Kidney Function Decline in Healthy Aging Adults - Internal Medicine

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Kidney problems


Hello, doctor.
I have come to inquire about some related issues that my friends and family have been experiencing.
The patient is a 55-year-old female who maintains a healthy diet (primarily whole foods, with minimal intake of refined, high-sugar, and high-fat foods).
She does not exhibit symptoms of metabolic syndrome and has no proteinuria.
However, her health check report shows an eGFR value between 60 and 70.
I would like to know if this decline in values is due to aging, or if there are other underlying causes.
Additionally, should she start to reduce her phosphorus intake, such as from whole grains, or can she maintain her normal diet?

Ms. Huang, 20~29 year old female. Ask Date: 2023/12/14

Dr. Wu Hongjie reply Internal Medicine


eGFR 60-70, with no proteinuria, kidney function decline may be attributed to age factors.
A low-phosphorus diet currently benefits those in stage 3 (GFR < 60) and it remains inconclusive whether implementing it earlier has advantages.

Reply Date: 2023/12/14

More Info


Understanding kidney function decline in healthy aging adults is a multifaceted issue that involves various physiological changes, dietary habits, and individual health conditions. In the case of a 55-year-old woman with an estimated glomerular filtration rate (eGFR) between 60-70 mL/min/1.73m², it is essential to consider several factors that may contribute to this decline.

Firstly, it is important to recognize that kidney function naturally declines with age. This decline can be attributed to a combination of factors, including decreased renal blood flow, reduced nephron number, and changes in glomerular structure. As individuals age, the kidneys may become less efficient at filtering waste products from the blood, which can lead to a gradual decrease in eGFR. In many cases, a slight reduction in eGFR, particularly in the range of 60-70, may not indicate significant kidney dysfunction, especially if there are no accompanying symptoms or signs of kidney disease, such as proteinuria or hypertension.

In this specific scenario, the individual maintains a healthy diet, avoiding refined sugars and unhealthy fats, which is commendable. A diet rich in whole foods, fruits, vegetables, and lean proteins can support overall health and potentially mitigate some age-related declines in kidney function. However, it is crucial to monitor dietary phosphorus intake, particularly if eGFR falls below 60 mL/min, as excessive phosphorus can lead to complications such as cardiovascular disease and bone health issues.

Regarding the question of whether to reduce phosphorus intake, it is generally advisable to maintain a balanced diet that includes phosphorus-rich foods, such as whole grains, nuts, and dairy products, unless there is a specific indication to limit phosphorus due to declining kidney function. Since the eGFR is still within a relatively stable range, it may not be necessary to make drastic dietary changes at this time. Instead, focusing on overall dietary quality, hydration, and regular monitoring of kidney function through blood tests can be beneficial.

It is also essential to consider other potential factors that could contribute to a decline in kidney function, such as dehydration, medications, or underlying health conditions. Regular check-ups with a healthcare provider can help identify any changes in kidney function and allow for timely interventions if necessary.

In summary, while age-related decline in kidney function is common, maintaining a healthy lifestyle, including a balanced diet and regular physical activity, can help support kidney health. Monitoring eGFR and other kidney function markers is crucial, and any significant changes should prompt further evaluation by a healthcare professional. If there are concerns about phosphorus intake or other dietary factors, consulting with a registered dietitian or nephrologist can provide personalized guidance tailored to individual health needs.

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