Effective Acne Treatment: A Guide to Using AHA and Retinoids - Dermatology

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Acne treatment


Hello, Doctor:
Q1: Would you recommend alternating the application of tretinoin (A acid) and mandelic acid for treatment?
Q2: Following up on the previous question, if it is recommended, what should be the order of application?
Q3: I have redness and dark spots (black and brown) on my face that I would like to lighten.
Are there any related medications available at regular pharmacies for treatment? If possible, I would like to know the names of the medications and how to apply them.
Thank you, Doctor!

cc, 10~19 year old female. Ask Date: 2023/06/30

Dr. Wu Yuxin reply Dermatology


It is not recommended to use them on the same day.
The method of use should be discussed with the physician who prescribed them to you.
Without examining the actual skin lesions, an online consultation cannot provide a prescription recommendation.

Reply Date: 2023/06/30

More Info


When it comes to effective acne treatment, particularly using Alpha Hydroxy Acids (AHAs) like mandelic acid and retinoids such as tretinoin (commonly referred to as "A酸" in Mandarin), there are several important considerations to keep in mind.
Q1: Should I alternate between retinoids and mandelic acid for treatment?
Yes, alternating between retinoids and AHAs can be an effective strategy for treating acne. Retinoids work by promoting cell turnover, preventing clogged pores, and reducing inflammation, while AHAs like mandelic acid help exfoliate the skin's surface, improving texture and tone. However, both can be irritating, especially when used together. Therefore, it is often recommended to use them on alternate days or to start with one product and gradually introduce the other to minimize irritation.

Q2: What should be the application order?
When using both products, a common approach is to apply them at different times of the day. For example, you might use mandelic acid in the morning and retinoids at night. If you choose to apply them on the same day, apply the AHA first, allow it to absorb for about 20-30 minutes, and then apply the retinoid. Always follow up with a good moisturizer to help mitigate dryness and irritation.

Q3: Are there over-the-counter products available for fading red and dark spots (hyperpigmentation) from acne?
Yes, there are several over-the-counter products that can help with hyperpigmentation. Look for products containing ingredients such as:
1. Hydroquinone: A skin-lightening agent that can help reduce dark spots.

2. Vitamin C (Ascorbic Acid): An antioxidant that can brighten the skin and reduce the appearance of dark spots.

3. Niacinamide: Known for its anti-inflammatory properties, it can help reduce redness and improve skin tone.

4. Azelaic Acid: This ingredient has both anti-inflammatory and skin-lightening properties, making it effective for treating acne and hyperpigmentation.

5. Kojic Acid: Another skin-lightening agent that can help reduce the appearance of dark spots.

When applying these products, it is generally recommended to cleanse your face first, then apply the treatment, and follow with a moisturizer. If you are using multiple products, start with the thinnest consistency and work your way to the thickest.

Additional Considerations:
- Sun Protection: It’s crucial to use sunscreen daily when using AHAs and retinoids, as they can increase your skin's sensitivity to the sun. A broad-spectrum sunscreen with an SPF of 30 or higher is recommended.


- Consultation with a Dermatologist: Since you have specific concerns about redness and dark spots, it may be beneficial to consult with a dermatologist. They can provide personalized recommendations based on your skin type and condition.

- Patience and Consistency: Acne treatment and fading hyperpigmentation can take time. It’s important to be patient and consistent with your skincare routine, as results may not be immediate.

In summary, alternating between retinoids and AHAs can be an effective strategy for treating acne and improving skin texture. There are also various over-the-counter options available for addressing hyperpigmentation. Always remember to protect your skin from the sun and consult with a dermatologist for tailored advice.

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