Prolonged Menstrual Bleeding After PCOS Diagnosis and Treatment - Obstetrics and Gynecology

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After being diagnosed with polycystic ovary syndrome (PCOS), I took medication to induce menstruation, but my period keeps coming?


Hello, doctor.
I have been diagnosed with polycystic ovary syndrome (PCOS) after having blood tests at a major hospital.
I have been taking Estrofem and Medroxyprogesterone for ten days to induce menstruation.
My period started on July 5 and has continued until now.
Initially, the bleeding was normal, but in the last few days, it has been light, with occasional drops or a sudden small flow.
When I wipe, I notice a slight red color (but no clots, just light bleeding).
The doctor at the hospital advised me to start taking Diane-35 to regulate my cycle from the second day of my period, and I am still taking it.
I would like to know: 1.
Is this prolonged menstruation related to PCOS and the use of medication to induce menstruation and contraceptives? 2.
I was planning to return for a follow-up appointment next weekend, but this ongoing menstruation has me quite worried.
Could it be indicative of other issues? (I found many concerns online regarding endometriosis and endometrial cancer.) 3.
Previously, I had an ultrasound and blood tests at the hospital, which confirmed PCOS, a thickened endometrium, and elevated male hormones, but I did not receive information about other potential conditions.
Should I consider switching hospitals or pursuing further examinations?

Xu, 20~29 year old female. Ask Date: 2023/07/23

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, having bleeding for this long is somewhat abnormal.
Please return to the original hospital and inform the doctor about this situation to see if additional medication is necessary.
Wishing you good health.

Reply Date: 2023/07/23

More Info


Prolonged menstrual bleeding after a diagnosis of polycystic ovary syndrome (PCOS) can be concerning, especially when combined with the use of hormonal treatments. Let's break down your situation and address your questions.

1. Connection Between Prolonged Bleeding, PCOS, and Hormonal Medications:
PCOS is a common endocrine disorder that can lead to irregular menstrual cycles and abnormal bleeding patterns. The hormonal imbalance associated with PCOS often results in a thickened endometrial lining, which can cause prolonged or heavy menstrual bleeding. The medications you mentioned, such as the hormonal treatments (like "益斯得" and "美得能"), are often prescribed to help regulate your menstrual cycle. However, these medications can also cause side effects, including breakthrough bleeding or prolonged periods, especially during the initial adjustment phase. It is not uncommon for women with PCOS to experience irregular bleeding when starting or adjusting hormonal treatments.

2. Concerns About Other Conditions:
Your concern about conditions such as endometriosis or endometrial cancer is understandable, especially given the prolonged nature of your bleeding. While these conditions can cause abnormal bleeding, they are not the most common outcomes for someone with PCOS. However, it is essential to monitor your symptoms closely. If the bleeding continues or worsens, or if you experience severe pain, it would be prudent to consult your healthcare provider sooner than your scheduled appointment. They may recommend further evaluation, such as a pelvic ultrasound or endometrial biopsy, to rule out other conditions.

3. Need for Further Evaluation or Change of Provider:
If you feel that your concerns are not being adequately addressed or if you are experiencing significant distress due to your symptoms, seeking a second opinion can be beneficial. It is essential to have a healthcare provider who listens to your concerns and provides thorough evaluations. Given your history of PCOS, thickened endometrial lining, and elevated androgen levels, it may be worthwhile to discuss the possibility of further investigations to rule out any other underlying issues. This could include additional imaging studies or blood tests to assess hormone levels and endometrial health.

In summary, while prolonged menstrual bleeding can be a side effect of hormonal treatments and is often related to PCOS, it is crucial to remain vigilant about your symptoms. Regular follow-ups with your healthcare provider are essential, and do not hesitate to seek further evaluation if your symptoms persist or worsen. Maintaining open communication with your doctor about your concerns will help ensure that you receive the appropriate care and management for your condition.

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