Interpreting Myocardial Perfusion Reports: Insights on Ischemic Heart Disease - Cardiology

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Interpretation of Myocardial Perfusion Report


Hello, Director Wu.
Could you please help interpret the following report? I'm unsure what the issues are.
Imaging findings: Dipyridamole Tl-201 myocardial perfusion gated SPECT: 1.
Persantin (dipyridamole) 0.56 mg/kg was administered by intravenous infusion for 4 minutes, following standard protocol.
During the stress test, blood pressure dropped from 130/77 to 112/70 mmHg and heart rate increased from 62 to 76 bpm.
The body weight is 73 kg.
The SPECT analysis was performed using the Astonish and FBP algorithm (Philips Bright View).
Findings include myocardial hypertrophy; inflated lungs with faint bilateral pulmonary radioactivity; dilated right ventricle with heterogeneous wall uptake; TID: 0.97; LHR: 0.31; functional kidneys; heterogeneously reduced thallium uptake in the thyroid; and heterogeneous perfusion with mild reductions in the apical, inferoapical, inferior, and proximal anteroseptal walls.
Estimated gated left ventricular ejection fraction (LVEF): 59%; septoapical dyskinesia.
Redistribution SPECT imaging revealed: heterogeneously mild reversible redistribution in the anteroseptal, septal, inferior, and lateroapical walls; suspected anteroapical injury.
3.
The above findings suggest: - a positive result for myocardial perfusion imaging (MPI) indicating chronic ischemic heart disease with heterogeneous mild reversibility in the anteroseptal, septal, inferior, and lateroapical walls; suspected apical injury.
Impression: 1.
The MPI is consistent with chronic ischemic heart disease, associated with heterogeneous mild reversibility, primarily in the anteroseptal, septal, inferior, and lateroapical walls; suspected occult coronary artery disease (CAD) involving the left anterior descending artery (LAD), please correlate with clinical findings.
2.
Well-preserved LVEF (59%) during the stress study; suspected right ventricular strain.
3.
Suspected chronic obstructive pulmonary disease (COPD).
Thank you!

Mr. Lin, 50~59 year old female. Ask Date: 2023/08/06

Dr. Wu Xueming reply Cardiology


The examination results indicate mild myocardial ischemia, which may suggest the presence of coronary artery stenosis.
Please consult with your physician in the outpatient clinic regarding further treatment options.

Reply Date: 2023/08/06

More Info


Interpreting myocardial perfusion reports is crucial for understanding the underlying cardiac conditions, particularly ischemic heart disease (IHD). The report you provided indicates several key findings that suggest the presence of chronic ischemic heart disease, as well as potential coronary artery disease (CAD). Let’s break down the findings and their implications.


Key Findings from the Report
1. Stress Testing and Hemodynamics: The patient underwent a dipyridamole stress test, which is a pharmacological method to induce stress on the heart when exercise is not feasible. The drop in blood pressure from 130/77 mmHg to 112/70 mmHg and an increase in heart rate from 62 to 76 bpm indicate that the heart was responding to the stressor, but the blood pressure drop could suggest some level of cardiac compromise.

2. SPECT Imaging Results: The SPECT (Single Photon Emission Computed Tomography) imaging revealed mild reductions in perfusion in several areas of the heart, particularly the apical, inferoapical, inferior, and proximal anteroseptal walls. This suggests that these regions may not be receiving adequate blood flow, which is characteristic of ischemia.

3. Left Ventricular Ejection Fraction (LVEF): The estimated LVEF of 59% during the stress test indicates that the heart's pumping ability is still within a reasonable range, although it is on the lower end of normal. A normal LVEF typically ranges from 55% to 70%. The presence of septoapical dyskinesia, which refers to abnormal movement in the septal region of the heart, is concerning as it may indicate underlying ischemia or previous myocardial damage.

4. Redistribution Imaging: The report mentions mild reversible redistribution in the anteroseptal, septal, inferior, and lateroapical walls. This suggests that there is some degree of ischemia that may improve with rest, which is a positive sign but still indicates underlying issues.

5. Impression of Chronic Ischemic Heart Disease: The report concludes that the findings are consistent with chronic ischemic heart disease, with a suspicion of occult CAD, particularly involving the left anterior descending artery (LAD). This is significant as the LAD supplies a large portion of the heart muscle, and blockages here can lead to serious cardiac events.


Clinical Implications
Given these findings, it is essential to correlate them with the patient's clinical history and symptoms. The presence of chronic ischemic heart disease suggests that the patient may be at risk for future cardiac events, such as myocardial infarction (heart attack). The report also raises the possibility of coronary artery disease, which may require further evaluation through coronary angiography to assess the severity and extent of any blockages.


Recommendations
1. Follow-Up with a Cardiologist: It is crucial for the patient to discuss these findings with a cardiologist. The physician may recommend further diagnostic tests, such as coronary angiography, to visualize the coronary arteries directly.

2. Management of Risk Factors: The patient should also be evaluated for modifiable risk factors such as hypertension, diabetes, and hyperlipidemia. Lifestyle modifications, including diet, exercise, and smoking cessation, should be emphasized.

3. Medical Management: Depending on the severity of the findings and the patient's overall risk profile, medical management may include antiplatelet therapy, statins, beta-blockers, or other medications aimed at improving heart function and reducing the risk of ischemic events.

4. Monitoring and Lifestyle Changes: Regular follow-up appointments should be scheduled to monitor the patient's condition, and lifestyle changes should be encouraged to improve overall cardiovascular health.

In conclusion, the report indicates significant findings that warrant further investigation and management. Understanding these results is vital for preventing potential complications associated with ischemic heart disease and ensuring optimal patient care.

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