Do I Need to Retest After a Negative Saliva HIV Test? - Urology

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HIV saliva rapid test


Hello doctor, it has been five and a half months since my last high-risk behavior.
I used a saliva rapid test, and it came back negative.
I would like to ask if I still need to get retested.
If I do get retested and the saliva rapid test is negative again, can I feel assured?

Dong Dong, 20~29 year old female. Ask Date: 2024/04/18

Dr. Du Shixi reply Urology


Hello: To assess the quality of a rapid test, I generally recommend that if you are very concerned, you should consider a blood test.
Wishing you good health.

Reply Date: 2024/04/18

More Info


When it comes to HIV testing, understanding the implications of your results and the timing of your tests is crucial. Based on your situation, where you had a high-risk sexual encounter over five months ago and have since tested negative using a saliva rapid test, it is important to consider a few key factors.

Firstly, the window period for HIV tests varies depending on the type of test used. For most antibody tests, including saliva tests, the window period is typically around 3 months (or 90 days). This means that if you test negative after this period, the likelihood of being infected is significantly reduced. However, some tests, particularly those that detect both antibodies and antigens (like the fourth-generation tests), can provide reliable results as early as 2-4 weeks after exposure.

Since you mentioned that it has been five and a half months since your last high-risk encounter, and you received a negative result from a saliva test, you are likely in a very low-risk category for HIV infection. The Centers for Disease Control and Prevention (CDC) states that if you have a negative result after the window period, you can generally consider yourself not infected.

However, if you are still feeling anxious or uncertain about your status, it is perfectly reasonable to consider retesting. Many healthcare providers recommend a follow-up test for peace of mind, especially if you have ongoing concerns or symptoms that may be related to other health issues. If you choose to retest, using a different method, such as a blood test, may provide more comprehensive results. Blood tests are generally considered more accurate than saliva tests, particularly in detecting HIV.

In your case, if you decide to retest and receive another negative result, you can feel more confident about your HIV status. It is also important to remember that while a negative result is reassuring, it does not eliminate the need for safe practices in the future. Using condoms consistently and correctly, and considering pre-exposure prophylaxis (PrEP) if you are at ongoing risk, are effective ways to prevent HIV transmission.

Additionally, if you have any symptoms that are concerning you, such as persistent sore throat or other unusual signs, it would be wise to consult with a healthcare provider. They can evaluate your symptoms in the context of your overall health and may recommend additional testing for other sexually transmitted infections (STIs) or conditions.

In summary, while your negative saliva test after five and a half months is a strong indicator that you are not infected with HIV, retesting can provide additional reassurance. If you choose to retest, consider using a blood test for more definitive results. Always prioritize safe practices in your sexual health to minimize risks in the future. If you have any lingering concerns or symptoms, do not hesitate to seek medical advice.

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