Tragic Chemotherapy Experience: A Family's Heartbreaking Journey - Oncology

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About cancer chemotherapy?


On November 2, 2005, my wife was admitted to the Hematology and Oncology Department of Kaohsiung Chang Gung Memorial Hospital for chemotherapy due to cancer.
The attending physician was Dr.
Tang Yeh.
My wife passed away on November 21, 2005.
During the chemotherapy process, the absurd medical practices of Dr.
Tang Yeh caused immense pain for our family! It is shocking that a so-called top-tier hospital like Chang Gung has such incompetent attending physicians.
I cannot help but ask: Does Chang Gung Hospital require its physicians to continuously update their knowledge and not rely on medical techniques from ten or twenty years ago to treat cancer patients who are fighting for their lives? I am just an ordinary citizen, without power or influence; Kaohsiung Chang Gung Hospital will not heed my protests or claims for compensation.
I can only state the facts, hoping that this incompetent doctor will not harm anyone else! (I firmly believe that there must have been other patients who died under unclear circumstances before my wife; they just did not voice their experiences!) Below is a detailed account of my wife's medical treatment, and I am sure you will be astonished after reading it!
Dr.
Tang Yeh's absurd medical record: On November 2, my wife was admitted to the trauma ward on the 6th floor of the medical building at Kaohsiung Chang Gung Hospital (as there were no available beds in the Hematology and Oncology Department on the 13th floor) and underwent X-ray and blood tests.
On November 3, she was supposed to receive chemotherapy in the afternoon, but Dr.
Tang did not show up and only informed the nursing station by phone that a trauma physician should administer the chemotherapy.
However, the trauma physician was hesitant to do so, so Dr.
Tang instructed the nursing staff to store the chemotherapy drugs in the refrigerator until he could administer them the next day.

On November 4, Dr.
Tang finally appeared and began administering the chemotherapy drugs around 9 AM.
The chemotherapy medications included 5-FU (3600 mg), Mitomycin (8 mg), and Cisplatin (70 mg).
The infusion of 5-FU consisted of three bags, which would take at least three days (72 hours) to complete.
I noticed that the 5-FU infusion bag was labeled "limited to water," but I did not understand what that meant.

On November 5, the second day of chemotherapy, my wife developed diarrhea and began experiencing incontinence.
In the afternoon, she complained of abdominal pain, so I contacted Dr.
Tang to return to the hospital (it was Saturday, and Dr.
Tang was on leave).
When he arrived, he drained about 600 cc of abdominal fluid from my wife.
After returning to the nursing station, Dr.
Tang shockingly said to the nursing staff, "Damn it! We didn't drain much fluid, and it was such a hassle!" (Dr.
Tang was unaware that someone was standing behind him.) What surprised me the most was that Dr.
Tang drained the fluid by directly inserting a needle into my wife's abdomen without using ultrasound to locate the fluid first, which is the standard procedure.
On November 6, I initially thought the chemotherapy would be completed today, but due to interruptions in the infusion, it continued.
On November 7, around 8:30 PM, we finally finished administering the three bags of 5-FU.
My wife appeared very weak, and I felt heartbroken!
On November 8, after Dr.
Tang's rounds, he prescribed discharge medications for my wife, stating that she could go home to recuperate but needed to return for outpatient follow-up and a second round of chemotherapy on December 1.
Around 1 PM that afternoon, my wife began exhibiting signs of mental disturbance, appearing very dazed and behaving like a little girl.
I quickly notified the nursing station and contacted Dr.
Tang.
When he arrived, he seemed at a loss and merely said my wife was "possessed!" before turning and leaving the room.
I was shocked and helpless! Is this what a so-called top-tier physician at Kaohsiung Chang Gung Hospital is like?!
On November 9, my wife's memory seemed to have vanished; she did not recognize family members and showed no response when spoken to.
My family and I were extremely anxious, as other chemotherapy patients did not exhibit such symptoms.
Dr.
Tang did not take any action, and my wife could only lie in bed while the disease ravaged her.
(According to standard procedures, after chemotherapy, normal saline should be administered to help metabolize the chemotherapy drugs, but Dr.
Tang did not do this!) My family began searching for information on related symptoms to help alleviate my wife's suffering.
Eventually, in the evening, my brother-in-law found information about similar cases and related treatments through a friend at Kaohsiung Veterans General Hospital.
The relevant medical journals included: 1.
El Amrani et al, 1998; 2.
Yeo et al, 1999; 3.
Luppi et al, 1996; 4.
Bixenman et al, 1997; 5.
Nichols et al, 1976; 6.
Bergevin et al, 1975; 7.
Boileau et al, 1971; 8.
Gottlieb & Luce, 1971; 9.
Risso et al, 1997; 10.
Pirzada et al, 2000; 11.
Walker et al, 1998; 12.
Hitchins & Thomson, 1988; 13.
Verschraegen et al, 1995; 14.
Mollman, 1990; 15.
Narin & Rierson, 1979; 16.
Mollman et al, 1988; 17.
Walther et al, 1987; 18.
Pace et al, 2003; 19.
Van der Hoop et al, 1990; 20.
Bellin & Selin, 1988; 21.
Ritch, 1988; 22.
Mead et al, 1982.
On November 10, I presented the relevant information to Dr.
Tang.
It was evident that he was completely unaware that a small number of patients could experience such side effects after receiving that type of chemotherapy! In the afternoon, the nursing staff finally came to administer IV fluids, hoping to dilute and metabolize the residual chemotherapy drugs in my wife's body.
My wife had not eaten for several days, but the diarrhea persisted, and she was still experiencing incontinence.

On November 11, the IV fluids continued, but my wife was vomiting, had diarrhea, and was still incontinent.
She could not speak, and her limbs could not move normally or support her weight, and her gaze remained vacant.
On November 12, the IV fluids continued, and she still had diarrhea and incontinence.
She could move slightly but very slowly, could hear but still could not speak.
Today, she was able to consume some liquid food.

On November 13, the IV fluids continued, but my wife's condition was worse than the previous day, and she appeared very confused.
On November 14, the IV fluids continued, and the diarrhea and incontinence worsened (at least four times an hour).
Her hands trembled and curled.
I informed Dr.
Tang of this condition, and he said, "The intestines are like a stinky sewer; let them expel the dirty stuff!" Dr.
Tang did not take any measures to stop the diarrhea.

On November 15, the IV fluids continued, and my wife still had diarrhea and incontinence.
Around 2 PM, she experienced muscle spasms.
A physician from the nursing station administered an anti-spasm injection, and my wife's consciousness slightly returned, but her body remained weak.
On November 16, the IV fluids continued, and she still had diarrhea and incontinence.
Her limbs could not move freely or support her weight.
Concerned about my wife's nutritional status, we began adding nutritional IV fluids.

On November 17, the IV fluids continued, and her consciousness slightly improved.
The diarrhea and incontinence were still severe (more than ten times an hour).
At this point, Dr.
Tang still did not take any measures to stop the diarrhea.
On November 18, the IV fluids continued, and she still had diarrhea and incontinence, and her limbs could not exert force, and her mental state remained confused.
Dr.
Tang informed me that my wife was experiencing an electrolyte imbalance due to diarrhea, and the potassium ion concentration in her blood was too low, causing her muscles to be unable to function.
He stated that they would start adding 15% potassium ions to the IV fluids to improve her condition.

On November 19, the IV fluids continued, and she still had diarrhea and incontinence, and her limbs could not exert force.
That evening, my wife's emotions became very agitated, so to avoid disturbing the neighboring patient, she was moved to a private treatment room.
On November 20, the IV fluids continued, and she still had diarrhea and incontinence, and her limbs could not exert force or move freely.
In the morning, when Dr.
Tang came for rounds, I asked him, "After chemotherapy, what is my wife's tumor marker (CEA) level now?" Dr.
Tang and I checked the medical records on the computer, and my wife's tumor marker level had dropped from over 700 to 2.4 (the standard value is 4.0).
I was so happy! The treatment was very effective, and I shared the news with my wife.
After hearing it, she fell asleep deeply, something she hadn't done in a long time.
When my wife woke up that evening, she was fully alert, but the diarrhea, incontinence, and inability to move her limbs persisted.
That night, we returned to her original ward.

On November 21, my wife's condition appeared quite good, although she was still weak.
She was mentally clear and could tell me she needed to use the restroom, which made me very happy! When Dr.
Tang came for rounds, he informed me that once the electrolyte levels in her blood stabilized, she could be discharged to recuperate.
Suddenly, Dr.
Tang noticed that the potassium ion concentration in the IV fluids was only 5%, which explained why my wife's potassium levels had been imbalanced! This IV fluid had been administered for two days (48 hours)!! Although the nurse immediately changed it, everything was too slow.
At around 12:15 PM, my wife suddenly lost consciousness and could not breathe.
Dr.
Tang and the nurses began the first round of emergency resuscitation.
My wife was intubated, and her condition seemed dire! Dr.
Tang suspiciously asked me, "Strange, why is there so much water in your wife's lungs?" I was stunned! Is this guy really an attending physician?! How could he not notice the fluid accumulation in her lungs after daily chest X-rays? Was he negligent or just making up a serious situation to placate the family?! Due to the low potassium levels in my wife's blood, all her muscles could not function normally, and her albumin levels were too low, making her blood pressure nearly undetectable!
At around 3:15 PM, my wife's heart rate stopped again, prompting the second round of emergency resuscitation.
At this point, Dr.
Tang was nowhere to be found, and another physician was called to assist.
After several minutes, the physician's resuscitation efforts were unsuccessful, and my wife passed away...
She was only 38 years old!!!
On November 22, I went to the Hematology and Oncology Department of Kaohsiung Chang Gung Hospital to request a death certificate from Dr.
Tang, but he was on leave that day! Was it a coincidence or a sign of guilt?? The death certificate was issued by another physician.........

PS: I truly cannot agree with the professional competence of Dr.
Tang Yeh from Kaohsiung Chang Gung Hospital!! He does not engage in self-improvement and still dares to treat patients!!! His medical knowledge is lacking, and only after the family sought related symptom information did he know how to proceed with treatment.
This is truly absurd! The nursing staff's professional ethics are non-existent; they even got the IV fluid concentration wrong and were unaware! It is shameful, truly shameful!!

Laoshi, 40~49 year old female. Ask Date: 2006/01/27

Dr. Fan Sheng reply Oncology


Teacher: Due to the unique constitution of certain patients, high-dose continuous infusion of 5-FU chemotherapy can interfere with liver detoxification functions, leading to hepatic encephalopathy that affects central nervous system function.
The treatment indeed involves the use of medications that induce diarrhea to expel toxins from the body through the intestines and reduce toxin absorption.
Under this treatment, most patients are able to regain consciousness, similar to Mrs.
Ling.
As for the subsequent sudden changes in vital signs, it is difficult to determine the cause based on the content of the letter; we appreciate your understanding.

Reply Date: 2006/01/27

More Info


The tragic experience you shared regarding your wife's chemotherapy journey is both heartbreaking and alarming. It highlights several critical issues surrounding cancer treatment, patient care, and the responsibilities of healthcare professionals.
Firstly, it is essential to acknowledge that chemotherapy, while a common and often necessary treatment for cancer, can have severe side effects. These can include nausea, vomiting, diarrhea, and even neurological symptoms, as you described. The medications used in chemotherapy, such as 5-FU, Mitomycin, and Cisplatin, are potent and can significantly impact a patient's overall health. The management of these side effects is crucial and should be handled with care and expertise by the treating physician.

In your account, it appears that there were several lapses in the standard of care provided by the attending physician, Dr. Tang. For instance, the decision to have another department administer chemotherapy without proper oversight raises concerns about the coordination of care. Additionally, the lack of timely intervention for your wife's severe side effects, such as diarrhea and abdominal pain, suggests a failure to monitor and respond to her condition adequately. Chemotherapy protocols typically include measures to manage side effects proactively, including hydration and electrolyte management, which seem to have been neglected in your wife's case.

The emotional and psychological toll on both the patient and the family during such a challenging time cannot be overstated. The fear and anxiety associated with cancer treatment can be overwhelming, and it is the responsibility of healthcare providers to offer not only medical support but also emotional reassurance. The apparent lack of communication and empathy from Dr. Tang, as you described, exacerbates the distress experienced by patients and their families.

Moreover, the importance of continuous education and training for healthcare professionals cannot be overlooked. Medicine is an ever-evolving field, and it is vital for practitioners to stay updated on the latest treatment protocols and patient care strategies. The concerns you raised about Dr. Tang's knowledge and approach to treatment are valid and highlight a systemic issue that needs addressing within healthcare institutions.

In terms of seeking recourse, it is crucial for patients and their families to voice their concerns and experiences. Hospitals typically have patient advocacy services or ombudsmen who can assist in addressing grievances. While it may feel daunting, sharing your experience can lead to improvements in patient care and prevent similar tragedies from occurring in the future.

Lastly, it is essential for families to seek second opinions and to be proactive in their loved ones' healthcare. Engaging with multiple healthcare providers can provide a broader perspective on treatment options and potential side effects. Support groups and counseling services can also be beneficial for families navigating the complexities of cancer treatment.

In conclusion, your wife's experience underscores the need for compassionate, coordinated, and knowledgeable care in oncology. It is a reminder of the vulnerabilities faced by patients and their families during such a challenging time and the critical role that healthcare providers play in ensuring a supportive and effective treatment journey.

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