Urine Ketones: What Does a 3+ Result Mean for Your Health? - Internal Medicine

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The medical examination report indicates urine ketones at 3+?


Hello doctor, in April of this year, I experienced redness, swelling, and pain in my left foot, and a doctor at a clinic diagnosed it as gout (without blood tests).
I have a history of gout and usually manage my diet, primarily following a low purine, low GI diet (mostly vegetables and eggs).
I do weight training once a week and have boxing cardio three days a week.
Today, I received part of my blood and urine test results (some results will come in a month).
Currently, I know my height is 165.2 cm, weight is 50 kg, abdominal fat is 0.7, uric acid is 5.9, fasting blood glucose is 84, pre-meal insulin is 3.7, insulin resistance is 0.8, hemoglobin A1c is unknown, urine glucose is negative, but urine ketones are 3+.
I researched online and found that this could be related to diabetes or prolonged fasting.
The day before my test, I did weight training and interval training for a total of two hours in the afternoon, had dinner around 7:00 PM, drank water for the last time at 9:00 PM, and did not eat breakfast until after 11:00 AM the next day (only vegetables, no carbohydrates).
I went for the urine test right after eating.
Could this be the reason for the urine ketones being 3+? I'm a bit worried it might indicate diabetes...

Casey, 20~29 year old female. Ask Date: 2023/10/30

Dr. Li Jian reply Internal Medicine


The production of urine ketones is usually related to prolonged fasting.
Please consult a metabolic specialist.
Thank you for your inquiry.

Reply Date: 2023/10/30

More Info


Understanding urine ketones, especially when you receive a result of 3+, can be quite concerning, particularly if you have a history of conditions like gout and are actively managing your diet and exercise. Let's break down what a 3+ ketone result means and how it relates to your overall health.


What Are Urine Ketones?
Ketones are byproducts produced when your body breaks down fat for energy instead of carbohydrates. This process typically occurs during periods of fasting, prolonged exercise, or when carbohydrate intake is significantly reduced, such as in low-carb diets. In a healthy individual, the body primarily uses glucose for energy. However, when glucose is scarce, the body turns to fat stores, leading to the production of ketones.


Interpreting a 3+ Ketone Result
A urine ketone level of 3+ indicates a significant presence of ketones in your urine. This level suggests that your body is in a state of ketosis, which can occur for several reasons:
1. Fasting or Prolonged Exercise: Given that you mentioned engaging in two hours of weight training and high-intensity interval training (HIIT) the day before your test, it’s possible that your body utilized fat stores for energy during this period, leading to elevated ketone levels.

2. Low Carbohydrate Intake: Your diet, which is low in carbohydrates and high in vegetables and proteins, can also contribute to ketosis. If your carbohydrate intake is consistently low, your body may adapt to using fat as its primary energy source.

3. Diabetes: While your blood glucose levels appear normal (with a fasting blood sugar of 84 mg/dL), a high level of ketones can be concerning for individuals with diabetes, particularly if they are unable to utilize glucose effectively due to insulin resistance or lack of insulin. However, your insulin resistance score of 0.8 suggests that you are not currently experiencing significant insulin resistance.


Potential Health Implications
- Diabetic Ketoacidosis (DKA): This is a serious condition that can occur in individuals with uncontrolled diabetes, where high levels of ketones lead to acidosis. However, given your normal blood glucose levels, this is less likely to be a concern for you at this time.

- Nutritional Ketosis: If you are intentionally following a low-carb diet, a 3+ ketone level may simply indicate that you are in a state of nutritional ketosis, which is often sought after in ketogenic diets for weight loss and improved metabolic health.


Recommendations
1. Monitor Your Symptoms: Pay attention to how you feel. If you experience symptoms such as excessive thirst, frequent urination, nausea, or abdominal pain, it would be wise to seek medical attention.

2. Hydration: Ensure you are adequately hydrated, especially if you are exercising intensely and following a low-carb diet, as dehydration can exacerbate the concentration of ketones in your urine.

3. Consult Your Healthcare Provider: Given your concerns about diabetes and the presence of ketones, it’s advisable to discuss these results with your healthcare provider. They may recommend further testing, such as blood ketone levels or additional metabolic panels, to clarify your health status.

4. Dietary Adjustments: If you are concerned about the ketone levels, consider adjusting your carbohydrate intake slightly to see if it affects your ketone levels while still maintaining a balanced diet.

In conclusion, while a 3+ ketone result can be alarming, it is essential to consider the context of your diet and exercise. It is likely that your recent activities and dietary choices have led to this result. However, ongoing monitoring and consultation with your healthcare provider will help ensure that you maintain optimal health and address any potential issues early on.

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