Safe Medication Use During Pregnancy: What You Need to Know - Pharmacology

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Medication Use in Pregnant Women


Hello Dr.
Hou: A while ago, I visited a gynecologist due to a urinary tract infection, but it hasn't improved after a long time.
The doctor mentioned that I might have developed antibiotic resistance and prescribed a different medication for me.
I am currently 31 weeks pregnant, but I am still very cautious about taking medication.
I researched the safety of the five medications prescribed by my doctor online, and I found that one of them, "GENURIN," is not recommended for use during pregnancy.
I have also heard that medications should not be taken indiscriminately during the first three months of pregnancy, as it may lead to fetal malformations.
However, since I am now over 30 weeks pregnant and the fetus has already developed, I am concerned about whether it could still cause adverse effects (such as neurological deficits) and this is causing me a lot of distress.
I kindly ask for your guidance, thank you!

chun, 20~29 year old female. Ask Date: 2005/03/07

Dr. Hou Fangmin reply Pharmacology


Hello; every pregnant mother is always particularly concerned about medication issues, and I can relate to that.
The ingredient you mentioned, genurin, contains Flavoxate, which is classified as pregnancy category B.
The pregnancy categories are divided into A, B, C, D, and X.
Generally, category X should never be used, while category B is considered a lower risk.
For pregnant women, it is advisable to avoid it during the early stages of pregnancy, but since you are in the late stages, it is less likely to have an impact.
However, if possible, it is best to avoid taking it altogether.
If you have developed a tolerance, you might consider consulting another hospital, preferably a gynecologist.

Reply Date: 2005/03/07

More Info


When it comes to medication use during pregnancy, safety is a paramount concern for expectant mothers. The potential effects of medications on fetal development can vary significantly depending on the type of drug, the timing of exposure during pregnancy, and the individual health circumstances of the mother.
In your case, you mentioned that you are currently 31 weeks pregnant and have been prescribed a medication called "GENURIN" for a urinary tract infection (UTI). It is understandable to be cautious about any medication during pregnancy, especially considering the potential risks associated with drug use in the first trimester, when the fetus is most vulnerable to teratogenic effects. However, it is also important to recognize that by the third trimester, the fetus has developed significantly, and the risks associated with certain medications may differ.

The classification of medications during pregnancy is typically categorized into five categories (A, B, C, D, and X) based on their potential risks to the fetus. Category A is considered the safest, while Category X indicates that the risks clearly outweigh any potential benefits. GENURIN, which is often used to treat urinary tract infections, may fall into a category that suggests caution. If it is classified as Category D or X, it is generally advised against during pregnancy due to known risks.

It is crucial to have an open dialogue with your healthcare provider about the medications you are taking. If GENURIN is not recommended for use during pregnancy, your doctor should be able to provide alternative treatments that are safer for both you and your baby. Additionally, if you have concerns about the potential long-term effects of any medication taken during pregnancy, including risks of neurological deficits or other developmental issues, it is essential to discuss these with your healthcare provider. They can provide reassurance based on the latest research and guidelines.

Moreover, while the first trimester is indeed a critical period for fetal development, it is also important to note that the third trimester is not without its own risks. Certain medications can still affect the fetus's development or lead to complications during labor and delivery. Therefore, it is advisable to avoid any unnecessary medications and to use the lowest effective dose if medication is required.

In summary, while you are now in the later stages of pregnancy, it is still essential to be cautious about medication use. Always consult with your healthcare provider regarding the safety of any prescribed medications, especially if you have concerns about their potential effects on your baby. They can help you weigh the risks and benefits and ensure that you receive the safest and most effective treatment for your condition. Your health and the health of your baby are of utmost importance, and your healthcare provider is your best resource for navigating these concerns.

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