Antibiotics: Classification, Usage, and Impact on Health - Family Medicine

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Consulting Family Medicine: Questions about Antibiotics?


(1) How many classes of antibiotics are there currently? Is this classification an internationally standardized system, or is it defined by the local health authority? Does a lower number indicate that the antibiotic is weaker? (Is the first-line antibiotic the weakest?)
(2) I have heard that to prevent antibiotic misuse, prescribing physicians should consult with infectious disease specialists.
What is the purpose of this consultation?
(3) Besides killing bacteria, what effects do antibiotics have on the human body (such as on human cells)?
(4) It is said that antibiotics are not necessary for viral infections, and should only be considered for bacterial infections.
Why is this? Is it because bacteria are stronger than viruses?
(5) [a] What are the different methods of administering antibiotics? (I mean, like oral and injectable forms, etc.) [b] If an antibiotic can be taken orally as well as injected, does this mean that the antibiotic is formulated in a certain way (like in liquid form) so that it can be used for both oral and injectable routes? Or is it that the same antibiotic is made into tablets or capsules for oral use, while a different liquid formulation is used for injection to meet different needs? Sincerely, Mr.
Li, a 30-year-old citizen.

Mr. Li, 30~39 year old female. Ask Date: 2004/09/29

Dr. Cai Jueren reply Family Medicine


Antibiotics should be used according to a physician's instructions and should not be self-administered.
If there are any issues, it is best to consult a doctor.

Reply Date: 2004/09/29

More Info


Antibiotics are a crucial part of modern medicine, used primarily to treat bacterial infections. Understanding their classification, usage, and effects on health is essential for both healthcare providers and patients. Here’s a comprehensive overview addressing your questions.

1. Classification of Antibiotics: Antibiotics are generally classified into "first-line," "second-line," and "third-line" categories based on their effectiveness, spectrum of activity, and the severity of infections they are used to treat. This classification is not universally standardized; it can vary by country and by the specific guidelines of health organizations. In many cases, first-line antibiotics are those that are most effective for common infections and have a lower risk of resistance. However, it is a misconception that first-line antibiotics are the weakest; rather, they are often the most appropriate and effective for specific conditions. The classification reflects their usage in clinical practice rather than their inherent strength.

2. Consultation with Infectious Disease Specialists: When prescribing antibiotics, especially for complicated infections or when resistance is a concern, physicians may consult with infectious disease specialists. This collaboration aims to ensure the most effective antibiotic is chosen, minimizing the risk of resistance and optimizing patient outcomes. Infectious disease specialists have extensive knowledge of the latest research, resistance patterns, and treatment protocols, which can be invaluable in managing complex cases.

3. Impact on Human Cells: While antibiotics are designed to target bacteria, they can also affect human cells. For instance, broad-spectrum antibiotics can disrupt the balance of normal flora in the gut, leading to side effects such as diarrhea or yeast infections. Additionally, some antibiotics can have toxic effects on organs, such as the liver and kidneys, especially with prolonged use or in patients with pre-existing conditions. It’s crucial for healthcare providers to monitor patients for potential side effects and adjust treatment as necessary.

4. Bacterial vs. Viral Infections: Antibiotics are effective against bacterial infections but not viral infections. This distinction is vital because viruses and bacteria are fundamentally different organisms. Bacteria are single-celled organisms that can reproduce independently, while viruses require a host cell to replicate. The reason antibiotics do not work on viruses is that they target specific bacterial processes (like cell wall synthesis or protein synthesis) that viruses do not possess. This is not a matter of strength; rather, it is about the different biological mechanisms of these pathogens.

5. Administration Routes of Antibiotics: Antibiotics can be administered in various forms, including oral (tablets, capsules, liquids) and parenteral (injections). The choice of administration depends on the type of infection, the severity of the condition, and the specific antibiotic. Some antibiotics are available in both oral and injectable forms, but they may be formulated differently. For example, an antibiotic intended for oral use might be in a solid form (tablet or capsule), while the injectable form is typically a liquid. This differentiation allows for tailored treatment based on the patient's needs and the clinical situation.

In conclusion, antibiotics are a powerful tool in treating infections, but their use must be carefully managed to avoid resistance and side effects. Understanding their classification, the rationale behind specialist consultations, their effects on human health, and the differences between bacterial and viral infections is essential for effective treatment. Always consult healthcare professionals for guidance on antibiotic use and to ensure the best outcomes for your health.

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