Gum Hyperkeratosis: Risks and Preventive Measures - Dentistry

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Hello Dr.
Tseng: I apologize for bothering you again with my questions.
Regarding your response to the inquiry in "#204354", you mentioned: "Long-term friction from chewing food may increase the degree of keratinization, and there is a possibility of malignant transformation.
It is recommended to adjust the occlusion and have regular follow-up examinations." I would like to ask Dr.
Tseng: Q1.
Generally speaking (or in clinical practice), how high is the probability of malignant transformation occurring from keratinized semicircular scar protrusions on the gums due to friction from occlusion and chewing? Q2.
Given that there is a possibility of malignant transformation, should I consider "preventive excision" of the keratinized semicircular scar protrusions on my gums? Thank you, Dr.
Tseng.

Kris, 40~49 year old female. Ask Date: 2024/01/10

Dr. Zeng Guanghui reply Dentistry


Dear Mr.
Kris,
Thank you for reaching out again for consultation.
Since I have not had the opportunity to examine you in person, I still recommend discussing your concerns during your regular follow-up appointments with your physician.
This will allow for more appropriate management suggestions tailored to your current situation.

Sincerely,
Director Tseng Guang-Hui, Dental Department, Nantou Hospital

Reply Date: 2024/01/10

More Info


Gum hyperkeratosis, characterized by the thickening of the gum tissue due to excessive keratin production, can arise from various factors, including chronic irritation from biting, chewing, or poor dental hygiene. Understanding its risks and preventive measures is crucial for maintaining oral health.


Q1: Risk of Malignant Transformation
The risk of malignant transformation in gum hyperkeratosis is generally considered low, especially in cases where the hyperkeratosis is solely due to mechanical irritation, such as from teeth grinding or improper dental alignment. However, chronic irritation can lead to dysplastic changes in the epithelial cells, which may increase the risk of oral squamous cell carcinoma (OSCC) over time. The likelihood of such transformation varies based on individual factors, including genetic predisposition, overall health, and lifestyle choices (e.g., tobacco use, alcohol consumption).

In clinical practice, while the risk is not negligible, it is not common for benign hyperkeratosis to progress to malignancy. Regular dental check-ups are essential for monitoring any changes in the gum tissue. Dentists often recommend biopsies of suspicious lesions to rule out dysplasia or malignancy, especially if there are other risk factors present.


Q2: Preventive Measures and Surgical Intervention
Regarding the question of whether to perform "preventive excision" of the hyperkeratotic lesions, this decision should be made on a case-by-case basis. If the hyperkeratosis is symptomatic, causing discomfort, or if there are signs of dysplasia, surgical intervention may be warranted. However, if the lesions are asymptomatic and stable, regular monitoring may be sufficient.

Preventive measures for gum hyperkeratosis include:
1. Improving Oral Hygiene: Maintaining good oral hygiene can help reduce irritation and inflammation. Regular brushing and flossing can prevent plaque buildup, which may contribute to gum problems.

2. Regular Dental Visits: Routine dental check-ups allow for early detection of any changes in gum tissue. Dentists can provide professional cleanings and monitor for any signs of dysplasia or malignancy.

3. Addressing Mechanical Irritation: If the hyperkeratosis is due to mechanical factors, such as misaligned teeth or ill-fitting dentures, addressing these issues can help reduce irritation. Orthodontic treatment or adjustments to dental appliances may be necessary.

4. Lifestyle Modifications: Avoiding tobacco products and limiting alcohol consumption can significantly reduce the risk of oral cancers. A balanced diet rich in antioxidants may also support oral health.

5. Regular Monitoring: If hyperkeratosis is diagnosed, regular follow-ups with a dental professional are crucial. They can assess any changes in the lesion and recommend further action if necessary.

In conclusion, while the risk of malignant transformation from gum hyperkeratosis exists, it is relatively low in most cases. Preventive measures, including maintaining good oral hygiene, addressing mechanical irritants, and regular dental check-ups, are essential for managing gum health. If there are concerns about the nature of the hyperkeratosis, discussing the possibility of surgical intervention with a dental professional is advisable. Regular monitoring and a proactive approach to oral health can help mitigate risks and ensure early detection of any potential issues.

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