Frequent urination, bacterial culture?
Hello Doctor,
Recently, my mother has been experiencing severe frequent urination, going more than 15 times a day, with only small amounts each time.
She went to the hospital for a urinalysis and urine culture.
The urinalysis report on the same day indicated no infection.
However, a few days later, when I took her back for a follow-up, the doctor said that the urine culture showed an infection.
Could you please explain why the urinalysis showed no infection while the urine culture indicated a bacterial infection? What could be the reason for this discrepancy? Currently, the doctor has prescribed levofloxacin, one tablet every morning.
Thank you for your assistance.
Niming, 60~69 year old female. Ask Date: 2024/02/22
Dr. Du Shixi reply Urology
Hello: In addition to the presence of bacteria that may already exist in the urine, females may also contaminate the urine during collection due to the difficulty of urination.
However, for safety reasons, since urinary tract infections can also cause frequent urination, doctors often prescribe antibiotics for treatment.
Wishing you good health.
Reply Date: 2024/02/22
More Info
Frequent urination can be a perplexing symptom, especially when urine tests yield inconsistent results. In your mother's case, the discrepancy between the initial urine test showing no infection and the subsequent urine culture indicating a bacterial infection can be attributed to several factors.
Firstly, it's important to understand the difference between a standard urinalysis and a urine culture. A urinalysis is a quick test that examines the physical and chemical properties of urine, including the presence of red and white blood cells, protein, glucose, and nitrites, among other indicators. This test can provide immediate results and is often used as a preliminary screening tool. However, it may not always detect all infections, particularly if the bacteria present are in low numbers or if the infection is caused by organisms that do not produce nitrites.
On the other hand, a urine culture is a more specific test that involves growing bacteria from a urine sample in a laboratory setting. This process can take 24 to 48 hours and is designed to identify the exact type of bacteria causing the infection, as well as its sensitivity to various antibiotics. This is why a urine culture can sometimes reveal an infection that a standard urinalysis does not.
In your mother's case, the initial urinalysis may have missed the infection due to the low concentration of bacteria in the urine at the time of testing. Additionally, if she had recently urinated before the test, the sample might have been diluted, further reducing the likelihood of detecting an infection. The urine culture, however, would have provided a more accurate assessment of the urinary tract's status, leading to the diagnosis of a bacterial infection.
Frequent urination can also be caused by other factors, such as bladder irritation, overactive bladder syndrome, or even certain medications. In your mother's case, the prescribed antibiotic, levofloxacin, is commonly used to treat urinary tract infections (UTIs) and should help alleviate her symptoms. It's crucial to ensure that she completes the full course of antibiotics as prescribed, even if her symptoms improve before finishing the medication.
In summary, the inconsistency between the urinalysis and urine culture results can be explained by the limitations of the initial test and the more thorough nature of the culture. If your mother continues to experience symptoms or if new symptoms arise, it is essential to follow up with her healthcare provider for further evaluation and management. Additionally, keeping a record of her symptoms, fluid intake, and any changes in her urinary habits can provide valuable information for her healthcare team.
In conclusion, while frequent urination can be concerning, understanding the testing process and the nature of urinary tract infections can help clarify the situation. If you have any further questions or concerns, don't hesitate to reach out to her healthcare provider for more personalized guidance.
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