deficiencies during the weight loss process, particularly due to a reduction in iron levels.
These changes are common during weight loss, and it is recommended to consult healthcare professionals for a more accurate assessment and to ensure that physical fitness and health are maintained throughout the weight loss journey.
Wishing you mental and physical well-being.

Dr.
Liu Hongxiang

Reply Date: 2023/06/28

More Info

Weight loss can indeed have an impact on various blood parameters, including platelet count (PLT) and hemoglobin (Hb) levels, especially in young adults. In your case, you've experienced a significant weight loss of 10 kg over six months through exercise and dietary changes, which is commendable. However, the changes in your blood test results raise some important considerations.

1. Platelet Count (PLT): Your initial PLT was within the normal range (250-300), but it has decreased to 207 and 219 in recent tests. A drop in platelet count can occur for several reasons, including nutritional deficiencies, changes in hydration status, or even stress on the body due to weight loss. While a slight decrease in PLT can be normal, especially with significant weight loss, it is essential to ensure that you are not experiencing any underlying health issues. Factors such as dehydration can lead to a relative decrease in PLT, as the concentration of platelets may appear lower when blood volume is reduced. Additionally, if your diet during weight loss has been lacking in essential nutrients (like vitamins B12, folate, or iron), this could also contribute to changes in blood parameters.

2. Hemoglobin (Hb): Your Hb levels have also shown a decrease from 13.5-14.5 to 12.6-13.2. Hemoglobin levels can be influenced by several factors, including dietary intake, hydration status, and overall health. A decrease in Hb can indicate a reduction in red blood cell production or an increase in red blood cell destruction. In the context of weight loss, if your caloric intake has been significantly reduced or if you are not consuming enough iron-rich foods, this could lead to lower hemoglobin levels. It's crucial to ensure that your diet is balanced and includes adequate iron, vitamin B12, and folate, which are essential for red blood cell production.

In summary, while some fluctuations in PLT and Hb can occur during weight loss, significant or persistent changes warrant further investigation. It would be advisable to consult with your healthcare provider to discuss your blood test results in detail. They may recommend additional tests to rule out any underlying conditions, such as nutritional deficiencies or other hematological issues.
Moreover, maintaining a balanced diet that supports your weight loss goals while ensuring adequate nutrient intake is vital. Consider incorporating foods rich in iron (like lean meats, beans, and leafy greens), vitamin B12 (such as dairy products and fortified cereals), and folate (found in fruits, vegetables, and whole grains) into your meals. Staying hydrated is also essential, as dehydration can affect blood parameters.

In conclusion, while some changes in PLT and Hb can be expected during weight loss, monitoring these levels and ensuring a well-rounded diet is crucial for your overall health. Regular follow-ups with your healthcare provider will help you stay on track and address any concerns that may arise during your weight loss journey.

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