Liver Health: Long-term Effects of Medication and Monitoring - Gastroenterology and Hepatology

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Could you please provide more details about the liver issues?


1.
Long-term use of Ganciclovir can have side effects.
It may affect other organs, including the kidneys.

2.
Since your liver function has returned to normal but the E antigen has not yet turned negative, it is advisable to have an ultrasound examination every 6 to 12 months.
Thank you for your question.

kevin, 20~29 year old female. Ask Date: 2005/02/16

Dr. Chen Zhiping reply Gastroenterology and Hepatology


Hello, generally speaking, there are no significant side effects from the treatment, and it does not affect other organs.
The e-antigen has not turned negative (treatment should continue), liver function tests are normal, and the treatment goal has not yet been achieved (the e-antigen needs to turn negative to produce e-antibodies).
An abdominal ultrasound is typically recommended every six months, but if necessary, it can be shortened to every three to four months, depending on changes in liver function or the presence of liver nodules or other lesions.
Sincerely, Dr.
Chen Zhiping, Internal Medicine.

Reply Date: 2005/02/16

More Info


When it comes to liver health, understanding the long-term effects of medications and the importance of monitoring is crucial. Let's address your questions regarding the long-term use of medications like Gan An Neng (肝安能) and the necessary follow-up care for liver function.

1. Long-term Use of Gan An Neng: Gan An Neng is a medication often prescribed for patients with chronic hepatitis B and other liver conditions. Generally, the long-term use of this medication is considered safe, and there are no significant reports of severe side effects affecting other organs, such as the kidneys. However, like any medication, it is essential to monitor for potential side effects. Some patients may experience mild gastrointestinal disturbances, but these are typically manageable. Regular blood tests to monitor liver function (including GOT, GPT, and other liver enzymes) are recommended to ensure that the medication is not causing any adverse effects on the liver or other organs over time.

2. Monitoring Liver Function and Ultrasound Frequency: Since your liver function has returned to normal, that is a positive sign. However, the presence of the E antigen indicates that the virus is still active, and it is crucial to continue monitoring your liver health. The frequency of ultrasound examinations can vary based on individual circumstances. For patients with chronic hepatitis B, it is generally recommended to have an ultrasound every 6 to 12 months, especially if there are concerns about liver cirrhosis or the development of liver cancer. Regular monitoring allows for early detection of any changes in liver structure or function, which is vital for timely intervention.

In addition to these points, it is essential to maintain a healthy lifestyle to support liver health. This includes:
- Avoiding Alcohol: Alcohol can significantly impact liver health, especially in individuals with pre-existing liver conditions. Limiting or eliminating alcohol consumption can help prevent further liver damage.

- Healthy Diet: A balanced diet rich in fruits, vegetables, whole grains, and lean proteins can support liver function. Avoiding excessive fats, sugars, and processed foods is also beneficial.

- Regular Exercise: Engaging in regular physical activity can help maintain a healthy weight and reduce the risk of fatty liver disease, which can complicate existing liver conditions.

- Routine Check-ups: Regular visits to your healthcare provider for blood tests and imaging studies are essential. These check-ups can help track the progression of your liver condition and the effectiveness of your treatment.

- Vaccinations: If you have not already done so, consider getting vaccinated against hepatitis A and B, as these viruses can further complicate liver health.

In conclusion, while long-term use of medications like Gan An Neng is generally safe, ongoing monitoring of liver function and regular ultrasound examinations are crucial for managing chronic hepatitis B and ensuring overall liver health. Always consult with your healthcare provider for personalized advice and follow-up care tailored to your specific health needs.

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