Missed Period After RU486: What You Need to Know - Obstetrics and Gynecology

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When it comes to missed periods after taking RU486 (mifepristone), it's important to understand the medication's effects and the body's response to it. RU486 is commonly used in medical abortions, and it works by blocking the hormone progesterone, which is necessary for maintaining a pregnancy. After taking RU486, a second medication, usually a prostaglandin like misoprostol, is taken to induce contractions and expel the pregnancy tissue.

In your case, you took RU486 on August 19 and followed it with the prostaglandin on August 21. You mentioned that you took a pregnancy test on September 21, which returned a negative result. However, you are concerned about your missed menstrual period.

Firstly, it's important to note that after a medical abortion, it can take some time for your menstrual cycle to return to its normal rhythm. The timing can vary significantly from person to person. Some women may experience their next period within a few weeks, while others may take longer—up to several months—before their cycle normalizes. Factors such as hormonal fluctuations, stress, and individual health can all play a role in this variability.

Since you have taken RU486 and the prostaglandin, the absence of your period could be a normal part of the process. However, if you are still experiencing a missed period after a few weeks, it may be advisable to take another pregnancy test to rule out the possibility of an incomplete abortion or a new pregnancy. If the test is still negative and your period does not arrive, it would be wise to consult with a healthcare provider for further evaluation.

Additionally, if you experience any concerning symptoms such as severe abdominal pain, heavy bleeding, or signs of infection (such as fever or foul-smelling discharge), you should seek medical attention immediately. These could indicate complications that need to be addressed.

In summary, while it is not uncommon to miss a period after taking RU486, especially if the abortion was recent, it is essential to monitor your body’s response and consult with a healthcare professional if you have any concerns or if your period does not return in a reasonable timeframe. Your health and well-being are paramount, and a healthcare provider can offer personalized advice and support based on your specific situation.